AEGiS-08IAC: HIV seroconversion related to heterosexual activity in discordant Haitian couples.

8th International AIDS Conference


Amsterdam, Netherlands — July 19-24, 1992

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HIV seroconversion related to heterosexual activity in discordant Haitian couples.

Int Conf AIDS 1992 Jul 19-24; 8:We61 (abstract no. WeC 1087)
Deschamps MM, Pape JW, Beaulieu ME, Thermil K, Johnson WD Jr; GHESKIO, Port-au-Prince, Haiti.

OBJECTIVES: To determine the incidence of HIV seroconversion and the associated co-factors in sexually active (SA) discordant (D) couples.

METHODS: From 10/85 to 10/91, despite counseling 158 of the 380 (D) couples enrolled in our clinic remained (SA): 125 females (F) (HIV-) spouses and 33 males (M) (HIV-) spouses of HIV+ index cases of the opposite sex. Couples were evaluated clinically at q. 3 months with a standardized questionnaire, and repeat HIV test by (EIA) for the (HIV-) spouses. Criteria for seroconversion included EIA- sera with -Western Blot (WB), which turned + by EIA with WB confirmation (CDC criteria).

RESULTS: During a mean follow-up period of 27.5 mo (3-87 mo), of the (SA) (D) couples a seroconversion rate of 11% (17/158) was observed. Regular condom use was protective, since none of those who always used condom (n = 39) seroconverted (p = .005). 14% (17/119) of (D) couples who did not use condom seroconverted during a mean period of (SA) of 17 mo (3-70). The incidence of seroconversion in this group was 10.27% or 17 cases/166 person years of observations, comparable for (F) and (M). Factors significantly associated with HIV(S) (univariate analysis): TABULAR DATA, SEE ABSTRACT VOLUME.

CONCLUSION: 1. Regular condom use is protective in (SA) (D) couples. 2. Incidence of seroconversion in (SA) (D) non condom users was 10.27% and is associated with predisposing factors. This high risk population could be ideal for vaccine intervention.

Keywords: AEGIS, Heterosexuality, HIV Seropositivity, Condoms, HIV Seronegativity, HIV, HIV Infections, Incidence, Counseling, HIV Antibodies, Coitus, Blotting, Western, Haiti, Human, Female, Male, immunology, ICA8KWDaegis,heterosexuality,hivseropositivity,condoms,hivseronegativity,hiv,hivinfections,incidence,counseling,hivantibodies,coitus,blotting,western,haiti,human,female,male,immunology,ica8
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WeC1087

Copyright © 1992 - International AIDS Society (IAS). Reproduction of this abstract (other than one copy for personal reference) must be cleared through the IAS.