AEGiS-14IAC: Clinical pattern of AIDS and gender-related differences in two different periods (1989 and 1999), in Bahia, Brazil.

14th International AIDS Conference

Barcelona, Spain - July 7-12, 2002

Clinical pattern of AIDS and gender-related differences in two different periods (1989 and 1999), in Bahia, Brazil.

Int Conf AIDS 2002 Jul 7-12; 14:(abstract no. C10738)

Brites C, Sampaio M, Melo J, Jesus V, Badaro R
Secretary of Health of Bahia State, Salvador, Brazil

OBJECTIVE: to compare the pattern of AIDS before and after antiretroviral therapy become available for all patients, in Bahia, Brazil. Methods- We reviewed the databank of Secretary of Health of Bahia (SESAB), in Northeast Brazil. The reported AIDS cases (years of 1989 and 1999) were compared, in order to assess differences in clinical presentation and epidemiological characteristics of AIDS at the time of diagnosis.

RESULTS: Mean age was similar, regardless gender. The male-to-female ratio decrease from1:8 to 1:2 within the period. We also noted a decrease in the rates of men with university degree (75% vs. 50%), and for women (25% vs. 20%). Contamination by IV drugs use diminished from 27% to 13% for men and 13% to 8% for women. The number of women reporting sexual relationship with IVDU partners (0 vs. 10%), with HIV-infected subjects (7% vs. 32%), and with multiple partners (13% vs. 38%) increased. Disseminated tuberculosis increased for men (3% vs. 11%), and women (0% vs. 16%), as well as atypical mycobacteriosis (0% vs. 4% for men, 0% vs. 6% for women). Both sexes had less oral (56% vs 10% and 100% vs. 52%, for men and women, respectively), and esophageal candidiasis (51% vs. 21% and 75% vs. 21%), but the rate of bacterial pneumonia increased among women ((1% vs. 7%), and decreased among men (24% vs. 12%). Diarrhea was less frequent among men (29% vs. 21%) and women (25% vs. 14%): cryptosporidiosis decreased from 13% to 1%among women, and men (5% vs. 2%). I. Belli diagnosis increased in women (0% vs. 4%) and men (3% vs. 5%). Non-Hodkin lymphoma, Histoplasmosis, Cryptococosis, and Citomegalovirus infection were stable (<1%). The reported cases of Kaposis' sarcoma decrease from 8% to 3%.

CONCLUSIONS: In Bahia, Brazil, the clinical and epidemiological trends of AIDS epidemic seem to be different for men and women. The changing epidemiological pattern may be responsible for the clinical discrepancies.

Keywords: AEGIS, Acquired Immunodeficiency Syndrome, HIV Infections, Sarcoma, Kaposi, Sex Characteristics, Tuberculosis, Cryptosporidiosis, Disease Outbreaks, Candidiasis, Brazil, Human, Female, Male, Animal

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C10738