AEGiS-11IAC: Clinico-epidemiologic profile of HIV infection at a tertiary care center in North India.

11th International AIDS Conference


Vancouver, British Columbia — July 7-12, 1996

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Clinico-epidemiologic profile of HIV infection at a tertiary care center in North India.

Int Conf AIDS 1996 Jul 7-12; 11:455 (abstract no. Pub.C.1109)
Wali JP, Wig N, AggarwalL P, Handa R; All India Institute of Medical Sciences, New Delhi, India. Fax: 91-11-6862663. E-mail: jpwali@Medinst.ernet.in.

ISSUE:India being a vast country, regional differences in the spectrum of HIV infection exist. However, the presently available data is scant.

OBJECTIVE: To study the clinico-epidemiologic profile of HIV-positive cases seen at a large teaching hospital in North India. Methods and

RESULTS: Retrospective analysis of 164 HIV-positive cases(137 male and 27 female)seen over a period of 9 years(1986-94)was carried out. Of the 136 adults, 117 were in the sexually active age group(20-40 years). Majority of the patients(80%) hailed from urban areas, notwithstanding the fact that 65-70% of the Indian population is rural. The modes of transmission included heterosexual contact(60%), blood transfusions (38.4%) and intravenous drug use(1.2%). Of the 50 symptomatic patients, 12 had PGL(CDC group III) and 38 were CDC Group IV. Opportunistic infections encountered were oral thrush(30), systemic candidiasis(4), tuberculosis(20), PCP(6), cryptococcois(4), cryptosporidiosis(2), and multidermatomal herpes zoster(2). No case of Kaposi's sarcoma or lymphoma was seen.

CONCLUSION: The commonest mode of transmission was heterosexual contact in sharp contrast to north eastern states of India where IVDU is the major route of transmission. Candidiasis and tuberculosis constituted the majority of opportunistic infections seen. Wider availability of diagnostic facilities, greater epidemiologic inputs and creation of a regional data base are urgently needed to tackle this scourge.

Keywords: AEGIS, HIV Infections, Tuberculosis, Candidiasis, Oral, HIV Seropositivity, Opportunistic Infections, Centers for Disease Control and Prevention (U.S.), Referral and Consultation, Blood Transfusion, Retrospective Studies, India, United States, Adult, Animal, Female, Male, Human, epidemiology, ICA11KWDaegis,hivinfections,tuberculosis,candidiasis,oral,hivseropositivity,opportunisticinfections,centersfordiseasecontrolandprevention(uKWDsKWD),referralandconsultation,bloodtransfusion,retrospectivestudies,india,unitedstates,adult,animal,female,male,human,epidemiology,ica11

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PubC1109

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