5th International AIDS Conference


Montreal, Quebec, Canada — Jun 4-9, 1989

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Prevalence of different retrovirus in Spanish intravenous drug users during 1.987-1.988. Clinical findings of seropositives.

Int Conf AIDS 1989 Jun 4-9; 5:173 (abstract no. A.576)
Contreras G, Garcia Saiz A, Vallhonrat E, Varela JM, Peres Alvarez L, Najera R; Instituto de Salud Carlos III, Madrid, Spain

OBJECTIVE: - To analyze the seroprevalence of HIV-2 and HTLV-I in Spanish intravenous drug users (IVDA) and the clinical findings of seropositives to HIV-1 in relationships to the antigenemia status. We determine as well -- the incidence of coinfection with other infectious agents.

METHODS: - Sera collected from 4.269 IVDAs were tested (1,888 in 1.987 and 2.381 in 1.988). The presence of anti-HIV-1, -HIV-2, -HTLV-I antibodies was revealed by ELISA. IFA and WB was used as a confirmatory test. -- Antigen ELISA test was used for HIV p24 antigen detection.

RESULTS: - The prevalence of HIV-1 was 64,7% in 1.987 and 61,9% in 1.988. Data collection are ongoing and analysis suggests up to date that a 70% of seropositives still asymptomatic and a 30% shows some pathology related with HIV infection. We are currently performing the seroprevalence of anti-HIV-2 and HTLV-I in a group of IVDAs with statistic significance. A 8% shows HBsAg and a 2,5% active syphilis.

CONCLUSION: - The prevalence rate, about 60% during 1.987 and 1.988 and similar to previous years, is high enough to indicate a serious problem of HIV infection among the Spanish drug users. Very preliminary results indicate no incidence of HIV-2 and HTLV-I in this IVDA population.

Keywords: AEGIS, Substance Abuse, Intravenous, Prevalence, HIV-2, HTLV-I Antibodies, HIV-1, HIV Infections, Hispanic Americans, Human T-lymphotropic virus 1, Seroepidemiologic Studies, Incidence, epidemiology, ICA5KWDaegis,substanceabuse,intravenous,prevalence,hiv-2,htlv-iantibodies,hiv-1,hivinfections,hispanicamericans,humant-lymphotropicvirus1,seroepidemiologicstudies,incidence,epidemiology,ica5

890604
A576

Copyright © 1989 - International AIDS Society (IAS). Reproduction of this abstract (other than one copy for personal reference) must be cleared through the IAS.