Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA282)
Kuhn L, Coutsoudis A, Meddows-Taylor S, Mngqundaniso N, Trabattoni D, Clerici M, Shearer G, Tiemessen C, Gray G; L. Kuhn, Columbia University, Sergievsky Center, 630 W 168th Street, New York, United States, Tel.: +1 212 305 2398, Fax: +1 212 305 2426, E-mail: lk24@columbia.edu
Background: Acquired HIV-specific cell-mediated immune responses are observed in some HIV-exposed but uninfected individuals, and it has been inferred, but not demonstrated, that these responses constitute a part of natural protective immunity to HIV. The context of maternal-infant transmission in breast-feeding popula
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA283)
Teixeira L, Valdez H, Patki A, Gross B, Koup R, McCune J, Hellerstein M, Badley A, Lederman M; L. Teixeira, Case Western Reserve University, 2061 Crnell Rm 301B, Cleveland, OH 44106, United States, Tel.: +1 216 844 2057, Fax: +1 216 844 5523, E-mail: valdez.hernan@clevelandactu.org
Introduction: We performed a cross-sectional analysis to compare patients with sustained virologic responses and large CD4+ cell responses (CD4+ cell rise of at least 200 cells/uL, responders) and patients with poor CD4+ cell responses (CD4+ cell rise less than 100 cells/uL; poor-responders) after HAART. Methods: Perip
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA284)
Malhotra U, Dutta S, Holte S, Berrey MM, Corey L, McElrath MJ; U. Malhotra, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave. N., D3-100, Seattle, WA 98109, United States, Tel.: +1 206 667 6738, Fax: +1 206 667 4411, E-mail: uma@u.washington.edu
Background: Most patients receiving combination therapy early in infection respond favorably, but not all maintain viral suppression. To address this, we prospectively evaluated 21 patients with early HIV-1 infection to assess potential genetic inheritance patterns that may be associated with virologic and immunologic
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA285)
Sinet M, Deschemin JC, Dupuis M, Dalod M, Chotard E, Meyer L, Deveau C, Delfraissy JF, Venet A; M. Sinet, Laboratoire Vni Faculte De Medicine, 63 Rue Gabriel Peri, Le Kremlin Bicetre 94276, France, Tel.: +33 1 49 596 719, Fax: +33 1 49 596 753, E-mail: martin.sinet@rb.u_psud.pg
Background: To characterize the specific immune CD4+ and CD8+ T cell responses during primary HIV infection and to explore changes after treatment and their relationship to virological responses. Methods: T cell responses were evaluated in 24 subjects with primary HIV infection included in the French PRIMO cohort. Afte
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA286)
Mallal S, Moore C, John M, James I, Nolan D, Sayer D, Witt C;;; S. Mallal, Royal Perth Hospital, Department of Clinical Immunology, Wellington Street, Perth 6000, Australia, Tel.: +61 8 922 428 99, Fax: +61 8 922 429 20, E-mail: mallal@prodigal.murdoch.edu.au
Background: Nonsynonymous (NS) mutations in HIV reverse transcriptase(RT) sequence encoding HLA class I restricted CTL epitopes that lead to viral escape from host CTL responses have been described within individuals.The frequency and importance of CTL escape mutation has not been defined at a population level. Methods
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA287)
Smith K, Steffens C, Truckenbrod A, Landay A, Russert M, Al-Harthi L; K. Smith, Rush Presbyterian St. Luke's Medical Center, 600 S. Paulina Suite 143, Chicago, IL, 60612, United States, Tel.: +1 312 942 20 51, Fax: +1 312-942-82-00, E-mail: ksmith2@rush.edu
Objective: To examine the impact of PI Vs non-PI regimens on immune reconstitution, we examined T-lymphocyte subsets, activation markers, thymic size and output in HIV+ pts with VL>50. We also compared thymic output between HIV+ pts and HIV- age-matched controls. Methods. T lymphocyte subsets and activation status were
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA288)
Pomerantz R, Foley H, Schnell M, Siler C, Dietzschold B, McGettigan J; R. Pomerantz, Thomas Jefferson University, 1020 Locust St., Suite 329 JAH, Philadelphia, PA 19107, United States, Tel.: +1 215 503 85 75, Fax: +1 215 923 19 56, E-mail: roger.j.pomerantz@mail.tju.edu
To develop a live-virus strategy in the development of HIV-1 vacccines, recombinant replication-competent rabies virus (RV) vaccine strain-based vectors expressing HIV-1 envelope protein (gp160) were constructed from both a laboratory-adapted (CXCR-4-tropic) and a primary (dual-tropic) HIV-1 isolate. An additional tran
Background: Adeno-associated virus (AAV) vector has been widely used for gene therapy in a variety of preclinical studies. The virus has infected most of the population and never shown any pathogenic effects in humans. AAV vector which can integrate into the cellular DNA has been shown to confer long-term gene expressi
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA290)
Kent S, Zhao A, Dale CJ, Land S, Boyle D, Ramshaw I; S. Kent, Macfarlane Burnet Centre, Yarra Bend Rd, Fairfield 3078, Australia, Tel.: +61 392 822 175, Fax: +61 394 826 152, E-mail: kent@burnet.edu.au
Background: A preventive HIV vaccine would be a quantum advance on current efforts to control the HIV pandemic. While HIV protein vaccines have not shown encouraging efficacy and live attenuated vaccines are unsafe, both plasmid DNA and fowlpoxvirus (FPV) HIV vaccines can induce CTL responses in a proportion of outbred
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA291)
Cardinaud S, Rohrlich P, Langlade-Demoyen P, Firat H, Lemonnier F; S. Cardinaud, Institut Pasteur, Unite d'Immunite Cellulaire Antivirale, Dpt SIDA & Retrovirus, 28, rue du Dr Roux, 75724 Paris Cedex 15, France, Tel.: +33 1 45 68 88 63, Fax: +33 1 45 68 88 64, E-mail: cardinau@pasteur.fr
Background: It is conceivable that a rapid recruitment and expansion of specific HIV cytotoxic T cells (CTL) after exposure play an important role in protection against HIV infection. We have generated H2-class I negative HLA-B*0702 transgenic mice and used them for comparative evaluation of the immunogenecity of poten
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA292)
Robert-Guroff M, Patterson LJ, Robey FA, Muck A, Aldrich K, Richardson ES, Markham PD, Cranage M; M. Robert-Guroff, NIH, National Cancer Institute, 41 Library Drive, Building 41, room D804, Bethesda, MD 20892-5055, United States, Tel.: +1 301 496 2114, Fax: +1 301 496 8394, E-mail: guroffm@exchange.nih.gov
Background: We assessed immunogenicity and protective efficacy of a peptide polymer (peptomer), representing the SIV gp120 CD4 binding site. The peptomer mimics gp120 alpha-helical structure, binds CD4, and contains B- and T-cell epitopes. It should elicit broadly reactive, conformationally dependent antibody, and stro
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA293)
Matsuo K, Ohsu T, Kanekiyo M, Hamatake M, Hamano T, Honda M;;; K. Matsuo, JST AIDS Vaccine Project, NIH, DMSC, Ministry of Public Health, Tivanond Road, Nonthaburi 11000, Thailand, Tel.: +66 2 951 1485, Fax: +66 2 951 1486, E-mail: matsuo@dmsc.moph.go.th
Background: Safe and live recombinant vector-based vaccine has advantages for HIV/AIDS vaccine development and a consecutive immunization regimen also seems desirable for inducing long-lasting immunities against HIV-1. Moreover, highly conserved Gag antigen of HIV is one of the most appropriate candidate to induce HIV-
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA342)
Ramaley PA, French N, Kaleebu P, Gilks CF, Whitworth J, Hill AV;;; P.A. Ramaley, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, United Kingdom, Tel.: +44 1865 287 592, Fax: +44 1865 287 660, E-mail: pramaley@well.ox.ac.uk
Background: The host genetics of HIV-1 infection and disease progression has been intensively investigated in Caucasians but there have been few studies of sub-Saharan Africans. It is unknown whether polymorphisms which impact HIV-1 disease in Western populations will also play a similar role, or even be present, in Af
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA343)
Morris L, Trkola A, Ketas T, Bures R, Cilliers T, Maddon P, Montefiori DC, Moore JP; L. Morris, Private Bag X4, Sandringham, Johannesburg, 2131, South Africa, Tel.: +27 11 321 4232, Fax: +27 11 882 0596, E-mail: lynnm@niv.ac.za
Background: Entry of HIV-1 into cells is dependent on the interaction of the envelope glycoprotein with both CD4 and a coreceptor, most frequently CCR5. Agents that inhibit viral entry include small molecule inhibitors, antibodies and chemokines. Knowledge of the effectiveness of these compounds against subtype C virus
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA344)
Vicenzi E, Panina-Bordignon P, Poli G; E. Vicenzi, San Raffaele Scientific Institute, P2-P3 Laboratories, DIBIT, Via Olgettina n. 58, 20132, Milano, Italy, Tel.: +39 2 2643 4908, Fax: +39 2 2643 4908, E-mail: poli.guido@hsr.it
Background: CD4+ T cells may undergo functional polarization into Th1 or Th2 cells, secreting either IFN-g or IL-4, respectively. Early studies indicated that HIV replication was impaired in Th1, but not in Th2 or unpolarized T cell clones. Methods: Infection of Th1 or Th2 polarized or unpolarized (Th0) T cell clones o
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA345)
Shaunak S, Veryard C, Buttigieg K, Javan C; S. Shaunak, Imperial College School of Medicine, Hammersmith Hospital, Ducane Road, London. W12 0NN, United Kingdom, Tel.: + 44 208 383 2301, Fax: + 44 208 383 3394, E-mail: s.shaunak@ic.ac.uk
Background: Many opportunistic infections (OI) induce pro-inflammatory cytokine release and promote T cell activation in vitro. We investigated the effect of Pneumocystis carinii pneumonia ( PCP ), CMV and HSV on HIV-1 rep
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA346)
Cabana Sumsi M, Parera M, Clotet B, Martinez MA; M. Cabana Sumsi, Fundacic Irsicaixa, Hosp. Universitare Germans Trias i Pujol, Ctra del Canyet S/N, 08916 Badalona, Spain, Tel.: +34 934 656 374, Fax: +34 934 653 968, E-mail: mcabana@ns.hugtip.scs.es
Human immunodeficiency virus type 1 (HIV-1) resistance to antiretroviral drugs is the main cause of patient treatment failure. Despite the problems associated with interpretation of HIV-1 resistance testing, resistance monitoring should help the rational design of initial or rescue antiretroviral therapies. We have dev
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA347)
Rayner MM, Garber S, Logue K, Corbett J, Baker D, Lukac S, Powell D, Bacheler L, Erickson-Viitanen S; M. M. Rayner, DuPont Pharmaceutical Co., Experimental Station, E400/5255, Wilmington, DE 19880, United States, Tel.: +302-695-7385, Fax: +302-695-4083 or 302-571-1094, E-mail: marlene.m.rayner@dupontpharma.com
Introduction: Efavirenz (SUSTIVA(tm), DMP 266) is a potent NNRTI, which has demonstrated clinical efficacy in HAART regimens. Genotyping in efavirenz clinical trials has shown that in >90% of patients who fail therapy, a mutation encoding a substitution of K103N in the RT gene is predominant, conferring cross resistan
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA348)
Imamichi T, Berg S, Imamichi H, Metcalf JA, Falloon J, Lane HC; T. Imamichi, SAIC-Frederick, PO Box B, Bldg. 550, Rm. 126, NCI-FCRDC, Frederick, MD, 21702, United States, Tel.: +1 301 846 1910, Fax: +1 301 846 6762, E-mail: timamichi@nih.gov
