AEGiS-14IAC: Dyslipidaemia in HIV infection with or without Tuberculosis.

14th International AIDS Conference


Barcelona, Spain - July 7-12, 2002

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Dyslipidaemia in HIV infection with or without Tuberculosis.

Int Conf AIDS 2002 Jul 7-12; 14:(abstract no. B10239)

Das PK, Das PC
Ross Clinical Laboratory, Kolkata, India

BACKGROUND: Though minor controversy exists lipid alterations do occur in cases of HIV infection. Of various types of infection tuberculosis is a very common accompaniment in such cases. Thus we were interested to find out the lipid alteration in cases of HIV infection with or without tuberculosis.

METHOD: A total of 60 consecutive cases of HIV infection formed the basis of this study. Of these, 37 were males and 23 were females and their ages ranged between 18 years and 40 years. Out of these 60 cases, 30 cases were having tuberculosis in some form or other. Serum lipids mainly cholesterol, triglycerides and HDL cholesterol were estimated in all by standard methods. Thirty age and sex matched individuals served the purpose of controls. RESULT: The result that mean cholesterol level in HIV infection was 153.03±21.06 mg/dl (control 175.47±20.98 mg/dl), triglyceride 125.83±27.84mg/dl (control 121.5±15.31mg/dl), HDL 35.33±2.23mg/dl (control 44.67± 6.22mg/dl). These changes were statistically significant (p< 0.001) in all, except with triglyceride. In cases of HIV infection without tuberculosis the mean levels of cholesterol triglyceride and HDL were 154.7±24.55mg/dl, 128.27±32.86mg/dl and 35.30±2.10mg/dl respectively; in the tuberculosis group these levels were 156.7±17.15mg/dl, 123.4±22.01mg/dl and 35.37±2.39mg/dl respectively. These lipid changes in non-tuberculosis group though present numerically yet they were not statistically significant. No interrelation was however found between these lipid parameters.

CONCLUSION: Cholesterol and HDL levels were reduced in HIV infection in comparison to control group, which was statistically significant. However though numerical changes in lipid parameters were present any non-tuberculosis group and tuberculosis group these changes were not statistically significant.

Keywords: AEGIS, Tuberculosis, HIV Infections, Hyperlipidemia, Lipoproteins, HDL Cholesterol, Triglycerides, Cholesterol, Lipids, Case-Control Studies, Human, Female, MaleKWDaegis,tuberculosis,hivinfections,hyperlipidemia,lipoproteins,hdlcholesterol,triglycerides,cholesterol,lipids,case-controlstudies,human,female,male

020707
B10239

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