Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10002)
Bharti R, Bharti P;;;; BDC Research Ceter,AAG, Amritsar, India
HIV already has 4.6 m victims (Officially) in India and everyone in authority or otherwise knows that managing these victims and their problems by government efforts alone is like trying to reach moon on foot. Despite the increasing numbers the basic issues remain to be solved. The issues are-are these numbers
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10008)
Ovung Mhabemo E;;;; Hospital, Dimapur, India
Nagaland is situated in the northeastern part of India bordering Myanmar . It is one of the sixth high prevalent states in India. Dimapur is the commercial hub of Nagaland and it has the highest prevalence of HIV/AIDS/STDs in Nagaland. The ongoing campaign against HIV/AIDS/STD at Dimapur is gaini
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10013)
Waikwa SW;;;; Itemeini Organic Farming Self Help Group, Othaya, Kenya
Background. Agro-chemicals and their subsequent abuse are greatly contributing to learning and development disabilities to children affected by the HIV AIDS scourge in Kenya . In the recent past, it has been noted that agro-chemical abuse has seen to the rise of multiple problems to children of school age who are eithe
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10019)
Mosam A, Coovadia HM, Cassol S, Friedland GH, Scadden DT, Cassol E, Page T, Bodasing U, Dawood H, Aboobaker J, Jordaan JP, Lalloo UG;;;; Nelson R Mandela, Durban, South Africa
HAART has decreased the incidence of Kaposi s sarcoma (KS) in the West and has been successful as therapy in isolated reports. There are no prospective trials on HAART as KS therapy. 1. To document the clinical response of HIV KS to HAART ( d4T ,
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10024)
Dragovic G, Jevtovic DJ;;;; Department of Clinical Pharmacology, Pharmacology and Toxicology
Efficacy of Indinavir (IDV) has been known for more than 6 years. Its major disadvantages are limited absorption, a short elimination half-life and adverse events such as nephrolithiasis. IDV in combination with ritonavir (RTV) is believed to ameliorat
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10029)
Swamy GA, Swamy KG;;;; John Paul Slum Development Project, Pune , India
John Paul Slum Development Project is secular voluntary organisation basically working for the well being of slum dwelling PLWHA in Pune- India for those who are socially-economically downtrodden and neglected by the community wherein prevalence and incidence rate is on hike day to day due to their ignoran
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10034)
Kwalombota KM, Shumba CD;;;; Ndola Central Hospital, Ndola, Zambia
OBJECTIVES: HIV testing in paediatrics is standard practice. The psychological consequence of a positive test in a child can be far reaching. It maybe worse in resource limited settings, because only minimal interventions are taken in the management of the children. The study tried to find out the factors that can infl
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10039)
Olley BO;;;; Department of Psychology, Faculty of the Social Sciences, University of Ibadan.l, Ibadan, Nigeria
Objectives: Several programs have been launched by international government and agencies to offer short course antiretroviral drug regimens to reduce mother-to-child transmission (MTCT) of HIV. There is, for example, growing evidence that stress, negative life events and psychopathology contribute significantly to the
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10044)
Sewanyana SV;;;; University, Kampala, Uganda
To assess impact of direct observed therapy programme on rate of infection and cure of T. B among HIV/AIDS patients. In 2001 Mukono AIDS project started a DOT programme as a means of ensuring compliance and adherence to T. B treatment among HIV/AIDS patients attending our clinic abaseline survey
AZT has been routinely offered to HIV pregnant women to prevent HIV transmission from mother to child. Multi-drug ARV regimens are increasingly used for treatment. Viral resistance and its relative role in vertical; transmission and subsequent pediatric clinical course are important to understand especially
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10053)
Mosam A, Thejpal R, Goga Y, Page T, Cassol E, Coovadia HM, Cassol S;;;; Nelson R Mandela School of Medicine, Durban, South Africa
The simultaneous occurrence of KS in mother-child pairs has been documented in only 2 other case reports from Zimbabwe and Zambia . We report the occurrence of KS in mother and child pair from South Africa co-infected with HIV 1 Clade C and Human Herpesvirus 8 (HHV 8) subtype B viral infectio
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10058)
Ngansop Charlotte NC, Kobayashi Eiji KE, Ndembi Nicaise NN, Takemura Taichiro TT, Ido Eiji IE, Takeda Katsumichi TK, Hayami Masanori HM, Kaptue Lazare KL, Ichimura Hiroshi IH;;;; Faculty of medicine and biomedical sciences, university of yaounde I yaounde Cameroon, Yaounde, Cameroon
There has been reported about the prevalence of hepatitisCvirus (HCV) and hepatitis B virus(HBV)in Cameroon . HCV antIbody tets have been reported to miss as much as 39% of HCV infections in prson co-infected with HIV. In this study, to know HIV whether HIV infection can influence onthe infecti
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10064)
Odunukwe NN, Idigbe EO, Adewole TA, Onwujekwe DI, Audu R;;;; Clinical Research Centre Nigerian Instituteof Medical Research, Fedral Ministry of Health, Lagos , Nigeria
To evaluate the effect of a combination of Nevirapine +Stavidine + Lamivudine on Heamatogical and Biochemical values of HIV-1 positive patients in Lagos. Methods and materials: Fifty patients who met the enrollment criteria for accelera
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10068)
Escobar Guevara EE, Monzon de Orozco AO, Mantilla Guevara P, Ochoa Diaz M, Pacheco ME, Marcano de Heras EJ;;;; Bio Cell Laboratory, Caracas, Venezuela
To evaluate the expression of HIV-1 s gp120 in peripheral blood CD4+ T lymphocytes of infected patients as a surrogate marker of disease progression. Methods: Ninety seven patients infected with HIV were studied, analyzing correlation of viral load, T cell subsets, expression of activation markers, antiretr
