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15th International AIDS ConferenceBangkok, Thailand - July 11-16, 2004 |
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10153)
Gordeiko VA, Vashchuk V
Brest state university, Brest, Belarus
BACKGROUND: Amebiasis abscesses of liver normally are caused by Entamoeba histolitica and found in warm climates. Spreading of AIDS leads to emerging of new patients who exhibit both somatic pathology of liver and HIV-infection. Affection of the digestive system by the opportunistic infection is the main reason of mortality of the patients with AIDS in Africa.
METHODS: The work analyses results of treatment using low-invasive surgical method of 52 HIV-infected patients with amebiasis abscesses of liver in Burundi. Ultrasound diagnostics of the abscesses, as well as biochemical and physical data were used. Main location of the abscesses proved in the 5th and 8th segments of the right lobe of liver. Treatment of small abscesses (2-4 cm) was based on metronidazol and wide-spectrum antibiotics. Large abscesses were additionally treated with transcutaneous puncture under ultrasound monitoring. After removing of pus the abscess' cavity was rinsed with 0.5% metronidazol solution and drained.
RESULTS: All patients showed presence of HIV-infection; AIDS was diagnosed at 40% of all patients. Most of the patients (77%) recovered from abscess of liver as a result of this type of treatment; 17.5% died due to progress of AIDS in the course of 1 year, 3 patients demanded operative surgery treatment.
CONCLUSION: Our data show that clinical symptoms of the amebiasis affection of liver at patients with HIV- infection are often treated as consequences of the latter. This leads to progressing of amebiasis abscesses and worsening of the clinical condition of the patient. Low-invasive methods of treatment at patients with HIV- infection are preferrable given they permit to escape operative surgery and connected complications. Our data show that transcutaneous puncture under ultrasound control may serve as a very useful tool in treatment of the patients with amebiasis abscesses of liver complicated with HIV-infection.
040711
B10153
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