Object: The purpose of the present study was to determine the impact of a novel deletion at codon 67 (del67) and a novel substitution at codon 69 (T69G) in replication fitness of these multiple drug resistance forms of HIV. Methods: Site-directed mutagenesis were utilized to construct a series of recombinant HIV varian
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA349)
Arion D, Sluis-Cremer N, Parniak M; D. Arion, Lady Davis Institute, McGill AIDS Centre, Jewish General Hospital, 3755 Cote Ste Catherine Road, Montreal, H3T 1E2, Quebec, Canada, Tel.: +(514) 340 8260 ext 5303, Fax: +(514) 340 7502, E-mail: d_arion@hotmail.com
Background: HIV-1 reverse transcriptase (RT) is a multifunctional enzyme, with both DNA polymerase and RNase H activities. While numerous inhibitors of RT DNA polymerase activity have been identified, very few inhibitors of RNase H activity have been described. We were the first group to identify a potent small molecul
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA350)
Wainberg MA; M.A. Wainberg, McGill University AIDS Centre, 3755 Cote Ste-Catherine Rd., Montreal, Canada, Tel.: +1 514 340 8307, Fax: +1 514 340 7537, E-mail: mdwa@musica.mcgill.ca
The M184V mutation in the reverse transcriptase (RT) gene of human immunodeficiency virus type 1 (HIV-1) is associated with high-level (i.e. §im1000 fold) resistance against 3TC as well as low-level resistance (i.e. 3-10 fold) against each of
Objective: To study the evolution and fitness of multidrug-resistant HIV-1 with an insertion of two amino acids between positions 68 and 69 of the RT gene and aa changes at positions 67 and 215 in an individual receiving intermittent therapy. Methods: 17-20 full-length molecular clones of RT from serum-derived viruses
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA404)
Bukrinsky M, Alfano M, Pushkarsky T, Poli G; M. Bukrinsky, The Picower Institute for Medical Research, 350 Community Drive, Manhasset, NY 11030, United States, Tel.: +1 516 562 94 38, Fax: +1 516 365 02 86, E-mail: mbukrinsky@picower.edu
Pertussis toxin (PTX) is a pentameric protein, which can be functionally divided into two (A and B) subunits. The A (active) protomer exhibits adenine diphosphate (ADP) ribosyltransferase activity responsible for ribosylation and inactivation of Gi-like proteins, whereas the role of the B (binding)-oligomer was initial
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA405)
Huang P, Sun Y, Chen H-C, Huang P, Lee-Huang S; P. Huang, American BioSciences, 8 Whittier Place, #7E, Boston, MA 02114, United States, E-mail: p.huang@rcn.com
Background: Lysozyme acts against bacterial/viral infection, tumor growth, and modulates host immunity. These combined effects distinguish lysozyme from other drugs. Recently, it was discovered that lysozyme contributes to the anti-HIV activity of b-core of hCG. This opens the way to an entirely new class of anti-AIDS
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA406)
Schneider J, Hahne J; J. Schneider, University of Freiburg, Department of Virology, Hermann-Herder-Str. 11, D-79104 Freiburg, Germany, Tel.: +49 761 203 65 88, Fax: +49 761 203 66 39, E-mail: schf@ukl.uni-freiburg.de
Background: The initiation of HIV-transcription is regulated by cellular proteins which bind to the enhancer region of the integrated provirus. Therefore recombinant proteins consisting of enhancer-binding and transcription repression domains can be envisaged as efficient intracellular repressors of HIV. In our model,
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA407)
Everall I, Trillo-Pazos G, Kandanearatchi A, Vyakarnam A, Eyeson J; I. Everall, Institute of Psychiatry, Kings College London, DeCrespigny Park, London, SE5 8AF, United Kingdom, Tel.: +44 171 848 04 41, E-mail: i.everall@iop.kcl.ac.uk
Background: Antiretroviral drug efficacy in HIV infected human brain has been scarcely tested. Clinical studies indicate that HAART can improve cognitive function, but it is unknown which antiretrovirals ameliorate HIV brain damage. Methods: To assess this we established an innovative human brain aggregate system. Each
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA408)
Rusconi S, La Seta Catamancio S, Citterio P, Bulgheroni E, Croce F, Galli M, Hirsch MS; S. Rusconi, University of Milan, Ospedale Luigi Sacco, Istituto di Malattie Infettive e Tropicali, via GB Grassi 74, 20157 Milan, Italy, Tel.: +39.02.390 42 676, Fax: +39.02.356 09 05, E-mail: rusconi@mailserver.unimi.it
Background: Antagonists of chemokine receptors CCR5 and CXCR4 are potential antretroviral agents. We studied the combined effects of a derivative of SDF-1beta, Met-SDF-1beta, and a modified form of RANTES, AOP-RANTES. Methods: Inhibitory effects were tested with or without the two fusion inhibitors at virus inhibitory
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA409)
Lapidot A, Litovchick A, Borkow G; A. Lapidot, Weizmann Institute of Science, Prof. Aviva Lapidot, Dept. Organic Chemistry, Weizmann Institute of Science, 76100 Rehovot, Israel, Israel, Tel.: +972-8-934-3413, Fax: +972-8-934-4142, E-mail: aviva.lapidot@weizmann.ac.il
Background: HIV Tat protein is a key factor of HIV transcription, an immunosuppresor, an activator of quiescent T cells for productive HIV-1 infection, a chemokine analog and an up-regulator of HIV-1 coreceptors expression. We have recently designed and synthesized a novel group of peptidomimetic compounds, aminoglycos
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA410)
Russell K, Sanchez J, Carcamo C, Negrete M, Blanco JC, Jimenez AG, Avila M, Martinez L, Serra M, Russi J, Alava A, Gianella A, Andrade R, Carr JK; K. Russell, Embajada Americana, c/o US NMRCD, Av. La Encalada Cuadra 17, Monterrico, Santiago de Surco, Lima, Peru, Tel.: +51 1 562 38 80, Fax: +51 1 561 30 42, E-mail: russell@namrid.sld.pe
Background: Genotypic differences may be reflected in antigenic differences; therefore, knowledge of circulating genotypes of HIV-1 becomes important as vaccine trials become a reality. The U.S. Navy Medical Research Center Detachment in Lima, Peru in collaboration with the Pan American Health Organization, respect
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA411)
Peeters M, Mboup S, Ndoyi-Mbiguino A, Koyalta D, Mulanga-Kabeya C, Mpoudi-Ngole E; M. Peeters, IRD Laboratoire retrovirus, 911 Avenue Agropolis, BP 5045, 34032 Montpellier Cedex 1, France, Tel.: +33-4 67 41 62 97, Fax: +33-4 67 61 94 50, E-mail: martine.peeters@mpl.ird.fr
Background:To identify and characterize HIV-1 viruses that circulate in west and west central africa, and to determine their relative prevalence. Methods: More than 1500 HIV-1 postive samples were characterized in the V3-V5 region of the envelope, by HMA(heteroduplex mobility assay) and/or sequencing.The samples were c
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA412)
Roques P, Souquiere S, Damond F, Couturier E, Farfara I, Dormont D, Simon F, Fleury H, Brun-Vezinet F; P. Roques, CEA, Service de Neurovirologie, B.P.6, Fontenay-aux-Roses, France, Tel.: +33 1 46 54 76 74, Fax: +33 1 46 54 77 26, E-mail: roques@dsvidf.cea.fr
Background: To study the HIV non B strains from the Observatoire des souches de VIH-1 en France to assess recombinations in a population of known date of infection. 2) To evaluate the impact of the recombination of viruses on epidemiological survey in terms of prevalence of anti-HIV drug resistant mutations in such a
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA413)
Cleghorn FR, Jack N, Carr JK, Edwards J, Mahabir B, Sill AM, McDanal CB, Connolly SM, Greenberg M, Goodman D, Bennetts R, O'Brien T, Weinhold K, Blattner WA, Bartholomew C; F.R. Cleghorn, Institute of Human Virology, 725 West Lombard St., MBC Building Rm., Baltimore, MD 21201, United States, Tel.: (410) 706-1941, Fax: (410) 706-1944, E-mail: sill@umbi.umd.edu
Background:The predominant risk behavior associated with HIV-1 spread worldwide is heterosexual activity, and non-Clade B viruses account for the majority of transmission. The epidemic of HIV-1 in Trinidad & Tobago and the Caribbean shares many features with such hetero
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA414)
Karamov E, Kornilaeva G, Pavlova T, Turgiev A, Nelson K; E. Karamov, Ivanovsky Institute of Virology, 16 Gamaleya Street, Moscow 123098, Russian Federation, Tel.: +7 95 190 3048, Fax: +7 95 190 2867, E-mail: karamov@invir.msk.su
Background: Although Russia is currently experiencing the early stage of HIV-1 epidemic, active spread of the virus among IDUs is dramatically changing the epidemiological situation. Methods: Sera from 2000 HIV-1-infected patients were tested in ELISA using a set of V3 peptides;
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrA415)
Williamson C, Swanstrom R, Morris L, Thomas R, Ping L-H, Pascual A, Johnston RE, Abdool Karim S; C. Williamson, SAIMR / UCT, SAIMR Virology, Department of Medical Microbiology, University of Cape Town, Observatory, South Africa, Tel.: +27-21-406 6127, Fax: +27-21-448 4110, E-mail: cwilliam@curie.uct.ac.za
Background: HIV-1 subtype C accounts for over 90% of infections in Southern Africa. This study aimed to identify subtype C isolates representative of viruses in Southern Africa, for use in the design of candidate vaccines. Methods: Samples were collected from 14 commercial sex workers in Kwazulu/Natal who had seroconve
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB275)
Dey SK, Pal NK; S.K. Dey, P-41/1, Nat Abar Pal Road, Howrah 71 11 05, India, Tel.: +91 33 651 34 64, Fax: +91 33 554 5741
Background: India , home to 3.5 million HIV +ives (Sero +vity rate 25.3/1000- Oct. 99 among reported 89,840), also has high TB infection rates (50% in adults). As TB is the commonest opportunistic infection (around 60%) among HIV +ives, a comparative study of disease pattern (among sero -ive and sero +ive subjects) is
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB276)
Lugada E, Gilks C, Nakiyingi JS, Whitworth JA, Neil F, Watera C, Mukasa-Monico S, Antivelink L; E.Lugada, The AIDS Support Orginasation, PO Box 12777, Kampala, Uganda, Tel.: +256 77 507 410, Fax: +256 41 321 137, E-mail: ericlugada@yahoo.com
Back ground: Tuberculosis (TB) preventive therapy can reduce HIV related TB. Successful implementation in low income settings presents many problems. We set out to asses the operational aspects of a six month daily course of isoniazid (INH) therapy in HIV-1 , purified protein derivative (PPD) skin test positive attendi
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB277)
Spradling P, McLaughlin S, Drociuk D, Ridzon R, Pozsik C, Onorato I;;; P. Spradling, Centers for Disease Control & Prevention, 1600 Clifton RD, Mailstop E-10, Atlanta, GA 30333, United States, Tel.: +1 404 639 53 10, Fax: +1 404 639 89 59, E-mail: pps9@cdc.gov
Background: Use of rifamycins is limited by drug interactions in those receiving highly active antiretroviral therapy (HAART). Substitution of rifabutin (Rfb) for rifampin is recommended for treatment of active tuberculosis (TB) and when using a 2-month rifamycin/pyrazinamide (2RZ) regimen for latent M.