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10073)
Northfelt DW, Allen A;;;; Mayo Clinic Scottsdale, Scottsdale, United States
Cytolin⢠is an anti-LFA-1 monoclonal antibody (mAb) that may reversibly inhibit CD8+ CTL killing of CD4+ T cells; thus, reducing HIV viral load. Cytolin⢠has no effect on the virus - its method of action is to enhance immunocompetence; thus, evolution of virus subspecies has no effect on the effic
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10078)
Nobahar V, Farid R, Farid F, Abbaszadegan M, Mahmoudi M, Rasteen M;;;; Mashhad University of Medical Sciences, Mashhad, Islamic Republic of Iran
Mashhad, a city in northern Iran , is a newly recognized endemic area for a retrovirus, the Humsn T-cell Lymphotropic Virus Type I (HTLV-I). This virus is the causative agent of a chronic slowly progressive cord syndrome called HTLV-I associated with Humsn T-cell Lymphotropic Virus Type I-asoociated myelopa
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10083)
Ogun SA, Ojini FI, Okubadejo N, Danesi MA, Kolapo KO, Osalusi BS, Brian boyle B;;;; Ogun state university teaching hospital Sagamu, Sagamu, Nigeria
The HIV is neurotropic and clinicians need to be aware of its myriad neurologic manifestations, as these may be the only clinical presentation. This retrospective study aims to evaluate the clinical spectrum and outcome of the neurologic manifestations in patients with HIV / AIDS over a ten year period. Met
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10088)
Ogun SA, Adelowo OO, Familoni OB, Adefuye OB, Alebiosu C, Jaiyesinmi AE, Fakoya EA, Odusan B, Odusoga OL, Ola OO;;;; Ogun State university teaching hospital Sagamu, Sagamu, Nigeria
The HIV epidemics continue to spread and there is dearth of information on the incidence / prevalence, natural history, pattern and progression of the disease in resource poor settings. It is with this background that this retrospective study was carried out to evaluate the changing frequency of HIV / AIDS
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10094)
Shah S, Rana BJ, Rana PS, Kafle S, Shrestha PK;;;; Nava Kiran Plus, Kathmandu, Nepal
Nepal has one of the fastest growing rate of HIV infection in South Asia. With an estimated 60 000 person living with HIV/AIDS the epidemic is concentrated in IDUs which has a staggering HIV prevalence rate of 68% in the capital and more than 40% in general. Lack of immediate targeted intervention may result in
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10099)
Shrestha R, Kc M, Rana A, Kc J, Thapa S, Thapa SM, Karki T, Thapa D, Rana B, Pun G;;;; Nava Kiran Plus, Kathmandu, Nepal
WHO/ UNAIDS estimates that 60 000 people are living with HIV/AIDS in Nepal . Due to poor economic conditions and lack of health care services most of them cannot access ARV therapy. Support groups for PLWHAs can play a vital role in implementing community based ARV treatment programs.
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10104)
Gongora-Rubio F, Gongora DV, Zanon JR;;;; Hospital de Base - Funfarme/ Infectious Diseases Department - Famerp, Sao Jose do Rio Preto -SP, Brazil
Several formulae have been developed in an effort to reduce the toxicity of amphotericin B (Amb), but their high costs preclude widespread use. To evaluate the efficacy of Amphotericin B in a fat emulsion, i.e. Intralipid (Amb-IL) in 37 AIDS patients with cryptococcal meningitis (CM). Patients and methods:
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10109)
Gongora DV, Gongora-Rubio F, Onishi E, Ferreira LC;;;; Hospital de Base - FUNFARME/ Infectious Diseases Department - FAMERP, Sao Jose do Rio Preto -SP, Brazil
Hepatitis B prevention in HIV carriers is important owing to the greater risk of developing the chronic disease and evolving to hepatic cirrhosis earlier than other individuals. The aim of this study was to investigate which population is susceptible to the hepatitis B virus (HBV) amo
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10113)
Lai W, Yin Y;;;; Institute of Dermatology, Chinese Academy of Medical Sciences, Nanjing, China
With the increase in the prevalence of human immunodeficiency virus (HIV) infection in China , there is an urgent need to explore cost-containing methods of HIV antibody detection. L-2 cell line is a T cell line persistently infected with a mutant HIV-1 subtype B strain and come from MT-4 cell line by origi
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10118)
Ginwalla R, Ayles H, Sibande MN, Shanaube K, Siwale M, Kankasa C, Godfrey-Faussett P;;;; ZAMBART, University Teaching Hospital, Lusaka, Zambia
Many resource poor countries with a high burden of HIV are scaling up access to antiretroviral drugs (ARVs). The government of the republic of Zambia has committed to a programme for the delivery of antiretroviral drugs to the whole population. However as ARV s become increasingly accessible, no clear system of
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10123)
Siziakina L, Kuzina T, Andreeva I, Sokolova J, Kharitonova M, Chumacova E;;;; Medical University , Rostov-on-Don, Russian Federation
Polyoxidonium is a high-molecular physiologically active polymer with evident immunotropic action producing powerful stimulating influence over the phagocytic system cells-monocytes and neutrophils - thus leading to an increase of cytokine synthesis and to phagocytosis as well as cytotoxic activity of NK-ce
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10128)
Kraisintu K, Krabbe A, Eksaengsri A;;;; MFN International Limited, London, United Kingdom
Today, six million people with HIV/AIDS are in urgent need of antiretroviral (ARV) treatment in the developing world, 4.1 million of whom live in sub-Saharan Africa. An estimated 6,000 people die of AIDS each day in this region. Although there is no cure for HIV infection, ARV drugs can dramatically reduce HIV-
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10133)
Kraisintu K, Eksaengsri A;;;; Government Pharmaceutical Organization, Bangkok, Thailand
Thailand , an estimated 700,000 people are living with HIV/AIDS. Approximately 20,000 children aged 15 and less requiring ART. The treatment regimen for paediatric patients should mirror those of adults at all level care. This is currently difficult because of the lack of appropriate paediatric formulations. Cl
