AEGiS-11IAC: Kaposi's sarcoma and AIDS. A hundred autopsies study in Brazil.

11th International AIDS Conference


Vancouver, British Columbia — July 7-12, 1996

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Kaposi's sarcoma and AIDS. A hundred autopsies study in Brazil.

Int Conf AIDS 1996 Jul 7-12; 11:448 (abstract no. Pub.B.1061)
Correa PA, Basilio CA, Valle HA, Moraes AL, Monteiro GB, Hirt RT, Coelho-de-Sa EC; Gaffree e Guinle University Hospital, University of Rio de Janeiro, Rio de Janeiro, Brazil. Fax: +55-21-2647175.

OBJECTIVE: To evaluate the incidence, topographical distribution and mortality related to Kaposi's Sarcoma (KS) in patients with AIDS.

METHODS: A descriptive study of 100 AIDS patients autopsies, performed from 1984 to 1994, was made by sistematic histopathological examination and imunohistochemical methods.

RESULTS: The patient's profile was: males (82%), whites (72%) and an average age of 35 years (range 15 - 62). The risk factors for AIDS were: homosexuality (55%), injecting drug-use (19%), bisexuality (15%), blood transfusions (10%), male-to-female transmission (3%). Nineteen KS cases were found. Multiple organs were involved in 11 cases and single organs in 8 cases. Other tumors had a lower incidence. The most affected organs were: skin (73.6%), lung (42.1%), small-intestine (31.5%), stomach (21%) and lymph nodes (21%). The most common opportunistic infections seen in patients with KS were: pyogenic bacteria (68.4%), Candida albicans (68.4%), Cytomegalovirus (42.1%) and Herpes simplex viruses (15.7%). KS was the cause of 4% of the overall mortality.

CONCLUSIONS: KS is the most common neoplasm associated with AIDS. Important cutaneous, digestive and pulmonary involvement were found. Pulmonary KS plays a relevant role as a mortality factor.

Keywords: AEGIS, Sarcoma, Kaposi, Acquired Immunodeficiency Syndrome, Autopsy, Skin Neoplasms, Homosexuality, Risk Factors, Bisexuality, Incidence, Neoplasms, Cytomegalovirus, Cytomegalovirus Infections, Sezary Syndrome, Brazil, Human, Male, Female, ICA11KWDaegis,sarcoma,kaposi,acquiredimmunodeficiencysyndrome,autopsy,skinneoplasms,homosexuality,riskfactors,bisexuality,incidence,neoplasms,cytomegalovirus,cytomegalovirusinfections,sezarysyndrome,brazil,human,male,female,ica11

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PubB1061

Copyright © 1996 - International AIDS Society (IAS). Reproduction of this abstract (other than one copy for personal reference) must be cleared through the IAS.