Background: Following results of the Cote d Ivoire cotrimoxazole prophylaxis study in HIV positive TB patients, an operational research study was launched in a rural district of Malawi with the objective of verifing the possible feasibility of implementing cotrimoxazole prophylaxis within a district set-up, and its pos
Background: The UNAIDS HIV Drug Access Initiative (DAI) is a pilot program intended to increase the access to AIDS care and drugs, including antiretroviral (ARV) drugs, in developing countries. We analyzed the sustainability of ARV therapy within the DAI in Uganda . Methods: Patients (pts) who accessed
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB295)
Djomand G, Roels TH, Coulibaly M, Diomande F, Ebah L, Nkengasong J, Aka R, Monga B, Maurice C, Bissagnene E, Wiktor SZ, Chorba T; G. Djomand, Projet Retro - CI, 01 BP 1712, Abidjan 01, Cote D'ivoire, Tel.: +225 212 541 11, Fax: +225 212 429 69, E-mail: agd3@cdc.gov
Background: In August 1998, a pilot program was started by UNAIDS and the Cote d Ivoire Ministry of Health (MOH) to improve access to drug therapy for HIV infection, including antiretrovirals. Objective: To describe the types of antiretroviral regimens prescribed and the virologic and immunologic response to these the
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB296)
Gilada I, Bodhare S; I. Gilada, Unison Medicare & Research CentreMumbai 400007, India, Tel.: +91-22 306 16 16, Fax: +91 22 300 00 16, E-mail: gilada@usa.net; ihoaids@vsnl.com
Background: Though ARV have produced dramatic impact on morbidity/mortality of PLWHA in industrialised countries,the situation in resource-poor settings is grim as ARV cost is prohibitive.They are gullible and exploited by fake claimants.Some manage to collect ARV costs through family support/borrowings. Despite counse
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB297)
Sow PS, Laurent C, Gueye PM, Faye-Niang MA, Ciss M, Mboup S, Badiane S, Delaporte E, Ndoye I; P.S. Sow, Clinique des Maladies infectieuses - Chu de Fann, BP 5035, Dakar Fann, Senegal, Tel.: +221 825 25 47, Fax: +221 825 36 95, E-mail: salifsow@telecomplus.sn
Objective: To describe the clinical effectivness of the antiretroviral therapy (ARV) in a limited resources context . Methodology: before instituting antiretroviral therapy in Senegal , the preconditions were defined by a medical technical committee. A medical assessment is conducted for each patient before ARV therap
Objective: To determine the prevalence of ARV drug-resistant HIV-1 strains among patients treated with ARV in Cote d Ivoire . Methods: We selected all patients (n = 68) with a history of current or past ARV therapy who presented between August 1998 and April 1999 for inclusion in the UNAIDS-sponsored Drug Access Initi
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB299)
Jayaweera D, Scerpella E, Lalanne R, Asthana D, Kolber M; D. Jayaweera, University of Miami School of Medicine, 901, NW 17th Street, Suite D (D90A), Park Plaza East, Miami FL 33136, United States, Tel.: +1 305 243 4598, Fax: +1 305 243 4037, E-mail: djayawee@med.miami.edu
Background: Inner-city minority patients with substance abuse have multiple problems that contribute to poor adherence to antiretrovirals. Simple and tolerable but potent regimens may help to improve adherence and outcomes. We evaluated a 2-drug regimen of RIT+IDV (without NRTIs/NNRTIs) in patients with advanced diseas
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB300)
Lunardi-Iskandar Y, Bryant J; Y. Lunardi-Iskandar, Institute of Human Virology, Basic Science, Univ. Md. Biotech Institute, 725 W. Lombard Street Rm N456, Baltimore, Md 21201, United States, Tel.: +1 410 706 09 96, Fax: +1 410 706 00 51, E-mail: lunardi@umbi.umd.edu
Background: Non Hodgkin lymphoma `NHL is one the most common AIDS-malignancies. They are often EBV-negative and the incidence occurs in 3-6% of NHL in HIV-1 infected individuals. The pathogenesis of NHL is not yet completely understood. We have developed a HIV-1 transgenic mouse model with spontaneous B-cell lymphomas.
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB301)
Sitas F, Pacella-Norman R, Carrara H, Patel M, Ruff P, Bezwoda W, Sur R, Jentsch U, Hale M, Rowji P, Saffer D, Connor M, Bull D, Newton R, Beral V; F. Sitas, Cancer Epidemiology Unit, National Cancer Registry, c/o South Afrian Institute for Medical Research, PO Box 1038, Johannesburg, 2000, South Africa, Tel.: +27 11 489 91 71, Fax: +27 11 489 91 52, E-mail: freddys@mail.saimr.wits.ac.za
Sitas F(1), Pacella Norman R(1), Carrara H(1), Patel M(2), Ruff P(2), Bezwoda W(2), Sur R(2), Jentsch U(3), Hale M(3), Rowji P(2), Saffer D(2), Connor M(2), Bull D(4), Newton R(4), Beral V(4).1 Cancer Epidemiology Unit, National Cancer Registry SAIMR, P.O. Box 1038, Johannesburg, 2000.2 Faculty of Health Sciences, Univ
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB302)
Renato M, Mongiovetti M, Vaccher E, Nasti G, Fasan M, Mena M, Di Gennaro G, Schioppa O, Tirelli U; M. Renato, Policlinico San Matteo, Istituto Malattie Infettive, Via Taramelli 5, 27100 Pavia, Italy, Tel.: +39 038 250 2959, Fax: +39 038 250 2959, E-mail: rmaserati@smatteo.pv.it
Objective: To determine the efficacy of HAART alone in the treatment of slow-proliferating Kaposi s sarcoma (KS). Methods: A prospective study was started in June 1997 to enroll HIV+, HAART-naive patients (pts) with KS (stage I to III, NYU). Enrolled pts were evaluated at baseline and then at fixed time points for the
Background: There are few studies focusing on the effect of HAART on the response to treatment and overall survival (OS) in AIDS-related NHL. We analyzed the influence of HAART on clinical and biological features, response to treatment and OS in a series of 57 patients (pts) with AIDS-related NHL treated with CHOP bet
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB304)
Blumberg HM, King MD, O'Daniels CM, Larsen NM, Reznik DA; H. M. Blumberg, Emory University, Division of Infectious Diseases, 69 Butler Street, Atlanta, GA 30303, United States, Tel.: +404-616-6145, Fax: +404-880-9305, E-mail: hblumbe@emory.edu
Introduction: Since the introduction of highly active antiretroviral therapy (HAART), we have recognized with increasing frequency the development of oral Human Papilloma Virus ( HPV ) infection among HIV+ patients receiving care at an urban oral health center (OHC).
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB305)
Moscicki A-B, Houser J, Ma Y, Murphy D, Wilson C; A.-B. Moscicki, University of California, San Francisco, 3333 California Street, Suite 245, San Francisco, CA 94118-0503, United States, Tel.: +1 415 476 5139, Fax: +1 415 502 4858, E-mail: annam@itsa.ucsf.edu
Background: Adolescents, in general, have not been regarded at high risk for anal human papillomavirus ( HPV ) associated precancers and cancers. We examined the association between anal HPV infection, squamous intra-epithelial lesions (SIL), and HIV status in adolescents and examined risk factors for anal SIL.
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB352)
John G, Bird T, Overbaugh J, Nduati R, Mbori-Ngacha D, Dong T, Rostron T, Kostrikis L, Kreiss J, Rowland-Jones S; G. John, University of Washington and University of Nairobi, University of Washington, Box 359909, Seattle, WA 98195, United States, Tel.: +1 206 731 28 22, Fax: +1 206 731 24 27, E-mail: gjohn@u.washington.edu
Background: Macrophage-tropic strains of HIV-1 utilize the CCR5 coreceptor for infection of cells. Mutations in the promoter region of CCR5 may result in effects on HIV-1 pathogenesis and transmission. Methods: We evaluated the effect of 4 polymorphisms in the CCR5 promoter region on maternal HIV-1 plasma viral load, m
Background: The mechanism of HIV vertical transmission is unclear. It can occur in utero, through breast-feeding and at birth, possibly by contact with cervico-vaginal secretions. This study is based on the following working hypothesis: 1) Genital shedding increases the risk of perinatal infection of the infant, 2) pla
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB354)
Wiktor SZ, Leroy V, Ekpini ER, Alioum A, Karon J, Msellati P, Hudgens M, Meda M, Greenberg AE; S. Z. Wiktor, Centers for Desease Control and Prevention, Atlanta, United States, Tel.: +404 639 6100, Fax: +404 639 4268, E-mail: szw0@cdc.gov
Objective: To assess the 24-month efficacy of a short course of oral zidovudine (ZDV) administered in late pregnancy to prevent mother-to-child HIV-1 transmission in a breast feeding population in West Africa. Methods: Data were pooled from two clinical trials: DITRAME conducted in Abidjan,
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB355)
Gray G, McIntyre J, Jivkov B, Schorn M, Lala S, Reynolds L, Ledeine J-M, Van Beek A, Schnittman S; G. Gray, Perinatal HIV Research Unit, Maternity Sector, Chris Hani Baragwanath Hosp., Old Potch Road, Soweto 2013, South Africa, Tel.: +27-11-938-3984, Fax: +27-11-938-3973, E-mail: gray@pixie.co.za
Background: The rapid implementation of the ACTG 076 regimen in resource-rich countries has led to dramatic decreases in MTCT and pediatric HIV. However, these results have not been extended to the developing world where the majority of MTCT occurs because of the high cost of intervention and the logistics of a complex
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB356)
McIntyre J; J. McIntyre, Perinatal HIV Research Unit, Chris Hani Baragwanath Hospital, Soweto, RSA, South Africa, Tel.: 27-11-938-3984, E-mail: rcurry@rdg.boehringer-ingelheim.com
Background: The SAINT Study was conducted in South Africa to compare the efficacy of a short course of NVP with a short course of ZDV+ 3TC for prevention of MTCT of HIV. The assessment of safety is critical for MTCT prophylaxis. Methods: SAINT is an ongoing, randomized, open label, multicenter tria
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB357)
Francisco P, Javier E, Rosario S, Jose Maria C, Juan F, Caridad R, Jose L, Vicente A, Jose Adolfo O; P. Francisco, Hospital Marina Baixa, Partida Galande No 5, 03570 Villajoyosa, Alicante, Spain, Tel.: +34 96 685 98 47, Fax: +34 96 685 99 00, E-mail: pasquau_fra@gva.es
Background: Leishmania is a common infection in patients infected with HIV living in Mediterranean areas. We describe the clinico-epidemiological characteristics, determinants for relapse and survival of HIV and Leishmania infection in a large cohort of patients from a Spanish Mediterranean area. Methods: Retrospective
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB358)
Giancola ML, Tartaglione T, Ammassari A, Settecasi C, Cingolani A, Larussa D, Murri R, De Luca A; M. L. Giancola, Catholic University, Rome, Clinica delle Malattie Infettive, L.go Gemelli, 8, Roma, Italy, Tel.: +39 06 301-549-45, Fax: +39 06 305-45-19, E-mail: iclimi@rm.unicatt.it
Objective: to establish the predictive value of clinical, neuroradiological, virologic and immunologic variables on the survival of AIDS-related PML. Methods: Retrospective analysis of clinical data collected according to pre-established protocol (demographics, neurological examination, Karnofsky, CD4, antiretroviral t
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB359)
Perez H, Zala C, Ochoa C, Puente S, Vazquez M, Cahn P; H. Perez, Hospital Fernandez, Angel Peluffo 3932 (1202), Buenos Aires, Argentina, Argentina, Tel.: +54 11 4981-7777, Fax: +54 11 4982-4024, E-mail: pcahn@huesped.org.ar