The use of Fine needle aspiration biopsy rather than excision biopsy in diagnosing the cause of lymphadenopathy in HIV/AIDS patients should be adopted in a resource limited hospitals. Fine needle aspiration is quick, cheaper, easier, and less harmful to the patient. Methods: The study was done in a Ugandan,
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10144)
Owolade OE;;;; Aids Alliance in Nigeria, Lagos, Nigeria
With the advertised and publicised government subsidised antiretroviral therapy for ten thousand (10,000) Nigerians, more people now seek testing without clinical symptoms to which a considerable number of people tested positive. The problem is now on how to cope with the knowledge and the psycho- social issues
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10148)
Miller A, Gray P, Johnson A, Glass S, Waltrip K, Findley M, Holmes K;;;; Community Based Organization, Chicago, United States
Non-adherence to referrals and treatment plans for clients at high-risk for HIV, sexually transmitted diseases and TB is a problem for human service agencies working in medically underserved, low-income Chicago communities. An electronic, linked network of services (LNS) is needed to address this issue. Descrip
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10153)
Gordeiko VA, Vashchuk V;;;; Brest state university, Brest, Belarus
Amebiasis abscesses of liver normally are caused by Entamoeba histolitica and found in warm climates. Spreading of AIDS leads to emerging of new patients who exhibit both somatic pathology of liver and HIV-infection. Affection of the digestive system by the opportunistic infection is the main reason of mort
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10158)
Bajaj L, Saini A, Dubey G, Ranjan R;;;; Institution, Bellary, Karnataka, India
HIV inection has emerged as the most important predisposing factor for developing overt TB in people co-infected with M. tuberculosis . Many of these patients seek help in TB sanatoriums. Although anti retro-viral therapy (ART) is not available to most of them but DOTS is freely available in
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10163)
Patel KK, Patel AK, Patel JK, Shah VN, Mehta NN;;;; ID clinic, Ahmedabad, India
Antiretroviral therapy (ART) is associated with unacceptable long-term metabolic side effects. Methods: Study design: Observational cross sectional study. HIV-1 infected patients completed more than 6 months on ART were looked for metabolic and morphological changes. All patients were followed clinically an
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10168)
Alfonso V, Geller J, Montaner JS;;;; Canadian HIV Trials Network/University of British Columbia, Vancouver, Canada
Accomplishing the goal of antiretroviral therapy, to achieve and maintain an undetectable viral load in plasma, is challenging given that drug regimens require near perfect adherence in order to be effective. To date, most research efforts in the area of adherence have examined adherence problems, and atten
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10173)
Rajasekaran VN;;;; Meenakshi Mission Hospital and Research centre, Madurai, India
To evaluate the treatment outcome amongst HIV 1 positive patients with a combination of ART drugs under the protocol given by CDC, Atlanta. Design: The study population comprised of 150 patients admitted in the AIDS clinic run by MMHRC. Prior to treatment, the clinical history, personal particulars. 10 ml of
Cryptococcosis is the most frequent, life-threatening meningitis in AIDS. It s frequency declined less then other s opportunistic infections after introducing HAART. The mortality and morbidity rates are still high despite treatment. Methods: Medical records of 413 HIV-infected patients (pts) hospitalized b
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10182)
Adwan ZS;;;; Damascus, Swaida, Syrian Arab Republic
Introduction: Hepatitis C virus (HCV), recognized since 1989, is a major health problem worldwide. Infection with hepatitis C virus is one of the most common causes of chronic liver disease. Syria is a developing country with low prevalence of human immunodeficiency virus
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10187)
Sow PG, Gueye PM, Diouf M, N'diaye M, Traore I;;;; Institut d'hygiene Sociale (polyclinique), Dakar, Senegal
The cause of ARV treatment failure in HIV infection is multifactorial and may involve poor adhesion, low drug levels,resistant HIV strainsand others demographic or clinical factors. This study is to determine levels of adherence and variables affecting adherence among patients enrolled in our cohort. Method
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10197)
Lai KK, Manchester G;;;; University of Massachusetts Medical School, Worcester, United States
To compare the incidence of dyslipidemia in HIV-infected patients (pts) on highly active anti-retroviral therapy (HAART) with or without protease inhibitors (PIs) and pts on no therapy. Methods: Demographic and laboratory data of HIV/AIDS pts were retrieved from an electronic database of HIV clinic at UMass
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10202)
Phanuphak N, Chotnopparatpattara P, Chaithongwongwatana S, Santarattiwong P, Kriengsinyot R, U-prasitwong J, Sirisakyot W, Teeratakulpisarn S, Thisyakorn U, Thaithammayanont P, Limpongsanurak S, Phanuphak P;;;; Thai Red Cross AIDS Research Centre, Bangkok, Thailand
MTCT-Plus program introduces practical model of family-centered, multidisciplinary care for HIV-infected patients. While most university hospitals have existing HIV clinics, this model of care may still benefit them by formally organizing the already available services in the hospitals. Chulalongko
Encephalitis from CMV was observed 3 weeks after the initiation of HAART in a patient with advanced AIDS and CMV retinitis suggesting an exaggerated pathologic inflammatory response played a role in the pathogenesis of this presentation. Clinicians should be aware of this potential manifestation of CMV IRS and consider systemic therapy of CMV retinitis in persons with advanced HIV infection if HAART is going to be initiated.
