AEGiS-14IAC: Characteristics of newly HIV diagnosed adults in Spain and patterns of Antiretrovirals use: The PISCIS cohort study.

14th International AIDS Conference


Barcelona, Spain - July 7-12, 2002

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Characteristics of newly HIV diagnosed adults in Spain and patterns of Antiretrovirals use: The PISCIS cohort study.

Int Conf AIDS 2002 Jul 7-12; 14:(abstract no. C10682)

Pozuelo A, Gatell JM, Casabona J, Podzamczer D, Villalonga C, Miro JM, Ferrer E, Riera S, Force L, Segura F, Vilaro JM, Garcia I, Masabeu A, Tural C, Altes J, Dorca E
CEESCAT, Badalona, Spain

BACKGROUND: In 1998 a multicenter prospective study (PISCIS) was implemented to recruit all HIV patients attended from that time in 10 hospitals from Catalonia and 1 from Balearic Islands. This abstract describes the characteristics epidemiological and biological of newly diagnosed HIV cases and the evolution of the Antiretroviral prescription pattern.

METHODS: The PISCIS Minimum Common Data set (MCD) includes epidemiological, clinical and biological data. Follow up is performed according to the physicians criteria, but the MCD is systematically updated every 4 months. Till September 2001, 2340 patients have been enrolled. For the purpose of describing the newly infected patients, only those actually diagnosed of HIV after January 1998 were included 1107 (47%).

RESULTS: Out of 1107 newly infected: 831(75%) men 276(25%) women, being women younger (ma: 32) than men (ma:36). Transmission categories: 36 % IDU, 28 % MSM and 24 % Hetero for men; 22% IDU and 63% Hetero for women. For the 798 (72%) patients in which this data was available at diagnosis, the median of CD4 was 156 c/mm3 (P25: 47 - P75: 395) and the median of viral load (VL) was 103.000 c/ml; in 32 (4,4%) of them VL was undetectable (<200 copies/ml). For all enrolled the ARV pattern at the end of the year was:[table: see text]

CONCLUSIONS: According to our data heterosexual transmission is becoming the first route of HIV adcquisition, particularly among women. There is a high proportion of probable late diagnosis (CD4 <200 c/mm3 and a VL> 100.000 c/ml). 80% of the patients are currently treated and a shift from IP to NNRTI has been identified.

Keywords: AEGIS, HIV Infections, Cohort Studies, Viral Load, HIV Seropositivity, CD4 Lymphocyte Count, Heterosexuality, Antigens, CD4, Spain, Adult, Human, Female, Male, Diagnosis, immunologyKWDaegis,hivinfections,cohortstudies,viralload,hivseropositivity,cd4lymphocytecount,heterosexuality,antigens,cd4,spain,adult,human,female,male,diagnosis,immunology

020707
C10682

Copyright © 2002 - International AIDS Society (IAS). Reproduction of this abstract (other than one copy for personal reference) must be cleared through the IAS.