Introduction: Immune reconstitution following control of viral replication suggests that maintenance therapy (MT) for CMV retinitis can be discontinued. In view of the absence of controlled studies, clinical reports assessing clinical outcome of HIV patients with CMV retinitis are needed. Objectives: To determine the
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB360)
Abgrall S, Matheron S, Le Moing V, Dupont C, Costagliola D; S. Abgrall, Inserm SC4, Faculte Saint-Antoine, 27 Rue Chaligny, 75 571 Paris Cedex 12, France, Tel.: +331 447 384 59, Fax: +331 430 739 57, E-mail: abgrall@b3e.jussieu.fr
Background: To assess incidence and risk factors for PCP recurrence in a cohort of HIV-patients treated with HAART. Methods: The FHDH is a prospective cohort of 70224 subjects. This study included the 485 patients treated with HAART while on PCP maintenance prophylaxis after a first episode observed between 1 January
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB361)
Hughes-Gibbs B; B. Hughes-Gibbs, Kerux/Mohau, PO Box 75222, Lynnwood Ridge, 0040, Pretoria, South Africa, Tel.: +27 12 318 6729, Fax: +27 12 318 6729, E-mail: ithay@kalafong.up.ac.za
The Care Umbrellas of Kalafong is a unique series of linked modular care and prevention programmes in support of people Infected or Affected by AIDS. The programmes were designed by multi-disciplinary teams of professional and volunteer Health, Welfare, Education, Early Child Development specialists and general care gi
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB362)
Sentumbwe S, Nakazi SD; S. Sentumbwe, Centre for peace research PO Box 127 85, Kampala, Uganda, Tel.: +256 41 34 00 84, Fax: +256 41 34 00 84
Back ground: To identify and document innovative and new creative approaches to AIDS care and counseling that have resulted into high quality programming for People Living With HIV/AIDS (PLWA). Methods: Multiple data collection methods were used which included; i) Key informant interviews with program managers ii) Focu
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB363)
Hall G, Kong Bun N; G.Hall, Sihanouk Hospital Center of HOPE, PO Box 2318, Phnom Penh 3, Cambodia, Tel.: +855 23 882 484, Fax: +855 23 882 485, E-mail: sihosp@bigpond.com.kh
Issues: HIV/AIDS is devastating Cambodia , a very poorly resourced country still recovering from years of war. Increased awareness to prevent new infections and a cost effective care and support strategy is needed to meet the growing demands of the epidemic. Project: Staff at the Sihanouk Hospital Center of HOPE (SHCH)
Issues: Home based care for people living with HIV/AIDS is a major component of holistic and continuum of care as well as to utilize hospital resources appropriately and efficiently. To establish the service is complex and need inter-sectoral cooperation. Description: The explosive spread of HIV infection in Chiang Ra
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB365)
Silva C, Santos-Filho ET, Nascimento C; C. Silva, AV Rio Branco 135/709, Rio De Janeiro 20040-006, Brazil, Tel.: +552 151 839 93, Fax: +552 151 819 97, E-mail: gpvrj@pelavidda.org.br
Problem: Along the two years of a local based home care program - the Rio Buddy Project (RBP) - it has been registered a growing demand for psychological or psychiatric specialized services by the clients of the project. In this period, 34% of the clients have had this demand; among them 4% of the total clients are che
Issue: Integration of HIV/AIDS prevention into home care programme has a double effect over care and support. Description: The AIDS integrated programme of the Ndola Catholic Diocese, Zambia , has integrated AIDS prevention activities into the home care programme. 750 volunteers and 28 community nurses- all care giver
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB400)
Anastos K, Barron Y, Weiser B, Hessol N, Young M, Cohen M, Miotti P, Augenbraun M, Levine A, Munoz A; K. Anastos, Albert Einstein College of Medicine, 41 Lewis Parkway, Yonkers, NY 10705, United States, Tel.: +1 914 476 8675, Fax: +1 914 476 8677, E-mail: kanasto@aol.com
Objectives: To determine the factors associated with progression to AIDS or death with HAART initiation (HAART) at different immunologic, virologic and clinical stage. Methods: In 893 HIV infected women in the Women s Interagency HIV Study with a known date of initiating HAART (?6 mo). Time from HAART to AIDS and death
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB401)
Quigley M, Mwinga A, Hosp M, Lisse I, Fuchs D, Porter J, Godfrey-Faussett P; M. Quigley, London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, United Kingdom, Tel.: +44 0171 927 2165, Fax: +44 0171 436 4230, E-mail: maria.quigley@lshtm.ac.uk
Objective: To compare HIV progression and mortality rates in men and women in a cohort of HIV infected Zambian adults. Methods: Between Aug 1992 and June 1994, 1053 HIV infected adults were enrolled into a randomised trial of preventive therapy for TB. Subjects were seen every 3 months and followed until death, or cens
Background: Initial HIV-1 plasma RNA level (VL) after seroconversion (SC) predicts progression to AIDS in men; this has not been well-studied in women. Recent studies have demonstrated lower VL in women than men at the time of SC, and sex differences in HIV-1 viral dynamics. We measured plasma VL among all HIV-1 seroco
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB403)
El-Sadr W, Bebchuk J; W. El-Sadr, Harlem Hospital Center, Division of infectious Deseases, Room 3101A, 506 Lenox Ave, New York 10037, United States, Tel.: +212 939 29 50, Fax: +212 939 29 68, E-mail: wme1@columbia.edu
Objective: Controversy remains regarding outcome of antiretroviral therapy (ART) among women (W) compared to men (M). We assessed risk of progression of HIV disease or death (PROG) among patients (pts) enrolled in randomized CPCRA studies in past decade. These studies were grouped based on the type of
Background: Patient adherence to HAART is crucial to the effectiveness of the regimen. Inner-city patients (IVDU and minorities) are consistently identified as populations at high risk of nonadherence to HAART. The study hypothesis is that inner-city patients do not take HAART as prescribed and nonadherence leads to vi
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB417)
Carmona A, Knobel H, Guelar A, Grau S, Mateu-de Antonio J, Lopez-Colomes JL, Saballs P; A. Carmona, IMAS, Hospital del Mar, Passeig Maritim 25-29, 08003 Barcelona, Spain, Tel.: +34 93 221 04 16, Fax: +34 93 221 04 16, E-mail: 91422@imas.imim.es
Objective: To assess which factors influence on the survival of HIV infected patients treated with HAART. Method: The study was carried out in a 450-bed university hospital in Barcelona ( Spain ). Patients included were those infected by HIV that started HAART (2 nucleoside analogues + 1 protease inhibitor) between Jun
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB418)
Merchan-Hamann E, Vale MS; E. Merchan-Hamann, University of Brasilia, Campus Universitario - Asa Norte, CEP: 70.910-900, DF, Brazil, Tel.: +55 061 274 70 22, Fax: +55 061 274 70 22, E-mail: hamann@unb.br
Background: In Brazil , standard AIDS therapy is provided free by the Ministry of Health. A case-control study for predictors of treatment abandonment was carried out in the main AIDS public facility of Taguatinga, Federal District, in 1999. Methods: Cases were defined as AIDS patients who abandoned standard treatment
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB419)
Hogg R, Yip B, Chan K, O'Shaughnessy M, Montaner J; R. Hogg, BC Centre for Excellence in HIV/AIDS, 608-1081 Burrard St, Vancouver BC, Canada, Tel.: +1 604 631 5516, Fax: +1 604 631 5464, E-mail: ewood@hivnet.ubc.ca
Objective: To characterize the response to antiretroviral (ARV) therapy among participants enrolled in a population-based anti-HIV drug treatment program in British Columbia (BC). Methods: In BC antiretroviral therapies are distributed free of charge according to specific therapeutic guidelines. Study subjects were ARV
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB420)
Mulindwa M, Kiyimba W, Wanyana S, Kondee Pool C, Byamukama A, Mugisha E, Kityo C; M. Mulindwa, Joint Clinical Research Centre, P. O. Box 10005, Kampala, Uganda, Tel.: +256-41-270622, Fax: +256-41-342632, E-mail: JCRC@STARCOM.CO.UG
Background: In Uganda , out of approximately 2 million people infected with HIV, 850 of these are registered as taking ARV therapy. Of the 850 individuals, 550 of them are registered at the Joint Clinical Research Centre (JCRC). JCRC is one of the facilities selected by UNAIDS to carry out
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrB421)
Mannerheimer S, Friedland G, Matts J, Chen L, Child C, MacArthur R, Kostman J, Brizz B, Chesney M; S. Mannerheimer, Columbia University, Harlem Hospital Center, 506 Lenox Avenue, Room 3101A, New York 10037, United States, Tel.: +1 212 939 2948, Fax: +1 212 939 2968, E-mail: sbm20@columbia.edu
Objectives: To determine if self-reported adherence (adh) with antiretroviral (AR) therapy correlates with treatment outcome as measured by HIV RNA plasma level and CD4 count and if adh levels are sustained over time among participants in two multi-centered national clinical trials. Methods: Participants (pts) in CPCRA
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC306)
Samayoa B, Martinez M, Velasquez T, Fuentes Urrutia Z, Ramirez JM; B. Samayoa, Asociacion de Salud Integral, 1a Avenida 11-19 Zona 1, Guatemala 01001, Guatemala, Tel.: +502 220 8506, Fax: +502 251 6531, E-mail: asiagpcs@guate.net
Background: HIV counselling and testing services at our clinic covers more than the 60% of the AIDS cases nationally reported. In spite of this we determined that only the 60% of the clients return for their results. Based on this fact we decided to improve our traditional method of HIV testing by using a rapid test. O
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC307)
Farquhar C, Mbori Ngacha D, Bosire R, Nduati R, Kreiss J, John G; C. Farquhar, University of Washington, c/o Grace John, Microbiology Annex, P.O. Box 19676, University of Nairobi, Nairobi, Kenya, Tel.: +254 2 719 604, Fax: +254 2 722762, E-mail: cfarq@ratn.org
Background: Pregnant HIV-1 seropositive women often require the financial and emotional support of their partners to access interventions to decrease transmission of HIV-1 to their infants. Determinants of partner notification among HIV-1 seropositive pregnant women are poorly defined. Methods: Pregnant women attending
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC308)
Maman S, Mbwambo J, Hogan M, Kilonzo G, Weiss E; S. Maman, JHU SHPH Dept International Health, 615 North Wolfe Street Room E7141, Baltimore MD, United States, Tel.: +1 4104 315 036, Fax: +1 4104 315 036, E-mail: smaman@jhsph.edu
Background: In view of the ever-increasing and overlapping epidemics of HIV and violence against women in sub-Saharan Africa, there is an urgent need for applied research to develop interventions that respond to both problems. To examine the intersections between HIV and violence, a study supported by Fogarty Internati
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC309)
Mhazo M, Moyo S, Von Lieven A, Maponga C, Bassett MT; M. Mhazo, Zimbabwe AIDS Prevention Project, 103 Rotten Row, Kopje, Harare, Zimbabwe, Tel.: +263 4 770 610, Fax: +263 4 749 865, E-mail: miriam@zappuz.co.zw
Issues: Lower cost anti-retroviral regimens may make feasible government programmes for reduction of mother to child HIV transmission in poor countries, but expansion of HIV counselling and testing poses a substantial challenge. Use of community lay volunteers may offer an alternative to creation of a new professional
