AEGiS-15IAC: Profile of tuberculosis (TB) with HIV-AIDS in 350 patients at community care center, Mumbai.

15th International AIDS Conference


Bangkok, Thailand - July 11-16, 2004

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Profile of tuberculosis (TB) with HIV-AIDS in 350 patients at community care center, Mumbai.

Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10428)

Golhar DA, Bora PC, Vasvani D, Gogate A
Community Care Centre,Sarvodaya Hospital, Mumbai, India

Tuberculosis is the commonest opportunistic infection seen in patients living with HIV AIDS. The dual epidemic of HIV and Tuberculosis is on the rise. Clinically active Tuberculosis develops in a stage where cell mediated immunity has just started to deteriorate which is reflected by low CD4 count of 200 - 500 /dl.

METHODS: At the community care center established in September 2002, 350patients were admitted for various complaints uptill Jan2004. Retrospective analysis of these cases was done. Observations: 80% patients were diagnosed to have Tuberculosis. Pulmonary Tuberculosis was detected in 49% patients. Extra pulmonary TB detected in 51% of which Abdominal Tuberculosis was detected in 39% patients and 23% patients had Tuberculous meningitis and 20% patient had disseminated T. B. 8% patients were diagnosed to have tuberculous lympadenitis. 10% patient had plueral effusion. 20% of these T. B.patients had drug-induced hepatitis. Moderate to severe irpn deficiency anemia with Mean Hb of all T. B.patient was 8.2 gm%and marked hypoproteinemia with mean serum albumin of 2.3gm%was observed in 60% cases.

CONCLUSION: 1) Extra pulmonary tuberculosis is observed in almost 51% of late symptomatic HIV cases. 2) Patient compliance is very important as most of the patients are in the medicine drop out phase. 3) Integrating immunomodulating drug therapy, antiretroviral therapy and multiple associated factor like anemia, hypo-proteinemia assicoated with nutritional aspect should be corrected for optimal response to anti-TB therapy. 4) Early diagnosis, timely prophylaxis and patient cooperation go hand in hand.

Keywords: AEGIS, Acquired Immunodeficiency Syndrome, Tuberculosis, HIV Seropositivity, Tuberculosis, Pulmonary, CD4 Lymphocyte Count, HIV Infections, Anti-HIV Agents, Humans, therapy

040711
B10428

Copyright © 2004 - International AIDS Society (IAS). Reproduction of this abstract (other than one copy for personal reference) must be cleared through the IAS.