AEGiS-14IAC: Condom effectiveness in reducing heterosexual HIV transmission.

14th International AIDS Conference


Barcelona, Spain - July 7-12, 2002

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Condom effectiveness in reducing heterosexual HIV transmission.

Int Conf AIDS 2002 Jul 7-12; 14:(abstract no.. MoPeD3571)

Edudzie EK
YouthAIDS Foundation, Ghana, Accra, Ghana

BACKGROUND: The amount of protection that condoms provide for HIV and other sexually transmitted infections is unknown. When some individuals use condoms and some do not, namely some individuals use condoms 100% of the time and some never use (0%) condoms, condom effectiveness can be estimated by comparing the two incidence rates. Condom effectiveness is the proportionate reduction in disease due to the use of condoms. The objective of this review is to estimate condom effectiveness in reducing heterosexual transmission of HIV.

METHOD: Data collection and analysis: Sample sizes, number of seroconversions, and the person-years of disease-free exposure time were recorded for each cohort. If available, the direction of transmission in the cohort (male-to-female, female-to-male), date of study enrollment, source of infection in the index case, and the presence of other STDs was recorded. HIV incidence was estimated from the cohorts of "always" users and for the cohorts of "never" users. Effectiveness was estimated from these two incidence estimates.

RESULTS: Of the 4709 references that were initially identified, 14 were included in the final analysis. There were 13 cohorts of "always" users that yielded an homogeneous HIV incidence estimate of 1.14 [95% C.I.: .56, 2.04] per 100 person-years. There were 10 cohorts of "never" users that appeared to be heterogeneous. The studies with the longest follow-up time, consisting mainly of studies of partners of hemophiliac and transfusion patients, yielded an HIV incidence estimate of 5.75 [95% C.I.: 3.16, 9.66] per 100 person-years. Overall effectiveness, the proportionate reduction in HIV seroconversion with condom use, is approximately 80%.

CONCLUSIONS: This review indicates that consistent use of condoms results in 80% reduction in HIV incidence. Consistent use is defined as using a condom for all acts of penetrative vaginal intercourse.

Keywords: AEGIS, Heterosexuality, Condoms, HIV, HIV Infections, HIV Seropositivity, Incidence, HIV Seronegativity, Condoms, Female, Coitus, HIV Antibodies, Female, Male, Human, transmission, immunologyKWDaegis,heterosexuality,condoms,hiv,hivinfections,hivseropositivity,incidence,hivseronegativity,condoms,female,coitus,hivantibodies,female,male,human,transmission,immunology

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MoPeD3571

Copyright © 2002 - International AIDS Society (IAS). Reproduction of this abstract (other than one copy for personal reference) must be cleared through the IAS.