AEGiS-15IAC: Survival among AIDS patients by situations before and after HAART availability at STD/AIDS training and referral center, Sao Paulo, Brazil.

15th International AIDS Conference

Bangkok, Thailand - July 11-16, 2004

Survival among AIDS patients by situations before and after HAART availability at STD/AIDS training and referral center, Sao Paulo, Brazil.

Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. MoOrD1088)

Gianna MC, Kalichman AO, Bueno SM, Basso CR, Ruiz EA, Tayra A, Santos NJ, Holcman MM
Centro de Referencia e Treinamento DST/AIDS - SES-SP, Sao Paulo, Brazil

BACKGROUND: The STD/AIDS Training and Referral Center (CRT-DST/AIDS) has a specialized service for treating STD/HIV/AIDS patients. The aim of the present study was to estimate survival among patients diagnosed with AIDS from 1992 to 1998 by risk situation at CRT-DST/AIDS.

METHODS: Information on risk situation was collected for all AIDS adult patients at CRT-DST/AIDS from 01/01/1992 to 01/12/1998. Survival was measured until death. Patients who were still alive or lost of follow up were censored at 12/31/2002. The Kaplan Meier Product Limit method was used to estimate survival and the logrank test was performed to achieve differences among groups. To compare the survival among AIDS patients diagnosed before and after HAART availability (2nd half of 1996) the time was divided in two periods one from 1992 to 1995 and the other from 1996 to 1998

RESULTS: The risk category Homosexual/Bisexual represented 43% of patients, Heterosexual 33% and IDU 22%. For 75% of patients estimated survival was 6 months for the first period and 43 months for the second. In the first period the survival curves between the risk situation for HIV infection showed no differences (p=0.09). In the second period the were differences among the survival curves by risk categories (p<0.001) (figure 1).<IMG SRC="images/prog/MoOrD1088_IMG01.jpg" border=0>Conclusion The survival time increased for all risk situation after HAART availability. The difference in the vulnerability to death among the risk situations after HAART will further explore to access issues like education and other socio economic and demographic indicators, prevqalence of other causes of death (e.g. violent death among IVDU), time of HIV infection, frequency of visits to the service/missing visits, prescription and compliance to ARV. Health services must evaluate the approach to HIV/AIDS patients infected trough IV drug use and develop strategies aimed to improve their survival time.

Keywords: AEGIS, Antiretroviral Therapy, Highly Active, Acquired Immunodeficiency Syndrome, HIV Seropositivity, HIV Infections, Bisexuality, Homosexuality, Survival Analysis, Survival, Brazil, Adult, Humans, education, mortality

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