AEGiS-14IAC: Results of testing for human immunodeficiency virus infection among recent contacts to infectious tuberculosis cases.

14th International AIDS Conference


Barcelona, Spain - July 7-12, 2002

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Results of testing for human immunodeficiency virus infection among recent contacts to infectious tuberculosis cases.

Int Conf AIDS 2002 Jul 7-12; 14:(abstract no. MoOrC1101)

Reichler M, Reves R, Mangura B, Bur S, Thompson V, Ford J
Centers for Disease Control and Prevention, Atlanta, United States

BACKGROUND: Persons with recently acquired latent tuberculosis (TB) infection and human immunodeficiency virus (HIV) co-infection are at high risk of rapid progression to TB disease.

METHODS: To determine the proportion of close contacts (CC) to infectious TB cases tested for HIV, and the results of HIV testing for this group, health department records were reviewed for all CC of 349 culture-positive pulmonary TB cases reported in 1996 from five study areas in the US.

RESULTS: A total of 1,169 CC were identified for 349 cases of active pulmonary TB. HIV test results were available for 224 (64%) cases and 220 (19%) CC. Of the cases tested, 164 (73%) were HIV(-) and 60 (27%) were HIV(+). An equal proportion of CC to HIV(+) and HIV(-) cases were tested (21% versus 24%). Of the CC tested, 201 (91%) were HIV(-) and 19 (9%) were HIV(+). Of the 220 CC tested, 177 (80%) were associated with TB cases with known HIV status. Compared with CC of HIV(-) cases, CC of HIV(+) cases were more likely to be HIV(+): No. CC HIV positive / no. tested (% positive) by case HIV status [table: see text]

CONCLUSIONS: Our study identified CC of HIV(+) TB cases as a high risk group for HIV infection. HIV(+) TB cases and their CC may share some of the same risk factors for HIV infection. These findings suggest that the HIV status of the TB case (in addition to established risk factors for HIV infection) may be an important consideration for prioritizing HIV counseling and testing efforts among CC to infectious TB cases. Further studies are needed to identify barriers to HIV testing among CC to infectious TB cases.

Keywords: AEGIS, Tuberculosis, HIV Infections, Tuberculosis, Pulmonary, Risk Factors, HIV Seropositivity, Research Design, Counseling, Mass Screening, Homeless Persons, Greece, HumanKWDaegis,tuberculosis,hivinfections,tuberculosis,pulmonary,riskfactors,hivseropositivity,researchdesign,counseling,massscreening,homelesspersons,greece,human

020707
MoOrC1101

Copyright © 2002 - International AIDS Society (IAS). Reproduction of this abstract (other than one copy for personal reference) must be cleared through the IAS.