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13th International AIDS ConferenceDurban, South Africa - July 9-July 14, 2000 |
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. MoOrB236)
Ebrahim SH, Selik R, McKenna MT, Hamers F, Seeff L
S.H. Ebrahim, C.D.C, Mailstop K-55, 4770 Buford Hway NE, Atlanta, GA 30341, United States, Tel.: +1 770 488 42 27, Fax: +1 770 488 46 39, E-mail: sbe2@cdc.gov
OBJECTIVE: To assess the trends in invasive cervical cancer (CCA) as an AIDS-defining condition.
METHODS: We analyzed the AIDS surveillance data from Europe (reported by 15 countries of the WHO-European region) and the USA (excludes cases diagnosed based solely on immunologic criteria), among women aged 15 years or older, 1994 through 1998.
RESULTS: During 1994-1998, CCA was the most common malignancy among women with AIDS in both Europe (2.7%, 393/14,348) and the USA (2.1%, 580/28,024). In Europe and the USA,, CCA was the only AIDS-defining condition for 90% of women with CCA and AIDS. Over the period 1994 to 1998, the percentage of women who had CCA as the AIDS-defining condition remained stable in Europe whereas it declined in the USA from 2.7% to 1.7% (p = >0.001). Overall, the percentage with CCA was significantly higher among women who acquired HIV through intravenous drug use (Europe 3.5%, USA 2.3%) or heterosexual contact (Europe 2.1%, USA 2.1%) than the remainder of the women (Europe 0.7%, USA 1.6%). In Europe, CCA peaked among women aged 31 to 35 years (3.5%), whereas in the USA, CCA declined (p > 0.001) with increasing age, from 2.7% (15-20 years) to 1.2% (51 years old or older).
CONCLUSIONS: Women with HIV/AIDS had a substantial high risk of invasive cervical cancer in both Europe and the USA. Women of all ages who are at risk of HIV should be targets for cervical screening.
Copyright © 2000 - International AIDS Society (IAS). Reproduction of this abstract (other than one copy for personal reference) must be cleared through the IAS.