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10212)
Manfredi R, Calza L, Chiodo F;;;; Infectious Diseases, University of Bologna, Bologna, Italy
Gynecomastia (G) is an emerging HAART adverse event. Methods: A cross-sectional survey of ~1000 HIV-infected patients (p) was aimed to identify all cases of G related to >1 year of HAART,and to investigate correlation with demographic-epidemiological variables,clinical-laboratory markers of HIV disease,prio
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10217)
Mirahmadizadeh AR, Ghane Shirazi R, Kadivar MR, Hemmati AR;;;; Shiraz university of medical sciencse, Shiraz, Islamic Republic of Iran
Introduction: HIV infection, transmitted mainly through parenteral and sexual routes, has become one of the major health problems in Asian countries. Drug abusers comprise a major high-risk group in the general population. Methods: To study the prevalence of HIV infection among drug abusers, 1061 drug addicts residing
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10222)
Mulindwa MN, Bateganya M, Kityo C, Ssali F, Mugyenyi P;;;; Joint Clinical Research Center, Kampala, Uganda
The Joint clinical Research Center has pioneered the use of Antiretroviral drugs in Uganda as well as offering comprehensive care to patients with HIV/AIDS. To date, over 12,000 have received ARVs at the center. This is just one percent of all the patients in Uganda who need ARVs. As such management of oppo
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10228)
Cooper DA, Dwyer DE, Workman C, Amin C, Miller J, Hales G, Emery S;;;; Westmead Hospital, Sydney, Australia
NRTI adverse effects may restrict their long term use in HIV-1 therapy. The fusion inhibitor enfuvirtide may be useful in NRTI-sparing treatment regimens, although prospective data on the safety and efficacy of such regimens are limited. Methods: 59 HIV-1 infected, triple treatment class (NRTI, NNRTI, PI) e
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10233)
Sangkitporn DR, Shide DR, Klinbuayaem DR, Leenasirimakul DR, Wirayutwatthana DR, Leechanachai DR, Dettrairat MR, Kunachiwa DR, Thamlikitkul DR;;;; Department of medical sciences, Nonthaburi, Thailand
One of the herbal candidates in the joint research and development between Department of Medical Sciences, Thailand and Kunming Institute of Botany, China is a herbal formulation containing 5 herbs (SH) which has been widely used in China. It was found that each herb and combined SH herbs had anti-retrovira
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10238)
Sherer R, Adeyemi OM, Simeone E, Despotes J, Tschampa J;;;; CORE Center, Cook County Hospital, Chicago, United States
To describe the efficacy, durability and tolerability of Lopinavir/r (LPV/r) based HAART regimens in an urban clinic population. Methods: A retrospective-prospective observational study. Between Oct 2002 and Oct 2003, HIV+ patients currently receiving LPV/r were enrolled in this study. Baseline information
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10243)
Manfredi R, Calza L, Chiodo F;;;; Infectious Diseases, University of Bologna, Bologna, Italy
Notwithstanding the HAART-related change of natural history of HIV,the hospitalization potential of ID wards remains inadequate,according to the continue modification of epidemiology and disease spectrum. Methods: A surveillance study of patients (p) needing hospitalization at our ward and their outcome,was
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10247)
Nissapatorn V, Lee CK, Quek KF, Leong CL, Rohela M, Khairul Anuar A;;;; Department of Parasitology, University of Malaya Medical Centre, 50603 Kuala Lumpur, Malaysia
To determine the seroprevalence of toxoplasmosis among HIV/AIDS patients, and to determine the frequency distribution and the course of toxoplasmic encephalitis among AIDS patients. Methods: We retrospectively reviewed 505 HIV/AIDS patients who attended in the Hospital Kuala Lumpur from the period of Januar
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10252)
Nissapatorn V, Kuppusamy I, Rohela M, Khairul Anuar A;;;; Department of Parasitology, University of Malaya Medical Centre, 50603 Kuala Lumpur, Malaysia
To compare the characteristics of HIV-positive patients with pulmonary or extrapulmonary tuberculosis , and to describe the organ involvement, diagnosis and their treatment. Methods: This retrospective study was conducted at the National Tuberculosis Centre (NTBC) where 252 HIV-positive patients coexisting
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10257)
Lundgren JD;;;; Copenhagen HIV Programme, Copenhagen, Denmark
The efficacy of interleukin-2 boost of the CD4 count is currently tested in controlled trials designed to show improved clinical outcome - the ESPRIT and SILCAAT trials. Observational studies provide a valuable source for estimating clinical event rates for controlled trials, although issues to consider in
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10262)
Rabkin M, Abrams EJ, El-Sadr W;;;; Columbia University, New York, United States
The Columbia University MTCT-Plus Initiative provides HIV/AIDS care and treatment to women and families in resource-poor settings. More than 400 multidisciplinary team members in 8 countries have been trained to provide family-focused HIV/AIDS primary care, OI prophylaxis, and ART to adults and children. Adhere
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10268)
Harry TC, Stuart H, Wright M, Williams M, Brett B;;;; Bure Clinic,James Paget Healthcare NHS Trust, Great Yarmouth, United Kingdom
A 26 years old white female was diagnosed HIV-1 in October 1995. Baseline CD4 count was 50 cells/ mu l. She started AZT , DDI in November 1995. Treatment was modified due to drug reactions from 1996 - 2001. After Virco VirtualPhenotype ⢠she started D4T, DDI &
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10273)
Lee LS, Panchalingam A, Yap MC, Paton NI;;;; Tan Tock Seng Hospital, Singapore, Singapore
When co-administered with ritonavir 100mg, lower doses of indinavir than the conventional 800mg may provide equally effective but less toxic drug levels in Asian HIV-infected patients. Methods: Pharmacokinetic parameters were measured in patients who red
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10278)
Kalyesubula R, Bekunda R, Kibaalya W, Namubiru D, Haag A, Camilo M, Foex JM;;;; Associatio Francois Xavier Bagnaud, Kampala, Uganda
Uganda was one of the first countries in sub-Saharan Africa to experience the devastating impact of HIV/AIDS. Although the Ugandan government has taken important steps to control the epidemic, there still exist gaps in access to care and treatment for people living with HIV/AIDS (PLWA) in rural and undeser
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10283)
Enzama AR, Mugyenyi P, Kityo C;;;; Joint Clinical Research Centre, Kampala, Uganda
Background;The diagnosis of HIV-1 infection in neonates born to sero positive mothers presents two major dilemmas; the presence of maternal antibodies that preclude the use of serological tests, and the difficulty or impossibility of obtaining large volumes of blood for culture. Objectives;To evaluate a reliable method
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10288)
Rodkjaer LR;;;; Skejby Hospital, Aarhus, Denmark
Successful treatment of hiv with HAART requires that patient maintain nearly perfect adherence to the prescribed regimen. Suboptimal adherence is clearly the most common cause of virologic failure of HAART regimens. The purpose of the study was to explain how patients living with hiv manage their interactin
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10293)
Gulotta HC, Troncoso AR, Rodriguez Rios E;;;; Francisco Muniz Hospital, Buenos Aires, Argentina
KS represented the AIDS-defining diagnosis in the early years of the epidemic. It cannot be distinguished with certainly from other vessels tumors, without the use of biopsy. From January 1, 1990, to December 31, 2002, files of 159 adult HIV-infected patients (pts) derived for KS, based on clinical criteria
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10298)
Maher D, Borgdorff MW, Boerma JT;;;; World Health Organization, Geneva, Switzerland
HIV is fuelling the tuberculosis (TB) epidemic and TB is a leading cause of illness and death among people living with HIV/AIDS (PLWHA). Interventions to control HIV-related TB comprise measures against both TB and HIV. How well are we doing in high HIV prevalence countries in implementing the interventions
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10303)
Marne U;;;; Soudamini Network, Mumbai, India
Scares about the spread of HIV coupled with interventions targeted at people who may be seen as reservoirs of infection can lead to stigmatization of people living with HIV and may further marginalize vulnerable communities like women with children which account to almost half the HIV infected population. HIV diagnosis
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10308)
Kekitiinwa AR, Kalyesubura I, Bakeera SK, Namale A, Musoke P;;;; Mulago hospital, Kampala, Uganda
The Paediatric Infectious Disease Clinic is a specialized AIDS clinic established in 1985. Currently, it serves 1200 active clients providing primary care, prevention and treatment of opportunistic infections, counseling and nutritional support. Less than 10% of the children receive antiretroviral therapy.
