AEGiS-08IAC: A comparative study of the efficacy of ciprofloxacin and erythromycin in chancroid.

8th International AIDS Conference


Amsterdam, Netherlands — July 19-24, 1992

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A comparative study of the efficacy of ciprofloxacin and erythromycin in chancroid.

Int Conf AIDS 1992 Jul 19-24; 8:We54 (abstract no. WeB 1050)
Solorzano R; STD clinic, Clinica Municipal No. 3, Guatemala, City.

OBJECTIVE: To determine the efficacy and safety of ciprofloxacin and Erythromycin in the treatment of Chancroid Ulcers.

METHODS: 240 patients with clinical diagnosis of chancroid were included. Two groups of 120 patients each were studied. One group was treated with Ciprofloxacin 1 gr. PO as a single dose and the second group was treated with standard a dose of Erythromycin for ten days.

RESULTS: No differences were noted between the two groups regarding demographic characteristics, sexual behaviour, or clinical appearance of the ulcers. A good clinical response with Ciprofloxacin and Erythromycin was observed 98% and 95% respectively. More gastrointestinal adverse effects, were observed in the group treated with Erythromycin.

CONCLUSION: Ciprofloxacin 1 gr. PO as single dose, is an effective treatment for clinical proven Chancroid, but Erythromycin is also effective. The two drugs can be recommended as first line therapy of Chancroid.

Keywords: AEGIS, Chancroid, Ciprofloxacin, Erythromycin, Anti-Infective Agents, Fluoroquinolone, Antibiotics, Macrolide, Corneal Ulcer, Ulcer, Human, ICA8KWDaegis,chancroid,ciprofloxacin,erythromycin,anti-infectiveagents,fluoroquinolone,antibiotics,macrolide,cornealulcer,ulcer,human,ica8
920719
WeB1050

Copyright © 1992 - International AIDS Society (IAS). Reproduction of this abstract (other than one copy for personal reference) must be cleared through the IAS.