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC310)
Mutemi R, Forsythe S, Arthur G; R. Mutemi, National AIDS and STD Control Programme, PO Box 19361, Nairobi, Kenya, E-mail: steveforsythe@yahoo.com
Background: Voluntary counselling and testing (VCT) has been shown to be effective in limiting the transmission of HIV. In Kenya s most recent DHS, 63% of adults indicated a willingness to be tested for HIV. However, VCT is available in only a limited number of locations. Therefore this economic analysis was performed
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC311)
Lansky A, Lehman JS, Gatwood J, Hecht F, Fleming PL; A. Lansky, 1600 Clifton Road ( MS -E47 ), Atlanta, Georgia 30333, United States, Tel.: +1 404 639 20 50, Fax: +1 404 639 20 50, E-mail: allo@cdc.gov
Backgound: On January 1, 1998 name-based HIV surveillance was implemented in New Mexico. We assessed self-reported HIV testing history, beliefs about confidentiality, and knowledge of HIV reporting laws among persons at risk for HIV infection before and after implementation. Methods: The HIV Testing Survey (HITS) was a
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC312)
Van der Veen F, Joyce N; F. Van der Veen, EC/NACOP-Ministry of Health, P.O. Box 22331-Bachbrecht, Windhoek, Namibia, Tel.: +264 61 203 21 98, Fax: +264 61 22 41 55, E-mail: nacp@iafrica.com.na
Objectives: To estimate annual cost of the introduction of post exposure prophylaxis (PEP) at the Windhoek Central Hospital Complex WCHC and to make projections for the annual cost of nation-wide introduction of PEP using different scenarios. Methods: Existing reports on sharp injuries, which occurred during the perio
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC313)
Durand Zaleski I; I. Durand Zaleski, Hopital Henri-Mondor, 51, Avenue du Mal de Lattre de Tassigny, 94010 Creteil, France, Tel.: +33 149 813 674, Fax: +33 149 813 697, E-mail: isabelle.durand-zaleski@hmn.ap-hop-paris.fr
Objective: Subcutaneous injections account for an increasing share of total needlestick injuries. The objective was to document the cost and costs savings related to the use of protective devices. Methods: We estimated the frequency of needlestick injuries attributable to subcutaneous injections from both published and
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC314)
Benais J, Miara A, Brion S, Delaitre D, Werson P, Soussy A, Garnier M; Jean-PierreBenais, Hospital Jean-Verdier Av du 14 Juillet, Service des Urgences Medico-judiciaires, 931 43 Bondy, France, Tel.: +33 1 4802 6559, Fax: +33 1 4802 6557, E-mail: jean-pierre.benais@jvr.ap-hop-pairs.fr
Background: A procedure for treating sexual assault in the Paris region has been in operation since June 1999. It is based on a collaboration between referring doctors from different emergency medico-legal centre (5) including 6 million residents. Operating 24 h/24 h these units have received 750,000 victims in 1999 an
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC315)
Friedman RK, Rodrigues J, Fernandes MN, Moreira IR, Schechter M, Harrison L; R.K. Friedman, Projeto Praca XI - HIVNET/Brazil, Brazil, Tel.: +(55) 021 5701120, E-mail: Mark5@zipmail.com.br
Background: Post-exposure chemoprophylaxis is a widely-used intervention for the prevention of HIV infection, particularly in the occupational setting. However, no data are available on the potential effectiveness of post-exposure chemoprophylaxis for the prevention of sexual transmission of HIV. The Post-Sexual-Exposu
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC316)
Rey D, Den Diane MK, Moatti JP; D. Rey, Regional Centre for Disease Control, 23 rus stalislas Torrents, 13006 Marseille, France, Tel.: +33 491 598 906, Fax: +33 491 598 918, E-mail: rey@marseille.inserm.fr
Issues: Post exposure prophylaxis (PEP) after occupational exposure is available, promoted and widely prescribed in most industrialised countries. With regard to the probability of HIV transmission by certain sexual or drug exposure, prophylaxis should be also considered after non occupational exposure. However impleme
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC317)
de Waal N, Cotton MF; N. de Waal, Dept Paediatrcs and Child Health, Dept Paediatrics and Child Health, Tygerberg Hospital, Parow, 7295, South Africa, Tel.: +27 219 384 538, Fax: +27 21 938 9138, E-mail: steve.ship@yebo.co.za
Introduction: Illegal dumping of medical waste occurs commonly in South Africa .Little information on management and outcome of children exposed are available. Description of incident: On 15 Sept 1999 44 children (median age 9.7 y) presented after a mass exposure incident. Used needles and syringes had been discarded
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC367)
Babiker A, Pezzotti P, Walker S, behalf of the CASCADE Collaboration on; A. Babiker, MRC Clinical Trials Unit, 222 Euston Road, London, NW1 2DA, United Kingdom, Tel.: +44 20 7670 4719, Fax: +44 20 7670 4818, E-mail: agb@ctu.mrc.ac.uk
Objectives: Previous studies have suggested that individuals with similar CD4 count and different time from seroconversion have similar rates of progression to AIDS. We evaluated whether there was a residual effect of time from seroconversion on progression to AIDS from specific CD4 count levels. Methods: Pooled data o
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC368)
Learmont J, Birch M-R, Deacon N, Sullivan J; J. Learmont, Australian Red Cross Blood Service-NSW, 3/131 Clarence st, Sydney 2000, NSW, Australia, Tel.: +61 2 9229 43 00, Fax: +61 2 9229 44 79, E-mail: jlearmont@arcbs.redcross.org.au
Background: The SBBC were infected between 1981 and 1984 with a strain HIV-1 that has a deletion in the nef/LTR region. We here examine the different responses to infection between members of the SBBC that have emerged after long term infection. Methods: Analysis of HIV progression markers in members of the SBBC to 31
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC369)
Porter K; K. Porter, MRC Clinical Trials Unit, 222 Euston Road, London NW1 2DA, United Kingdom, Tel.: +44 20 767 047 15, Fax: +44 20 767 048 15, E-mail: k.porter@ctu.mrc.ac.uk
Objective: to compare estimates of changes in HIV survival over time derived from seroconverter and prevalent cohorts. Design/ Methods: using CASCADE pooled data from seroconverter cohorts, we examined the relative risk of death from HIV seroconversion by calendar time at risk from 1 January 1991. We repeated the anal
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC370)
Geskus R;;; R. Geskus, Municipal Health Service, Nieuwe Achtergracht 100, 1018 WT Amsterdam, Netherlands, Tel.: +31 20 555 5524, Fax: +31 20 555 5533, E-mail: rgeskus@gggd.amsterdam.nl
Background: In many HIV/AIDS cohort studies, seroconverters do not provide enough power to study natural history in case of small size effects. Often, prevalent cases constitute a substantial part of the study population, but including them requires an unbiased estimate of their date of seroconversion (sconv). Methods:
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC371)
Balotta C, Mazzucchelli R, Corvasce S, Facchi G, Dehy L, Velleca R, Mazzucchelli R, Corvasce S, Facchi G, Dehy L, Velleca R, Saporetti G, Moroni M, Galli M, Saporetti G, Moroni M, Galli M; C. Balotta, University of Milan, Institute of Infectious and Tropical Diseases, 'L. Sacco' Hospital, via G. B. Grassi, 74, 20157 Milan, Italy, Tel.: +39 02 382 00 319, Fax: +39 02 356 66 44, E-mail: claudia.balotta@unimi.it
Background: Conflicting data regarding the role of CCR5, CCR2 and SDF1 genes in delaying HIV-1 disease progression prompted us to study the prevalence of CCR5-D32, CCR2-64I and SDF1-3 A mutant alleles in Long-Term Nonprogressors (LTNPs) and subjects with a typical course of the disease (TPs). Methods: 77 LTNPs, 112 TPs
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC372)
Robain M, Boufassa F, Persoz A, Hubert J-B, Meyer L; M. Robain, Hopital Bicotre INSERM, 78 rue du general Leclerc, Le Kremlin Bicotre, 94276, France, Tel.: +33 1 45 21 23 65, Fax: +33 1 45 21 20 75, E-mail: robain@vjf.inserm.fr
Background: The influence of Cytomegalovirus seroconversion as a co-factor of HIV-1 disease progression remains controversial. Moreover, few cohorts of HIV-infected patients have monitored CMV serology over a long follow-up. We studied the role of a CMV seroconversion occurring after HIV seroconversion on progression
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC422)
Wawer MJ, Gray RH, Sewankambo NK, Serwadda D, Quinn TC, Lutalo T, Wabwire-Mangen F, Li C; M. J. Wawer, 60 Haven Ave., Floor B-2, New York, NY 10032 USA, United States, Tel.: +212-304-5278, Fax: +212-304-5272, E-mail: epm10@columbia.edu
Background: We assessed the effect of HIV-1 serum viral load on the rate of HIV transmission per act of heterosexual intercourse in HIV discordant couples. Methods: Monogamous HIV-1 discordant couples were retrospectively identified within a population-based trial of STD Control for AIDS Prevention, conducted between 1
Background: Male-to-female (M-to-F) HIV transmission is more efficient than female-to-male (F-to-M) in industrialized countries. We examined gender-specific transmission rates among HIV discordant couples in Uganda , adjusting for viral load. Methods: 415 HIV discordant couples were identified in a population based stu
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC424)
Robson B, Smith T-L, Cotton M, Engelbrecht S, Orth H, Schaaf S, Dobbels E, Leibrandt B, Janse van Rensburg E; B. Robson, Dept. of Medical Virology, Department of Medical Virology, PO Box 19063, Tygerberg 7505, South Africa, Tel.: +27 21 938 93 54, Fax: +27 21 938 93 61, E-mail: se1@gerga.sun.ac.za
Background: HIV infection in children is acquired mainly through vertical transmission. A few sporadic cases of horizontal transmission in the household involving children have been reported in the USA and Europe. In this study we report on the transmission of HIV-1 between 2 siblings. Methods: The index case (child A)
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC425)
Porco T, Charlebois E, Page-Shafer K, Osmond D; T. Porco, San Francisco Department of Public Health, 25 Van Ness Avenue, Suite 710, San Francisco, California 94102, United States, Tel.: +1 415 554 9037, Fax: +1 415 431 7029, E-mail: tcporco@mathepi.com
Background: We estimated the per-partnership infectivity of HIV using data from the San Francisco Young Men s Health Study (described in Am J Publ Hlth 84:1933). Our results update earlier per-partnership infectivity studies based on the San Francisco Men s Health Study (Grant et al., J Inf Dis 156:189, and Samuel et
Backgound: To elucidate the risk factors and their interaction s association with sexual transmission of HIV-1, a cross-sectional case-control study was conducted among married heterosexual men infected with HIV-1/AIDS in Taiwan . Methods: Blood samples and questionnaires have been collected from 858 (776 males and 72
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC427)
Moscicki A-B, Ma Y, Holland C, Vermund S; A.-B. Moscicki, University of California, San Francisco, 3333 California Street, Suite 245, San Francisco, CA 94118-0503, United States, Tel.: +1 415 476 5139, Fax: +1 415 502 4858, E-mail: annam@itsa.ucsf.edu