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10317)
Mandali AB;;;; Andhra Medical College, King George Hosptial, Visakhapatnam, India
As there is a change in the pattern of the Epidemiology and the clinical manifestations of viral STIs in the presence of HIV infection, a comparative study of non opportunistic viral STIs among HIV Positive and HIV negative patients of North Coastal Andhra Paradesh of India
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10322)
Grossman Z, Lorber M, Shahar E, Torten D, Levi I, Risenberg K, Chowers M, Istomin V, Averbuch D, Burke M, Engelhard D, Sthoeger Z, Pollack S, Kra-Oz Z, Ram D, Rudich H, Mileguir F, Mendelson E, Maayan S, Schapiro JM;;;; National HIV Reference Lab, PHL, MOH, Tel Hashomer, Israel
An algorithm based on the number of specific subtype-B protease gene mutations is commonly used to interpret resistance assay results and predict the response to LPN/RTN. Subtle differences present in the protease gene of non-subtype B patients might influence resistance to LPN/RTN. We compared virological
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10327)
Touhon MT, Koffi AC;;;; Centre Plus de Ruban Rouge Cote d'Ivoire, Abidjan, Cote d'Ivoire
Created in 1997 and recognized PLHA centre opportunistic infections follow up by UNAIDS , the Centre Plus (CP) is a daily hospital which ensures free medical and psychosocial support to over 500 PLHA. Anxious the become of patients lost of sight and being in a bad health, the CP initiated from January 2002 to Se
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10332)
Touhon MT;;;; Centre Plus de Ruban Rouge Cote d'Ivoire, Abidjan, Cote d'Ivoire
To make it possible for PLHA to have access to the treatment, Ruban Rouge CI created the Center More in order to ensure a continuum of care of accessible and free quality. The CP has a Community pharmacy which delivers drugs free to the patients after medical consultation. Since November 2002, pharmacy is manage
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10338)
Vaswani DV, Gogate AS;;;; Mumbai Districts AIDS Control Society, Mumbai, India
The of shunning away of PLWH/A by the staff of the hospitals was not an uncommon phenomenon in the city of Mumbai. To overcome this various training programes for all the categories were undertaken which brought a little change in the attitude of the hospital staff. Development of Core Committee and Drop-in
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10343)
Ndiaye I, Sow PS, Gueye NF, Diouf LM, Gueye PM, Bassene E, Kane NC, Diaw A, Mboup S;;;; Hospital, Dakar, Senegal
Determine the feasibility of this treatment. Determine clinical efficacy and safety of this therapy. Methodology: This a prospective open study for 96 weeks, including subjects with HIV1+, over 18 years old at B or C stage with CD4 less 350cells/mm3, ARV therapy naive and who accepted after informent consent
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10348)
Klewer J, Lauschke H, Sekula S, Guillen-Grima F, Aguinaga-Ontoso I, Tracogna U, Kugler J;;;; Public Health, Dresden Medical School, Dresden, Germany
To prevent occupational HIV infections in health professionals, comprehensive knowledge about HIV/AIDS is essential. Due to working close to infected patients, especially nursing staff is endangered. Therefore, the study tried to investigate how nursing staff from countries with different HIV prevalences as
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10353)
Clevenbergh P, Sellier P, Mazeron M, Cazals-Hatem D, Evans J, Cervoni J, Badsi E, Bendenoun M, Diemer M, Vincent V, Caulin C, Bergmann J;;;; Internal Medicine Dpt, Lariboisiere Hospital, Paris, France
Introduction: Ten % of HIV-infected individuals are hepatitis B virus (HBV) surface antigen-positive (HBs Ag). First line anti-HIV therapy usually contains lamivudine ( 3TC ), a reverse transcriptase inhibitor with antiviral activity against both HIV and HBV.
