AEGiS-13IAC: HIV-1 sero-prevalence in patients with cervical cancer in Mulago Hospital in Uganda.

13th International AIDS Conference

Durban, South Africa - July 9-July 14, 2000

HIV-1 sero-prevalence in patients with cervical cancer in Mulago Hospital in Uganda.

Int Conf AIDS 2000 Jul 9-14; 13:42 (abstract no.. LbPeB7041)

Sekitime Kigongo W, Lule JC, Mmiiro FA, Wabwire FM, Biryabwaho, Downing, Bagenda D
Uganda WHO Country Office, Kampala. Fax: +256 41 344 059.

OBJECTIVES: To assess the sero-prevalence of HIV- 1 infection in patients with cervical cancer. Whether HIV-1 infection has a relationship with the histological appearance of the tumour. Whether HIV- 1 infection could be a risk factor in patients aged less than 30 years.

METHODOLOGY: 117 Patients in Mulago Hospital with histologically proven cervical cancer had their blood taken off for HIV ELISA test. Data on their socio-demographic characteristics, sexual behaviour, risk factors for cervical cancer and HIV infection as well as signs of the two diseases were collected. For each patient enrolled in the study, a control for age and parity was matched from patients attending the medical outpatients for other ailments.

RESULTS: 18 (15.48) patients with cervical cancer and 15 (12.9%) of the controls were HIV seropositive which wasn't statistically significant (P=0.59 chi = 0.29) Alcoholism was of borderline significance (38, 32.5%) compared to 19 (16.2%) among controls (P=0.0.38, chi=8.4) There was no significant relationship in those patients less than 30 years with the tumor nor differentiation/HIV serostatus.

CONCLUSION: These preliminary findings suggest that HIV-1 infection is not a risk factor for cervical cancer.

Keywords: AEGIS, HIV-1, Prevalence, HIV Infections, HIV Seropositivity, Risk Factors, Cervix Neoplasms, Hospitals, Case-Control Studies, Uganda, Female, Human, epidemiology, AIDS
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