Background: It has been suggested that ectopy is a risk for HIV acquisition. Although ectopy is frequently found in adolescents, the association between ectopy and HIV status has not been examined in this age group. The objective of this study was to examine the association between ectopy and HIV status in adolescent g
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC428)
Morgan D, Muwonge R, Mahe C, Whitworth J; D. Morgan, Medical Research Council Programme on AIDS, Uganda Virus Research Institute, PO Box 49, Entebbe, Uganda, Tel.: +256 41 320272, Fax: +256 41 321137, E-mail: mrc@starcom.co.ug
Background: Although the majority of HIV-1 infections occur in Sub-Saharan Africa, little is known about the natural history, including survival. However, it is generally believed that HIV disease progresses more rapidly in Africa. Methods: A cohort of HIV-positive and HIV-negative individuals was established in rural
Objective: To assess levels of mortality in HIV-infected and uninfected persons in rural Uganda . Methods: An open cohort of 19,983 adults aged 15-59, in Rakai district was followed at 10 month intervals for four survey rounds. Sociodemographic characteristics and symptomatology/disease conditions were assessed at each
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC430)
van der Loeff MS, Jaffar S, Akum A, Ariyoshi K, Sabally S, Corrah T, Whittle H; MaartenSchim van der Loeff, MRC Laboratories, POBox 273, Banjul, The Gambia, West Africa, Gambia, Tel.: + 220 - 494079, Fax: + 220 - 496513, E-mail: mschim@mrc.gm
Introduction: The natural history of HIV-2 is not well understood, but HIV-2 appears to be associated with a slower progression of disease, and a lower mortality. We compared the survival between HIV-1, HIV-2, and Dually infected patients in a clinic-based, seroprevalent cohort in Fajara, The Gambia . Met
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC431)
Attia A, Huet C, Anglaret X, Dakoury-Dogbo N, N'Dri-Yoman T, Dabis F, Salamon R; A. Attia, Pac-ci, CeDReS, CHU de treichville, BP V3, Abidjan, Cote D'ivoire, Tel.: +225 212 577 53, Fax: +225 212 492 06, E-mail: pacci@aviso.ci
Background: In sub-Saharan Africa where cohort studies are rare, prospective data on HIV-related morbidity and mortality are still lacking. We describe here data on natural history of HIV-1 infection among adults prospectively followed up in Cote d Ivoire. Methods: We studied mortality and occurrence of WHO stage 3 and
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC432)
Cleghorn FR, Jack N, Edwards J, Sill AM, Chah J, O'Brien T, Weinhold K, Greenberg M, Blattner WA, Mahabir B, Bartholomew C; F.R. Cleghorn, Institute of Human Virology, 725 West Lombard St., MBC Rm. 449N, Baltimore, MD 21201, United States, Tel.: (410) 706-1941, Fax: (410) 706-1944, E-mail: sill@umbi.umd.edu
Background:Reliable estimates of time to AIDS in the developing world are critically important if this measure is to be used as a secondary outcome in vaccine efficacy studies being planned to involve both developed and developing countries. Since 1983, Trinidad &
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrC433)
Hira S, Shroff H, Arni S; S. Hira, Aids Research & Control Centre (Arcon), 502 Debonair Apts, Cadell Road, Mahim (W), Mumbai 400 016, India, Tel.: +91 22 444 20 28, Fax: +91 22 444 03 78, E-mail: subhash.hira@lwbbs.net
Background: To study disease progression among ARV-naive cohort of HIV-infected persons in Mumbai. Patients & Methods: Adult patients with confirmed HIV infection and presenting at Sir J. J. Hospital in Mumbai were recruited in the study. 522 patients who were followed prospectively for at least 6 months comprised
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD318)
Rotily M, Weilandt C, Iandolo E, Dos Santos Pardal M, Hariga F, Kall K, Munarriz J, Rousseau S; M. Rotily, ORS PACA - Inserm U379, 23 rue Stanislas Torrents, 13006 Marseille, France, Tel.: +33 491 59 89 01, Fax: +33 491 59 89 18, E-mail: rotily@marseille.inserm.fr
Objectives: To estimate HIV prevalence among inmates and to identify factors related to HIV infection. Methods: This study was carried out in 25 European prisons ( Belgium , France , Germany , Italy , P
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD319)
Saad AC, Bionde EJ, Veiga LP, Santos JL, Carvalho ML, de Souza Gomes J, Leandro EA, Quitete B, Santos ON; A.C. Saad, Rua Barao de Itambi no 60 G2, Rio de Janeiro - Botafogo CEP 2223 1000, Brazil, Tel.: +55 21 399 7338, Fax: +55 21 399 7339, E-mail: anasaad@netfly.com.br
Background: There are a growing number of IDUs in Brazil . From all the cases of AIDS reported, 25% are due to intravenous drug use. A recent study on the prison population of Rio de Janeiro have shown that 4% of the inmates are IDUs (1998). The aim of this research was to study the profile of the IDUs from the Prison
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD320)
Kim A, McFarland W, Kellogg T, Kent C, Kohn R, Snell A, Goldenson J, Bordelon K, Sabin K; A. Kim, San Francisco Department of Public Health, HIV Seroepidemiology Unit, Suite 500, 25 Van Ness Avenue, San Francisco, CA 94102, United States, Tel.: +1 415 554 90 21, Fax: +1 415 431 03 53, E-mail: andrea_kim@dph.sf.ca.us
Background: Evidence points to high levels of HIV and other sexually transmitted diseases (STDs) among inmates entering jails where there is an opportunity to deliver STD screening, treatment, and HIV prevention. Sentinel surveillance surveys in these facilities can monitor HIV/STD incidence and prevalence among hard t
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD321)
Viana M, Gerschuni S, Dos Santos C; M. Viana, Mercedes 1877/703, CP 11200, Montevideo, Uruguay, Tel.: +598 2 408 06 80, Fax: +598 2 408 06 80, E-mail: asepo@adinet.com.uy
Objective: To know the factors contributing for PLWH s HR not be respected within certain prisons in Uruguay . METHODOLOGY ADVOCACY Based on our empirical knowledge through direct contact with PLWH who suffer loss of liberty, on denunciations of violation of HR presented to our institution, and on getting involved in i
Issues: The distribution of sterile syringes, among the injecting drugs users (IDUs), as prevention measure of the HIV and other germs of sanguine transmission have been shown effective outside of the prisons. However, the introduction of this measure in the penitentiary area is very limited. The prison of Bilbao bega
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD323)
Stephenson B, Wohl D, Kiziah N, Rosen D, Ngo B, Merriman N, Kaplan A; B. Stephenson, University of North Carolina, Division of Infectious Diseases, CB# 7030, 547 Burnett-Womack Building, Chapel Hill, N.C. 27599-7030, United States, Tel.: +1 919 966 25 36, Fax: +1 919 966 67 14, E-mail: bls@med.unc.edu
Objectives: To assess the effect of release from prison on viral load (VL) in HIV-infected inmates Methods: Cases were defined as HIV positive inmates on HAART for at least 3 months before they were released and who were re-incarcerated. Controls were HIV positive inmates who remained incarcerated during the case s rel
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD324)
Kumaranayake L, Watts C; L. Kumaranayake, Health Policy Unit, London Sch of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, United Kingdom, Tel.: +44 171 927 2176, Fax: +44 171 637 5391, E-mail: lilani.kumaranayake@lshtm.ac.uk
Background: While there are strong HIV/AIDS interventions across Africa, few are implemented at a national scale. A key priority is the rapid expansion of activities. Despite this, resources to address HIV/AIDs have been relatively limited - external spending on HIV/AIDS in Africa was approximately US$165 million in 19
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD325)
Wu Z, Rou K, Yang G; Z. Wu, Chinese Academy of Preventive Medicine, 27 Nanwei Road, Beijing 100050, China, Tel.: +86 10 6315 2573, Fax: +86 10 6315 2573, E-mail: wuzy@public.bta.net.cn
Issues: The World Bank is now playing a critical role in fighting against the AIDS pandemic in developing countries. This paper summarizes lessons and experiences learned in STD/AIDS intervention from the previous years of the 7th World Bank Health Project. Description: Policy development, capacity building, surveillan
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD326)
Greener R, Jefferis K, Siphambe H; R. Greener, Botswana Institute for Development Policy Analysis, Private Bag BR-29, Gaborone, Botswana, Tel.: + 267 371 750, Fax: + 267 371 748, E-mail: rgreener@bidpa.bw
Background: HIV/AIDS is expected to increase poverty and destitution in Botswana . The objective was to quantify the impact of HIV/AIDS on indicators of poverty and income inequality, and to explore the policy implications. Methods: Current HIV prevalence rates by age, sex and location were randomly imposed upon house
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD327)
Gomez M, Carson T, Carson T; M. Gomez, 200 Independence Ave, SE, Room 736E, Washington, DC, 20210, United States, Tel.: +1 202 690 11 94, Fax: +1 202 690 75 60, E-mail: mgomez@osophs.dhhs.gov
Issues: The rates of new HIV infections and HIV-related mortality among minorities in the U.S. continue to increase at an alarming pace. In 1998, racial and ethnic minorities accounted for 52% of the AIDS cases diagnosed for gay men - 21% higher than in 1989. Often leaders within minority communities carry negative pe
Issue: Networking is an essential part of a non-governmental AIDS organisation s activities. Networking with developed countries shows us their greater experience and skills, thus giving stimulus in our work and helping financially. But lots of good initiatives arise from networking with the like, too. Description: La
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD329)
Alakbarov R, Ibrahimova J, Melikov K; R. Alakbarov, United Nations Population Fund, 3, UN 50th Anniversary street, 370001, Baku, Azerbaijan, Azerbaijan, Tel.: +(99412) 922470, Fax: +(99412) 922379, E-mail: ramiz.alekperov@un.azeri.com
Issues: A first comprehensive review of the HIV/AIDS response in Azerbaijan has been conducted and became a basis for launching the response actions. Gathered planning and implementation experience is discussed both from the prioritization and impact point of view by sectors. Country specific lessons learned from intro
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD330)
Bouhnik AB, Moatti JP, Vlahov D, Gallais H, Dellamonica P, Obadia and the MANIF 2000 Stud Y; A.B. Bouhnik, Regional Center for Disease Control (ORSPACA), 23, rue Stanislas Torrens, 13006 Marseille, France, Tel.: +33 4 91 59 89 19, Fax: +33 4 91 59 89 18, E-mail: bouhnik@marseille.inserm.fr
Background: Highly Active Antiretroviral Therapies (HAART) have given new hope for people living with HIV, in terms of quality of life and life expectancy. Concerns have, however, been raised that diffusion of HAART may increase risky behaviors among HIV-infected persons. This study examined the impact of HAART on sexu
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD331)
McDonald K, Bartos M, Grierson J, de Visser R; K. McDonald, 215 Franklin Street, Melbourne, Victoria 3000, Australia, Tel.: +613 928-551-08, Fax: +613 928-552-20, E-mail: k.mcdonald@latrobe.edu.au
Background: There has been considerable public discussion on the impact of advances in antiretroviral therapy (ARV) in sexual practice, but little of this has focussed on arguably the most important affected population, namely people living with HIV/AIDS (PLWHA). Method: The `HIV Futures Survey in
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD332)
