AEGiS-14IAC: Oral lesions associated to human immunodeficiency virus infection or acquired immunodeficiency syndrome in individuals without antiretroviral treatment in Bogota (Colombia).

14th International AIDS Conference

Barcelona, Spain - July 7-12, 2002

Oral lesions associated to human immunodeficiency virus infection or acquired immunodeficiency syndrome in individuals without antiretroviral treatment in Bogota (Colombia).

Int Conf AIDS 2002 Jul 7-12; 14:(abstract no. B10253)

Montoya JH
Universidad Nacional de Colombia, Bogota, Colombia

BACKGROUND: Oral disease may represent the first sign of the disease in HIV-infected individuals and have been shown to be highly predictive marker of severe immunosuppression and disease progression. A review of the literature shows that there is hardly any published data on oral manifestations of HIV infection or AIDS from the Latin America region.

METHODS: It was carried out a descriptive study with 314 patients living with the HIV of Bogota (Colombia).They were examined registering lesion type (as classified by the EC-Clearinghouse on oral problems related to HIV infection and the WHO collaborating centre), presentation place, gender and age.

RESULTS: Of the examined patients,90,8% were men and 9,2% were women. The median age was 31 years.223 (71%) of the patients revealed oral lesions. Common lesion was oral candidosis in (65,8%) -pseudomembranous in 30%, erythematous in 21%, angular queilitis in 12% and hiperplasic in 2,8%-. Oral hairy leucoplaquia was seen in 21,3%, gingivitis and periodontitis in 17,1%, Kaposi sarcoma in 8,9% and recurrent aphtous ulcers in 8,2%. The affected places were the hard and soft palate in 34,4%, the tongue in 32,2%, the mucous yugal in 15,3% and the marginal gum in 11,5%.

CONCLUSIONS: The pattern of occurrence of various lesions reported appears to show variation from those reports from other parts of the world. The discoveries allow to contrast the information about the frequencies of presentation of the main oral lesions in populations of developed countries and underdeveloped with and without access to antiretroviral treatment. They define the especific morbidity profile of the patients' of Bogota (Colombia) for the studied period, that which can be explained by the epidemic pattern in that Colombia was for that time and for the time of realization of the study. Further epidemiological studies are necessary to understanding the nature of oral lesions in Latin American countries.

Keywords: AEGIS, Acquired Immunodeficiency Syndrome, HIV Infections, Mouth Diseases, Candidiasis, Oral, Sarcoma, Kaposi, HIV Seropositivity, Disease Progression, Antiretroviral Therapy, Highly Active, Gingivitis, Epidemiologic Studies, Colombia, Latin America, Human, Female, Male, therapy, drug therapy

020707
B10253