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10358)
Lynen LM, Phan S, Suos P, Thai S, Harwell J, Boelaert M;;;; Institute of Tropical Medicine, Antwerp, Belgium
Hyponatremia is frequent in hospitalized HIV patients. This seems particularly true for HIV patients with extra-pulmonary tuberculosis (EPTB). EPTB is difficult to diagnose in resource-poor settings. We studied the predictive value of hyponatremia for the diagnosis of EPTB in a cohort of HIV patients. Metho
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10362)
Fallon SJ;;;; Skills4, Inc, Ft Lauderdale, FL 33305, United States
Treatment update conferences typically offer medical providers specific treatment durability data. This workshop is designed to help PLWH to understand the important role that a patient s lifestyle choices make in managing HIV, and also to help physicians, nurses, and case managers improve their ability to expl
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10367)
Diaz Oropeza IF;;;; Fundacion Mexicana para la luch contra el SIDA, A.C., Mexico City, Mexico
WHO considers that care involves biopsychosocial aspects and some authors describe this like a comprehensive approach to care of PWA. The complex nature of HIV/AIDS care is the best argument for enhancing collaboration between health providers, mental health professionals and families living with HIV/AIDS. Desc
This is a descriptive study to explore nursing care provied to AIDS patients with Cryptococcal menigitis based on their health problems and needs and to examine the correlation between patients taught by nurses and the three factors,patients recovery,re-admission and follow-up rate. The sample consisted of 462 AIDS pat
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10377)
Rasania SK, Singh RN;;;; Department of Community Medicine V.M. Medical College and Safdarjang Hospital , New Dehli, India
HIV/AIDS is among the top killer disease, worldwide. Health Care Providers (HCPs) have to protect themselves from HIV/AIDS. They have to provide, to unfortunate persons suffering from HIV/AIDS; care and full emotional support. This depends on their knowledge about this subject. But are they willing to provi
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10382)
Erhabor O, Ejele OA, Nwauche CA;;;; Department of Haematology and Immunology University of Port Harcourt PMB 1 Choba , Port Harcourt, Nigeria
Highly active antiretroviral therapy (HAART) has changed the landscape of HIV related care in the developed world but its benefits have not been well elucidated especially among Africans. In this study, we have compared the immunological response to HAART in Africans based on starting baseline CD4 count. Me
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10387)
Kunda WV;;;; Kabwe DHMT, Kabwe, Zambia
There has been more women involvement in support group activities, primarily because of their significant role as care givers and as pillars at both family and community levels. Those with the expectation that the same service would be provided to them in time of need. The support groups surveyed relied exclusi
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10392)
Casseb J, Veiga AP, Duarte AJ;;;; FMUSP, Sao Paulo, Brazil
After successful HAART, there are increased numbers of T CD4+ memory and naive cells, and there is an improvement of antibody response to new antigens. We studied the efficacy of vaccination against HBV in HIV-1-infected subjects on HAART and analyzed the factors involved in the failure. Methods: 55 HIV-1-i
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10397)
Chihrin S, Loutfy MR, Raboud J, Saskin R, Govan V, Dimayuga R, Rachlis A, Kovacs C, Crouzat F, Tilley D, Chang B, Phillips E, Walmsley S, Fletcher D;;;; Canadian Immunodeficiency Research Collaborative, Toronto, Ontario, Canada
To determine the utilization of liver biopsy and effectiveness of interferon (IFN) (regular and pegylated) plus ribavirin (RBV) in HIV/HCV co-infected patients. Methods: A retrospective chart review was completed for 151 HIV/HCV co-infected patients from 2 Toronto centres. Reasons for and treatment decision
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10402)
Sommers EA, Porter KE;;;; AIDS Care Project, Boston, United States
Acupuncture has demonstrated efficacy in managing digestive side-effects of medications used in cancer chemotherapy and following anaesthesia. This clinical trial examines the role of acupuncture in controlling side-effects related to the use of highly active antiretroviral therapy (HAART). HAART therapy re
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10408)
Chang LW, Phipps WP, Kennedy GE, Rutherford GW;;;; University of California, San Francisco, San Francisco, United States
Cryptococcal disease is a major source of morbidity and mortality in persons with HIV, particularly in the developing world. In this systematic review, the efficacy of antifungals for the primary prevention of cryptococcal disease in persons with HIV will be assessed. Methods: We searched for randomised con
HIV-associated lipodystrophy syndrome(LD) is a recently recognized syndrome characterized by morphologic and metabolic changes observed during antiretroviral therapy(ART). The morphologic change can be highly stigmatizing and the metabolic manifestation may contribute to a range of morbidities. The objectiv
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10417)
Gulotta HC, Espinosa G, Levi N, Cacciavillani M, Cazalla L, Rossi ML, Monteagudo M, Troncoso AR;;;; Infectious Diseases Francisco J Muniz, Buenos Aires, Argentina
Malnutrition is common among individuals suffering advanced HIV disease. The purpose of this work was to assess the impact of HIV infection on nutritional status. Methods: Prospective single-center observational study of 124 pts. Anthropometric parameters (weight, size, and arm muscle circumference, tricipi
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10422)
Choi JY, Chang KH, Park YS, Cho CH, Shin SY, Han SH, Choi SH, Chin BS, Park YS, Song YG, Kim JM;;;; AIDS Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea
Metabolic complications of indinavir, such as lipodystrophy or hyperlipidemia, are rare in Koreans. We evaluated whether the pharmacokinetic parameters of indinavir in Koreans and Caucasians differ. Materials and Methods: Indinavir 800 mg was administered orally to eight healthy male Koreans and four health
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10428)
Golhar DA, Bora PC, Vasvani D, Gogate A;;;; Community Care Centre,Sarvodaya Hospital, Mumbai, India
Tuberculosis is the commonest opportunistic infection seen in patients living with HIV AIDS. The dual epidemic of HIV and Tuberculosis is on the rise. Clinically active Tuberculosis develops in a stage where cell mediated immunity has just started to deteriorate which is reflected by low CD4 count of 200 - 500 /dl. Met
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10432)
Sims R, Eriki M, Awori M;;;; Jajja's Home Mildmay International, Kampala, Uganda
Issue : Care for children living with AIDS is not a priority in many resource limited settings, resulting in children dying prematurely, unnecessarily and in distress. Rehabilitation, in the form of holistic palliative care, can restore the health of many children to a point where they can benefit from anti-retroviral
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10437)
Nguyen NL;;;; Faculty of Medicine, Hue, Vietnam