Spire B, Duran S, Raffi F, Sobel A, Souala F, Journot V, Cailleton V, Leport C, Moatti J-P; B. Spire, INSERM U379, 23 Rue Stanislas Torrents, 13006 Marseille, France, Tel.: +33 4 915 989 06, Fax: +33 4 915 989 18, E-mail: spire@marseille.inserm.fr
Background: With the advent of highly active antitretroviral therapy (HAART), the issue of patient s adherence to treatment has become crucial in the clinical and public health management of HIV infection. Therefore, our objective was to assess short-term self-reported symptoms after HAART initiation in the multi-cente
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD333)
Starace F, De Gaetano A, Chirianni A, Abrescia N, Angarano G, Bonadies G, Guaraldi G, Lazzarini L, Lo Caputo S, Maserati R, Tramarin A, D'Onofrio G; F. Starace, Consultation Psychiatry Service, Via G. Quagliariello, 54, 80131 Naples, Italy, Tel.: +39 081 590 8202, Fax: +39 081 590 8430, E-mail: starace@libero.it
Background: Patient s adherence to treatment is a crucial issue for the long term success of antiretroviral (ARV) therapies. Psychosocial factors play an important role as determinants of non-adherence (NA). Methods: A cross-sectional multicentre study has been carried out in 8 Italian clinical centres to assess psycho
Background: This study examines the psychosocial factors that contribute to nonadherence among a sample of HIV-positive African Americans from Detroit, Michigan, USA. Method: Information on living circumstances, health status, and experiences in living with HIV for 60 African American HIV-positive adults (29 women and
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD335)
Remien RH, Wagner G; R.H. Remien, Unit #15, 1051 Riverside Dr., NY, NY 10032, United States, Tel.: +1 212 543 5375, Fax: +1 212 543 6003, E-mail: rfr1@columbia.edu
Background: Medication adherence is an integral factor in the success of HAART. Poor adherence can lead to the development of drug resistant virus that can be transmitted to uninfected partners. Little is known about the relationship between adherence to antretroviral therapy and adherence to safer sex practices. Metho
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD373)
Gross J, Braswell A; J. Gross, AID Atlanta, Suite 100, 1438 West Peachtree Street NW, Atlanta, GA 30309, United States, Tel.: +1 404 870 77 65, Fax: +1 404 885 67 99, E-mail: grossj@aidatlanta.org
Issues: Peer education has been a successful method of HIV/AIDS prevention in the United States . ASK US (Adolescents Seeking Knowledge to Understand Safer Sex and STDs) is an AID Atlanta peer education group located in Atlanta, Georgia that works with teens to provide accurate, age-appropriate HIV and sexually transmi
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD374)
Chang TK; Terence T. K. Chang, Teen AIDS, 116 Aberdeen Main Road, Aberdeen, Hong Kong, China, Tel.: +85 2 2870 1222, Fax: +85 2 2870 3623, E-mail: tchang@TeenAIDShk.org
Issues: More than 50 social group and high-risk group to be infected by AIDS. Teen AIDS Interactive Model of AIDS/Sex Education on Youth employs art and games to advocate AIDS prevention and discrimination. Art can touch the heart of youth and let them feel the need to concern and support. Art is a powerful tool in AID
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD375)
Seguy N, Nawej K; N. Seguy, Medecins Sans Frontieres Belgique, 1 avenue OUA, BP 1599 Kinshasa, Congo, The Democratic Republic, Tel.: +243 462 92, Fax: +243 883 360, E-mail: msfb.kin@raga.net
Backgrounds: a study made in 1996 in secondary schools of DRC has shown that 43% of pupils aged 12 to 16 had already sexual intercourse. In 1999, 370.000 leaflets on HIV/STD were conceived and distributed to adolescent studying in the first year of secondary schools, in 7 provinces of the country. Some schools have bee
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD376)
Gaskins S, Beard S; S. Gaskins, The University of Alabama, Capstone College of Nursing, Box 870358, Tuscaloosa,Alabama 35487, United States, Tel.: +1 205 348 1027, Fax: +1 205 348 5559, E-mail: sgaskins@nursing.ua.edu
Issue: School based HIV/AIDS prevention programs that prepare students with knowledge, attitudes, and skills needed to avoid infection with HIV are encouraged and even mandated in some areas. Most programs target students in middle, junior, or high school. Early elementary HIV/AIDS education has been unfocused and gene
Issues: The region of Banfora, near the border of Burkina and Cote d Ivoire , provides workers for the agro-industrial complexes and is especially affected by the AIDS epidemic. New cases are mostly among the young. Students constitute a vulnerable group. Objectives of the intervention: i) improve understanding of STDs
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD378)
Wolf RC, Bond KC, Tawfik LA; R. C. Wolf, Johns Hopkins School of Public Health, Faculty of Social and Behavioral Sciences, 624 North Broadway, 7th floor, Baltimore, Maryland 21205, United States, Tel.: +410 539-6010, Fax: +410 955-7241, E-mail: cwolf@jhsph.edu
Background: The data presented in this paper point out the importance of social context and influence on youth, how social networks are related to the adoption of safe behaviors and perception of risk, how program messages move through communities, and what services and messages are being delivered during peer educatio
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD379)
Kongsin S, Sirinirund P, Jiamton S, Boonthum A, Watts C; S. Kongsin, London School of Hygiene and Tropical Med., Health Policy Unit, Department of Public Health and Policy, London WC1E 7HT, United Kingdom, E-mail: sukhontha@hotmail.com
Background: To conduct a comparative analysis of households affected and not affected by chronic HIV morbidity, and between affected households within communities with different levels of available services in order to further understand household s coping strategies in the presence of chronic HIV morbidity in their fa
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD380)
Thea D, Simon J, Rosen S, Vincent J, Singh G; D. Thea, Health Office, 14 Story Street, Cambridge, MA 02138, United States, Tel.: +617 495 9791, Fax: +617 495 9706, E-mail: dthea@earthlink.net
Issues: The impact on companies of HIV in the workforce in developing nations is not well understood. Few attempts have been made to quantify the effects of HIV/AIDS morbidity and mortality on the profitability of private sector firms; most were done early in the epidemic and were based largely on interview data. Descr
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD381)
Greener R, Jefferis K, Siphambe H; R. Greener, Botswana Institute for Development Policy Analysis, Private Bag BR-29, Gaborone, Botswana, Tel.: +267 371 750, Fax: +267 371 748, E-mail: rgreener@bidpa.bw
Background: HIV/AIDS poses a threat to continued economic growth in Botswana . The objective was to estimate the impact of HIV/AIDS on macroeconomic indicators such as the gross domestic product (GDP) and unemployment. Methods: A two sector, three factor equilibrium model for the Botswana economy was constructed. The
Objective: To compare the distribution of HIV prevalence and AIDS defining symptoms between adult heads and non-heads of households in rural Rakai district. Design and Setting: Community-based, randomized, controlled, single blinded trial, conducted in 56 communities in Rakai district, southwestern Ug
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD383)
Lundberg M; M. Lundberg, The World Bank, 1818 H Street, NW, Washington, DC, 20433, United States, Tel.: +202-473-3217, Fax: +202-522-1157, E-mail: mlundberg@worldbank.org
Background: The provision of assistance to AIDS survivors has been the focus of a great deal of operational work by international agencies, governments, and non-governmental organizations (NGOs). Most households receive transfers from the state and NGOs as well as from other households. How effective are these transfer
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD384)
Diaz A, DeFino M; A. Diaz, Montefiore Medical Center, 111 East 210th Street, Gold Zone, ID Clinic, Bronx, New York 10467, United States, Tel.: +718-920-85-04, Fax: +718-405-06-10, E-mail: diazaaron@hotmail.com
Issues: Research has proven the adverse results of non-adherence to antiretroviral therapy (ART). The purpose of this abstract is to emphasize the importance of the MAC to a multidisciplinary team. Description: With the development of a Medication Adherence Program, a interdisciplinary team reinforces patient education
Issue: to improve the adherence to treatments, especially with antiretrovirals, in Brazil . Description: the workshop consists in sharing experiences among PWHIV/AIDS and also providing basic information on ARVs and hints to overcome difficulties in adherence. The workshop lasts 6 hs. We begin providing a historical b
Issues: Traditionally HIV infected people accessing hospitals received doctor centric care which was limited by time resources and interrested staff. Implementation of an integrated health careworker approach to care has resulted in greater amounts of information being available for patients. This has resulted in great
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD387)
Kiyimba W, Pool Konde C, Byamukama A, Mulindwa M, Mugisha E, Kityo C, Mugyenyi P; W. Kiyimba, Joint Clinical Research Centre, P. O. Box 10005, Kampala, Uganda, Tel.: +256-41-270622, Fax: +256-41-342632, E-mail: jcrc@starcom.co.ug
Background: Being diagnosed HIV positive is detrimental to the individual in our set up of limited facilities. It demands a lot of support from health care giver to help the new client cope with the situation. Objective: To help the people cope and comply with long term treatment of Anti-retroviral, the management of o
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD388)
Adams IK, Rezende Vargas M, Nogueira Duarte R, Rodrigues de Souza R; I. K. Adams, Clinica Nossa Senhora Conceicao, Rua Saldanha da Gama 256/302, Belo Horizonte, M.G. 3111-210, Brazil, Tel.: +55 31 444 34 31, Fax: +55 31 442 91 82, E-mail: irenedra@gcsnet.com.br
Background: Repeated, prolonged, hospitalizations for manifestations of HIV infection were reduced in a resource poor setting by involvement of family and community in resolving social situations (food, housing, clean water, drains, family relations and chemical dependence) that were contributing to poor outcomes. A su
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD389)
Haikalis S; S. Haikalis, San Francisco AIDS Foundation, PO Box 426182, San Francisco, CA 94142-6182, United States, Tel.: +1 415 487 80 26, Fax: +1 415 487 80 09, E-mail: shaikali@sfaf.org
Issues: San Francisco offers comprehensive health & social services to its 15,000 HIV+/AIDS residents. The healthcare system includes primary medical, OPD, hospital, hospice & medications. A public health system provides free care for HIV+ residents without health insurance. The San Francisco AIDS Foundation (S
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD434)
Haoses L, Van der Veen F; L. Haoses, University of Namibia, Private Bag 13301, Windhoek, Namibia, Tel.: +264-61-206 32 00, Fax: +264-61-206 39 22, E-mail: nacp@iafrica.com.na
Objectives: To raise awareness on STD and HIV/AIDS, and personal risk factors among students, teaching staff and management of the University of Namibia (UNAM). Methods: A one page questionnaire was submitted to all students of during the registration procedures together with educational materials and condoms. Results
