AEGiS-14IAC: Comparison between years 1999 and 2000 of a prevalence study of antiretroviral therapy in patients assisted at Buenos Aires hospitals. Buenos Aires. Argentina.

14th International AIDS Conference

Barcelona, Spain - July 7-12, 2002

Comparison between years 1999 and 2000 of a prevalence study of antiretroviral therapy in patients assisted at Buenos Aires hospitals. Buenos Aires. Argentina.

Int Conf AIDS 2002 Jul 7-12; 14:(abstract no. C10673)

Beltran M, Dinerstein E, Raffo L, Cordeiro OR, Pallone E, Warley E, Couso M, Loza S, Forcinitti S, Leroux C, Obieta E, Canataro P, Vizgarra M, Gil R, Juodis A, Cohen E, de Luca M, Layna A, Blasco M, Garda P, Basombrio A
Hospital San Isidro, Buenos Aires, Argentina

BACKGROUND: in 1999 we did the first prevalence study of antiretroviral therapy (ART) in HIV / AIDS patients who assisted to 19 hospitals in Buenos Aires, Argentina. We decided to compare obtained data with a new study performed during three months of year 2000.

METHODS: data were obtained from clinical charts and studied with Epi-Info vs. 5.0. 2x2 tables were done to perform x2 tests.

RESULTS: in 1999 were evaluated 1601 patients from 19 hospitals. In 2000 we studied 1418 patients from 13 hospitals. We found non significant differences for the following variables: age (32.1 years in 1999 and 33.6 years in 2000), masculine gender (58.7% and 57.8%), primary school (37% and 39.3%), sexual HIV risk category (54.8% and 56.7%), IVDU's (40.7% and 39.9%), receiving ART (73.4% and 73.2%), receiving drugs from the National Control Programme (82.8% and 85.3%), receiving their first ART (46.8% and 47.3%). 139 patients in 1999 and 110 in 2000 never accepted ART. There was a significant fall in the number of patients treated with a combination of two drugs (p<0.0001) and more patients were treated with 3 drugs without a protease inhibitor (P.I.) (p<0.0001). More patients had PVL control determinations (56% in 1999 and 64.5% in 2000, p=0.0001). Similar number of patients had <500 ARN copies/ml at their last PVL (54.1% in 1999 and 57.8% in 2000, p=0.08). In year 2000 where introduced more sensitive PVL determinations. 38% of patients of 2000 had <50 ARN copies/ml. In 1999 72.6% of patients had >200 CD4+ cells/ml. In 2000 this percentage was 70.5%. p=0.4. Cocnclusions: 1-in year 2000 we found more patients treated with a combination of three drugs without P.I. 2-more patients had control PVL. 3-similar number of patients had PVL values of <500 ARN copies/ml in 1999 and 2000. 4- 38% of patients of year 2000 had <50 ARN copies/ml. 5-similar number of patients had <200 CD4+ cells/ml.

Keywords: AEGIS, HIV Infections, Antiretroviral Therapy, Highly Active, Acquired Immunodeficiency Syndrome, CD4-Positive T-Lymphocytes, Argentina, Human, therapy, drug therapy

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