Background:The CD4 count is being used to evaluate the immune status of HIV- infected person, but it is too expensive to become popular in developing countries. The DNCB (Dinitrochlorobenzen) skin test has been used by immunologist to evaluate the cell-mediated immune response. Some investigators proposed some blood pa
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10442)
Zverev SY, Alikina YI, Novikova OV, Zemskova EA;;;; Regional AIDS Centre, Perm, Russian Federation
Of 4,915 HIV-infected persons registered on the 1-st of January, 2004, in Perm region, 29,5% were women of fertile age and co-infected with HIV-1 and HCV. To evaluate risk of HCV maternal transmission to babies exposed to both viruses we have investigated all cases of childbirth among these women. Methods:
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10452)
Rathod UL;;;; Institution, Surat, India
Controlling STDs and HIV/AIDS in a city of 2.5 million inhabitants through counseling, complete treatment, contact treatment and condom promotion within the existing health apparatus. Instead of a target group focused approach adoption of an overarching umbrella approach covering various occupational and social
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10457)
Metadilogkul O, Jirathitikal V, Bourinbaiar AS;;;; 1Occupational and Environmental Medicine Association of Thailand, Rajavithi General Hospital, Bangkok , Thailand
As there is still neither a cure for the acquired immunodeficiency syndrome (AIDS) nor a vaccine to prevent human immunodeficiency virus (HIV) infection, an AIDS diagnosis remains associated with death sentence. Thailand is one of South-East Asian countries with high prevalence of HIV infection, where most
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10462)
Janse van Rensburg E, Lotter S, Wilsdorf L, Robson B, Canosci A;;;; University of Stellenbosch and National Health Laboratory Service , Tygerberg, South Africa
Comparison of the performance of the Abbott HIV Ag/Ab Combo (Combo) assay that detects both HIV antibodies and p24 antigen to the Abbott Axsym HIV 1/2 gO (gO) assay that only detects HIV antibodies, in a public hospital setting in Cape Town, South Africa . Methods: The following samples were tested: 300 rou
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10467)
Arana FE, Hernandez DB, Aguilar JS, Campoyo E, Branson B, Mejia C, Arathoon E, Samayoa B;;;; Universidad del Valle de Guatemala, Guatemala, Guatemala
Recent advances in the areas of rapid test for HIV have resulted in the availability of new, simple rapid tests that are suitable for use in settings with limited technical resources. OBJETIVES: Evaluate the feasibility and reliability of a strategy using two or three rapid tests for confirmation of test re
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10473)
Galpin LE, Tebas P, Gomez B;;;; Washington University in St. Louis, St. Louis, United States
The adult prevalence rate of HIV infection in Puerto Plata was estimated to be 4.5% in 1999, significantly higher than the national prevalence rate of 2.8%. Among antenatal women in Santo Domingo, the capital city, UNAIDS /WHO estimated the HIV prevalence rate to be between 1 and 2% between 1991 and 1998. I
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10478)
Wandee P, Supawitkul S, Pinta N, Ngoentong Y, Khunkonkapan S, Kaewkampa P, Sumanapun S, Levine W, Sinsomboontong S, Mednavyn T;;;; Chiang Rai Provincial Health Office, Chiang Rai, Thailand
Dual TB and HIV/AIDS epidemic is common especially in developing countries. Inter-country cooperation is still less addressed. Method: We reviewed TB/HIV patient data in a Thailand community hospital. The hospital provided TB and HIV care for patients living in the border area of Thailand and
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10483)
Wong H, Yu E;;;; Canadian HIV Trials Network, Vancouver, Canada
The time taken for the CD4 cell count to fall below a threshold value is often used as the endpoint in a clinical trial. Deciding whether endpoint has been met based on a single CD4 determination may be inaccurate since the true CD4 count is subject to natural physiologic variation and assay error. Hence in
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10488)
Ilboudo M, Koala DR, Traore M, N'guyen Vinh-kim DR;;;; Association African Solidarite, Ouagadougou, Burkina Faso
Introduction: Projet Orange, fruit of the partnership between Association African Solidarite (AAS) and Alliance Internationale is aimed at developing a strong community based center to expand access to HIV/AIDS treatments in Burkina Faso . It will serve model for the safe and effective use of ARV s. Strategy: The strat
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10493)
Khuong-Josses MA, Chaplain C, Khelil N, Mechali D;;;; Delafontaine Hospital, Saint-Denis, France
Antiretroviral therapy (ART) has contributed to the dramatic decline in MFT of HIV in developing countries. However, zidovudine (ZDV) alone does not fully suppress HIV replication, and chemoprophylaxis with ZDV alone might select for ZDV-resistant viral variants, affecting future response to ZDV-containing regimens. Me
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10499)
Laursen T, Hoegaard A, Ingerslev HJ, Oestergaard L, Kesmodel U;;;; Skejby University Hospital, AArhus, Denmark
In 2002 a concensus was made in Denmark to help HIV discordent couples. Up till 2002 patients were advised not to have children, because of the risk of transmitting the virus to the partner and child, and because of ethical reasons. The antiretroviral treatment has changed this, HIV is now considered a chro
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10504)
Seitaboth S, Brady MF, Lurie M, Akao K, Hendricks K, Pugatch D;;;; Angkor Hospital for Children, Siem Reap, Cambodia
Both malnutrition and HIV are prevalent in Cambodia . To date, the relationship between malnutrition and HIV disease stage has not been well described in Cambodian children, but malnutrition is likely to impact on the course of HIV infection. We examined the relationship between malnutrition, assessed by an
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10509)
Badaru SO, Omilabu SA, Ajayi GO;;;; Virology Research Laboratory, Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos,, Lagos, Nigeria
Vertical transmission of HIV could be minimized or even prevented if adequate preliminary tests including screening and confirmatory tests for HIV-1 & 2 were carried out for spouses (or intending parents) before admission to the antenatal clinic. The preliminary tests would facilitates monitoring and ma
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10514)
Elkashef A, Smith EV, Rawson R, Pearce VJ, Ling W, Vocci FJ, Campbell J, Haning W, Mawhinney J, McCann MJ, Weis D, Johnson B;;;; DHHS/NIH/NIDA, Bethesda, MD, United States
Increased HIV risk behavior has been linked to Methamphetamine dependence among the homosexual population, and has been assessed throughout the clinical studies recently conducted by NIDA, and the Methamphetamine Clinical Trials Group (MCTG). One of the outcomes of these studies is to determine if treatment
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10519)
Cho Y, Lee H, Yang H, Ahn S, Lee H;;;; Asan medical center, University of Ulsan, SEOUL, Republic of Korea
Despite the introduction of HAART in AIDS therapy, HIV-1 infection is still not curable. A variety of immune-based therapies are under consideration to improve immunological functions in HIV-1-infected patients. Ginseng is recorded as the best medicine of all in Shen Nung s Pharmacopoeia compiled between A.
