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5th International AIDS ConferenceMontreal, Quebec, Canada — Jun 4-9, 1989 |
Int Conf AIDS 1989 Jun 4-9; 5:164 (abstract no. A.522)
Blythe S, Castillo-Chavez C; Strathclyde University, Glasgow, Scotland
OBJECTIVE: To develop an alternative to proportionate mixing in sexually transmitted disease models.
METHODS: Starting from the three fundamental constraints on a mixing function (it must be positive, normalized, and conserve the number of partnerships), a new mixing model can be constructed by finding an appropriate transformation of a suitable function (describing mixing between individuals of similar activity).
RESULTS: A new mixing model is derived, based on a transformation of a local mixing function ("like-with-like") which has the property f(x-y) = f(y-x). Different choices of f provide different degrees of localized mixing in the population, and affect the dynamics of an STD epidemic. We look at three alternatives: Gaussian, rectangular, and "sharp" f superimposed on the general mixing.
CONCLUSION: Predictions of epidemics of STDs are very sensitive to the extent of like-with-like mixing in the population.
890604
A522
Copyright © 1989 - International AIDS Society (IAS). Reproduction of this abstract (other than one copy for personal reference) must be cleared through the IAS.