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD435)
Xaba N, Kunene P, Harrison A; N. Xaba, Box 198, Mtubatuba 3935, South Africa, Tel.: +27 35 550 0158, Fax: +27 35 550 1674, E-mail: harrisoa@mrc.ac.za
Background: The gap between awareness and behaviour in South Africa is well known, yet few studies have examined understanding of prevention messages. We asked high school youth for their interpretation of the HIV/AIDS epidemic s most enduring concept, safe sex , to better understand barriers to prevention. Methods: I
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD436)
Bjegovic V, Cucic V, Vukovic D; V. Bjegovic, Belgrade University, School of Medicine, Institute of Social Medicine, Dr Subotica 15, 11000 Belgrade, Yugoslavia, Tel.: +381 11 643 830, Fax: +381 11 659 533, E-mail: bjegov@eunet.yu
Background: Numerous studies illustrate that besides HIV/AIDS related knowledge, prompt development of safe sexual practice is substantial part of AIDS prevention among school children. The objective of this study is to examine actual sexual behavior of school children as initiative step of AIDS preventive intervention
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD437)
Hausner D;;; D. Hausner, 810 Houston Avenue, Apartment 1, Takoma Park, Maryland 20912, United States, Tel.: +1 301 585 83 01, Fax: +1 301 585 25 71, E-mail: HausnerDavid@cs.com
* Background: The objective of this study was to understand the sexual behavior and knowledge of college students in an urban center in south India in the context of HIV risk, and to use the results to develop program recommendations for HIV prevention. Methods: In-depth interviews were conducted with 35 male students
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD438)
Cunningham I, Beltrin J, Mattei H, Perez Jimenez E; I. Cunningham, 773 Ceres Dos Pinos, San Juan, Puerto Rico 00923, Puerto Rico, Tel.: +1 787 764 0000/2925, Fax: +1 787 772 1431, E-mail: icunning@upracd.upr.clu.edu
Background: Based on the results of 3 large-scale surveys at the largest campus of the University of Puerto Rico , a five-year study was developed about the construction of sexuality and gender roles and how these relate to sexual negotiation and safer sex practices. Methods: A convenience sample of 221 participants (
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD439)
Mzaidume Y, Asiedu K, Ndhlovu L, Campbell C; Y. Mzaidume, Mothusimpilo Project, C/O Population Council, Unit 2 The Oaks, 368 Oak Avenue, Randburg 2194, PO Box 2823, Randburg 2125, South Africa, Tel.: +27 11 781 3922, Fax: +27 11 781 3960, E-mail: lndhlovu@pcjoburg.org.za
Issues: The gold mining industry in South Africa , employing a large migrant workforce housed in single sex hostels, is considered to contribute disproportionally to the spread of STDs and HIV infection in Southern Africa. While miners can relatively easily be reached with preventive messages and condom distribution pr
Issues: In recent years sex work migration in and from Central and Eastern Europe has been increasingly criminalised. However this development neglects that sex work migration often offers migrating sex workers access to improved HIV/STD information and increasingly sophisticated services intended to support safer sex
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD441)
Wallace J, Weiner A, Whitten W, Browning L, Canty R; J. Wallace, From Our Street With Dignity (FROSTD), 369 Eighth Avenue, NYC, NY 10001, United States Minor Outlaying, Tel.: +1 212 924 3733, Fax: +1 212 924 8086, E-mail: weinerap@idt.net
Background: Since April 1989, a mobile outreach van operated by the not-for-profit organization From Our Streets With Dignity (FROST D) has been providing services to streetwalking prostitutes. HIV counseling and testing as well as distribution of condoms and bleach kits for needle cleaning and HIV prevention informati
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD442)
Zhao P, Yu H; P. Zhao, 2140 Xie Tu Road, Shanghai 200032, China, Tel.: 86-21-6404-9215, Fax: 86-21-5461-3218, E-mail: zhaopf@sippr.stc.sh.cn
Background: Shanghai currently has the highest reported STI incidence in China , to a level of 314.2/100,000 in 1998. Health services in Shanghai had significantly improved over the past decade. However, many people with STI symptoms still delay seeking effective care. This project aimed to identify barriers to the use
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD443)
Madrid Romero E; E. Madrid Romero, Brigada Callajera de Apoyo a la Mujer, Corregidora 115 D204, Mexico, DF 15100, Mexico, Tel.: +525 542 7835, Fax: +525 542 7835, E-mail: guerita@laneta.apc.org
Background: In 1995 the distribution of free condoms by international agencies came to an end, provoking a black market of condoms past their expiration date. The price of commercial condoms are prohibitively expensive for the target population of low income sex workers. Further, cultural, educational, psychological ba
Background: In many previous studies the Health Belief Model (HBM) has been used to conceptualize behavioral factors associated with HIV/AIDS transmission. The objective of this study was to examine the association of three HBM constructs Perceived susceptibility, Perceived Barriers and Perceived Benefits, and other fa
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD445)
Levy J, Valle M; J. Levy, University of Illinois, Chicago, School of Public Health, Epi/BIO, 2121 West Taylor, M/C 922, Chicago, IL 60612-7260, United States, Tel.: +1 312 996 7825, Fax: +1 312 996 0064, E-mail: judlevy@uic.edu
Background: Disclosure of positive HIV status can result in negative consequences including stigmatization, disruption of interpersonal relationships, and job or housing discrimination. Yet informing others is important in notifying partners of shared exposure, establishing social service and treatment eligibility, an
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD446)
Poindexter C; C. Poindexter, Boston University, School of Social Work, 264 Bay State Road, Boston, MA 02215, United States, Tel.: +1 617 353 77 21, Fax: +1 617 353 56 12, E-mail: ccp@bu.edu
Issue: Grandparents raising grandchildren is not a new phenomenon in the U.S.; however, it has emerged as an especially pressing problem in the HIV epidemic. Most surrogate parents for children who are orphaned by HIV are relatives over age 50. They are caring for bereaved and/or chronically ill children at a time when
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD447)
Garda L, Rao VN, Khasnis S, Raut PB; L. Garda, Kem Hospital Research Centre, Sardar Moodliar Road, Rasta Peth, Pune - 411 011, Maharashtra, India, Tel.: +91 20 625 600 EXT. 336, Fax: +91 212 625 603, E-mail: kemhrc@vsnl.com
The research paper presents the demographic profile and transmission patterns of HIV/AIDS and stigmatization and discrimination of vulnerable rural women in Maharashtra ( India ). This is based on an ongoing study carried out for formulating effective and culturally suitable strategies to combat the epidemic of HIV/AI
Issues: HIV vaccine trial participants may be subject to social harms such as stigmatization (by identification of high-risk group membership); misclassification of HIV infection status (due to vaccine-induced antibody) resulting in loss of employment, insurance, or travel restrictions; or increased risk behavior due
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD449)
Dey B, Jana S, Manna R, Biswas K, Mondal U, Ghosh M, Bibi M, Pal S, Adhikari K; B. Dey, 8/2 Bhawani Dutta Lane, Calcutta 700 073, India, Tel.: +91 33 241 5253, Fax: +91 33 241 6283, E-mail: ship@cal.vsnl.net.in
Issues: Trafficking has become a critical issue in the agenda of working with SWs and HIV. However, debate on trafficking is dominated by perspectives of non SWs, which take a moral high ground on sex and sex work without giving any voice to SWs. Sonagachi project did a research to explore what the SWs think about traf
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrD450)
Mohale B;;; B. Mohale, Health Systems Development Unit, POBox 2, Acornhoek 1360, South Africa, Tel.: +27-13-797-0076, Fax: +27-13-797-0082, E-mail: pronyk@soft.co.za
Issues: In spite of current efforts to raise awareness regarding HIV/AIDS, in many parts of Africa, fear, stigma, and denial continue to impede HIV education and prevention efforts. This is particularly true in rural areas where there are few resources for education and outreach, and where myths and misconceptions cont
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrE279)
Cortez GV;;; G. V. Cortez, National AIDS/STD Program, Department of Health, San Lazaro Compound, St Cruz, Manila, Philippines, Tel.: +63 2 743 83 01, Fax: +63 2 743 05 12, E-mail: gladysvc@yahoo.com
Issues: The gravity of the AIDS threat demands strong state action. The enactment of RA 8504, the Philippine AIDS Prevention and Control Act of 1998, does not however guarantee that mandatory testing doesn t take place, that confidentiality is not violated, and that discrimination won t happen. The challenge of popular
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrE280)
Levin MB;;; M.B. Levin, Georgetown Medical School, 1421 Massachusetts Ave., NW, #503, Washington, DC 20005, United States, Tel.: +1 202 332 32 99, E-mail: levimb@hotmail.com
Issues: The United Nation s Programme on AIDS anticipates that by the year 2005, there will be more adults living with HIV in India than the entire continent of Africa. Failure to control this epidemic will undermine India s previous successes in reducing infant mortality and increasing adult life expectancy, particul
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrE281)
Philpott A; AnnePhilpott, 41 Holland Rd, London NW10 5AH, United Kingdom, E-mail: anniephilpott@hotmail. com
Issues: The interface between research and policy for one case studyx was analysised in order to determine perceptions of the relationship between research and policy. Specifically to what extent the study itself determined global HIV policy shift, in relation to the increasing emphasis of sexually transmitted disease
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrE336)
Stover J, Rehnstrom J, Schwartlander B; J. Stover, The Futures Group International, 80 Glastonbury Blvd, Glastonbury, CT 06033, United States, Tel.: +1 860 633 35 01 x 202, Fax: +1 860 657 39 18, E-mail: j.stover@tfgi.com
Background: There are many measures of specific inputs to AIDS programs (e.g., number of condoms distributed, STD cases treated) and outcomes (e.g., HIV prevalence, number of reported AIDS cases). However, there are no measures of the overall level of effort made in response to the epidemic. Such a measure would be use
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrE337)
Jeannin A, Schmid M, Huynh Do P, Spencer B, Dubois-Arber F; A. Jeannin, Institut Universitaire de Medecine sociale, Rue du Bugnon 17, CH-1005 Lausanne, Switzerland, Tel.: +412 131 472 96, Fax: +412 131 472 44, E-mail: andre.jeannin@inst.hospvd.ch
Issues: Effective planning and implementation of national HIV/AIDS strategies calls for the development of methodological evaluation tools which may be applied nationwide and comprehensively regarding all aspects of prevention and treatment. Prior to the launching of a new phase of the HIV/AIDS federal strategy in
Int Conf AIDS 2000 Jul 9-14; 13:(abstract no. TuOrE338)
Floyd L;;; L. Floyd, Gauteng AIDS Unit, Gauteng Provincial Government, Private Bag X085, Marshalltown 2107, South Africa, Tel.: +27 11 355 3394, Fax: +2
