AEGiS-12IAC: No differences in Mexico between HIV-1 subtype B, sexual preferences and routes of transmission.

12th International AIDS Conference


Geneva, Switzerland - June 28-July 3, 1998

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No differences in Mexico between HIV-1 subtype B, sexual preferences and routes of transmission.

Int Conf AIDS 1998 Jun 28-Jul 3; 12:18 (abstract no. 11180)

Vasquez-Valls E, De Quevedo JJ, Lopez-Marquez FC, Escoto-Delgadillo M, Campos-Lopez PI
Instituto Mexican Del Seguro Social, Guadalajara, Mexico.

OBJECTIVE: To identify the association between the HIV-1 subtype B, sexual preferences and routes of transmission.

METHODS: Clinical histories and blood samples were obtained from 308 HIV seropositives, 194 men and 114 women, they were classified in order to their sexual preference and route of HIV transmission. The sera were tested by enzyme -linked immunosorbent assay (ELISA) with synthetic peptides 10 aminoacides long, from the C2V3 region of the HIV-1 subtypes A, B, C, D and E. Nested polymerase chain reaction (PCR) amplification was made as a comparative test.

RESULTS: Of all participants, 155 (50.32%) refered to have a homosexual preference; 115 (37.33%) were heterosexual and 38 (12.33%) were bisexual. Out of which 274 (88.96%) were positive to subtype B, and 34 (11.03%) to another no B subtype. Among B positives, 174 (63.50%) acquired the HIV by sexual contact; 57 (20.80%) by blood transfussion and 43 (15.69%) by perinatal route. Of the no B cases, 24 (70.58%) acquired the HIV-1 by sexual route; 9 (26.47%) by blood transfussion and one (2.94%) trough vertical transmission (p = NS). V3 serology and nested PCR amplification correlation was 90.1% for subtype B.

CONCLUSION: In this sample, we do not find any association between the B sutype and the sexual preference or route of transmission between the seropositives in the west of Mexico.

Keywords: AEGIS, HIV-1, Sex Behavior, HIV Infections, Disease Transmission, Vertical, Heterosexuality, Homosexuality, Polymerase Chain Reaction, HIV Seropositivity, Enzyme-Linked Immunosorbent Assay, Mexico, Human, Female, Male, transmission, ICA12KWDaegis,hiv-1,sexbehavior,hivinfections,diseasetransmission,vertical,heterosexuality,homosexuality,polymerasechainreaction,hivseropositivity,enzyme-linkedimmunosorbentassay,mexico,human,female,male,transmission,ica12
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Copyright © 1998 - International AIDS Society (IAS). Reproduction of this abstract (other than one copy for personal reference) must be cleared through the IAS.