AEGiS-14IAC: Maternal and perinatal outcome in HIV seropositive women.

14th International AIDS Conference


Barcelona, Spain - July 7-12, 2002

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Maternal and perinatal outcome in HIV seropositive women.

Int Conf AIDS 2002 Jul 7-12; 14:(abstract no. C10715)

Ramasamyshoba R
Institution, Chennai, India

BACKGROUND: to assess and evaluate the influence of hiv - 1 infection on the maternal and perinatal outcome of pregnant hiv sero positive women.

METHODS: a case-control study of 1:3 ratio with socio-demographic, behavioural risk factors of women and partners, clinical characteristics and pregnancy outcome were assessed using x2 test, p value & oddsratio, conducted at the antenatal clinic of the institute of obstetrics & gynaecology, chennai (naco - mtct study center) from jan 2000 to sep 2001.

RESULTS: antenatal patients, vct offered, prevalence rate 0.5%. Pregnant women - iliterates, primary education, had a significantly high hiv infectivity rate than those who had higher education (x2=19.9, p=0.00005). HIV infection was 6.1 times (odds) in housewives than employed (x2 =9.18, p=0.0024), 48% of positive mothers were from rural area and 50% were referred cases. Risk behaviour status was present in 24% of cases against 12% in controls. 22% of cases had an additional std to only 10% in controls. Partners with primary education (x2=31.0, p<0.000001), unskilled labours (odds -2.5 times), drivers (odds - 5.8 times), with high risk behaviour and std (odds - 14.2 times, 66% cases vs 5% controls) had a significant association with hiv infection. Complicated antenatal period with preterm labour, prom (8% vs 1%), oligohydramnias with iugr (18% vs 8%) and intrauterine death (16% vs 0%) were statistically significant. postpartum morbidity like anaemia, (22% vs 14%), infectious morbidity (10% vs 3%), high neonatal deaths were observed.

CONCLUSION: poor literacy, high risk behaviour, std in both partners are important risk parameters where primary preventive interventions can be adopted. maternal and perinatal morbidity is higher in seropositive women, interventions need to be designed to reduce the same.

Keywords: AEGIS, HIV Seropositivity, HIV Infections, Parturition, Risk Factors, Mothers, Prevalence, Case-Control Studies, Pregnancy Outcome, India, Human, Adult, Female, PregnancyKWDaegis,hivseropositivity,hivinfections,parturition,riskfactors,mothers,prevalence,case-controlstudies,pregnancyoutcome,india,human,adult,female,pregnancy

020707
C10715

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