Development of affordable and safe therapy to reverse the loss of body mass is of critical importance since AIDS-related wasting is associated with increased mortality. We have demonstrated earlier that oral therapeutic HIV vaccine, V-1 Immunitor (V1), tested in a small group of AIDS patients in
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10529)
Gutierrez R;;;; Hospital Dr. R.A. Calderon Guardia, San Jose, Costa Rica
General To offer accompaniment (support) to PLWA who take ARV treatment and present adherence problems. Specific Objectives: 1. To accompany to the PLWA in their emotional necessities. 2. To offer counsel and education in HIV/AIDS for PLWA, to improve the ARV adherence. 3. To modify the behaviors that avoids
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10533)
Bialos DS, Cederblom L, Selwyn P, Rivard M, Constantino J;;;; Leeway Skilled Nursing Facility, New Haven, United States
AIDS patients with substance abuse and psychiatric symptoms present treatment difficulties, including poor adherence to complex regimens, impaired judgment and impulse control (J/IC) and maladaptive behavior. Psychiatric comorbidity is a problem in patients with HIV/AIDS who require long term care. We studi
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10538)
Kariyo P, Ntwari RC, Baramperanye E, Mbuzenakamwe MJ;;;; Chu de Kamenge, Bujumbura, Burundi
The advent of antiretroviral therapy allowed reducing mortality and morbidity associated with HIV related diseases. The goal of this study is to evaluate the clinical and immunological effectiveness at one-year treatment of a triple combination of ART in naive children. Methods: A cohort of HIV infected nai
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10544)
Chen SY, Hsu L, Schwarcz SK, McFarland W;;;; Johns Hopkins Bloomberg School of Public Health, Baltimore, United States
The WHO/ UNAIDS plan to treat three million HIV-infected persons by 2005 recommends four antiretroviral drug combinations. We used AIDS surveillance and mortality data in San Francisco to compare the survival experience of persons who initiated treatment using a WHO/UNAIDS versus non-WHO/UNAIDS regimen. Met
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10549)
Panpattanakul S;;;; Phayao Provincial Health office, Phayao, Thailand
To study the treatment outcome and expenses of 91 patients from 142 HIV infected patients who received triple therapy after 1 year of treatment during February 2001 - September 2002 in 6 hospitals of Phayao province. Method: Collecting the data from the existing treatment records (ATC 1) and developing quest
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10554)
Spire B, Carrieri MP, Rey D, Loubiere S, Dujardin P, Mechali D, Cassuto JP, Obadia Y;;;; INSERMU379/ORS, Marseille, France
Background : The need to provide HCV treatment to people co-infected with HIV was addressed in the last international consensus conference about HCV treatment. Until 2002, a liver biopsy was mandatory in France to assess the indication of antiviral therapy for HCV infection. We aimed to identify factors associated with
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10559)
Weigel R, Tauzi J, Thambo L, Hosseinipour M, Neuhann F, Boxshall M, Phiri S;;;; The Lighthouse Centre at LCH, Lilongwe, Malawi
Since the availability of affordable generic syrups and tablets (20-30 US$), HAART for children became an option. Here, clinical course and outcome are described in order to contribute information to the scale up process for this age group. Methods: From 09/02 until 12/03, a prospective observational cohort
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10564)
Paiva V, Ayres JR, Della Negra M, Franica I Jr, Galano E, Segurado A, Lecussan P, Silva M, Lacerda R, Gravato N;;;; Psychology - Univ. Sao Paulo, Sao Paulo, Brazil
The number of adolescents living with HIV/AIDS is increasing in Brazil , due to free access to HAART that enhance quality of life of children who were born with HIV & to sexual infection of adolescents living in vulnerable contexts. Sexual and reproductive health care needs and support for psychosocial
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10569)
McLean CA, Chaowanachan T, Evans-Strickfaden T, van de Wijgert J, Kantipong P, Kilmarx PH, Mock P, Whitehead S, Siraprapasiri T, Hart CE, Tappero JW, Markowitz LE;;;; Division of STD Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, GA, United States
A randomized, controlled, cross-over trial is being conducted to evaluate safety and acceptability of a candidate vaginal microbicide (Carraguardâ¢) among HIV-infected women in Thailand . Eligibility criteria include a CD4 cell count of 50-500 cells/muL and not currently taking antiretroviral therapy. T
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10574)
Chen L, Feng TJ;;;; Shenzhen Center for Disease Prevention and Control, Shenzhen, China
To observe and evaluate the effectiveness of highly active antiretrovirus therapy (HAART) on HIV/AIDS patients by HIV-1 load and T subsets analysis. Methods: Using HIV-1 quantitative RT-PCR methods and immunological function inspection, we monitored 4 HIV/AIDS patients who were suffering from immunological
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10579)
McLean CA, Kantipong P, Chaowanachan T, van de Wijgert J, Medtanavyn T, Braunstein S, Whitehead SJ, Siraprapasiri T, Tappero JW;;;; Division of STD Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, GA, United States
We screened HIV-infected women for participation in a safety and acceptability trial of a candidate vaginal microbicide (Carraguardâ¢) in Northern Thailand . Eligibility criteria include abstinence or a HIV-infected husband or steady sex partner, regular menstrual cycles, not currently taking antiretrov
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10584)
Steel-Duncan JC, Pierre R, Evans-Gilbert T, Rodriquez B, Smikle M, Palmer P, Whorms S, Hambleton I, Figueroa P, Christie CD;;;; University of the West Indies, Kingston 6, Jamaica
In a few Caribbean islands, pMTCT of HIV with zidovudine prophylaxis has reduced transmission rates from 27 - 44% to 5.5 - 9%. This paper highlights the uptake of interventions, preliminary outcomes and challenges in caring for HIV exposed infants in a pMTCT program in a resource-limited setting. Methodolog
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10588)
Logan JA, Barker T, Zafft W;;;; Massachusetts Department of Public Health HIV/AIDS Bureau , Boston, United States
Currently, 7% of the individuals living with HIV/AIDS in Massachusetts, U. S. were diagnosed while in a correctional facility. Statewide, 69% of individuals diagnosed with HIV/AIDS during incarceration were from communities of color compared to 51% of all individuals living with HIV/AIDS. Known HIV+ individuals
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10592)
Gupta VK;;;; Sharan- society for urban poverty, New Delhi, India
To sensitize the government for the importance for continues N/S exchange program in Delhi It is situated at bank of Yamuna River. Sharan have been working in this area since 1998 with the primarily focus of reaching out to the marginalized population from the lowest stature of life and we have been
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10596)
Schmeisser N, Woehrmann A, Qurishi N, Salzberger B, Rockstroh J, Faetkenheuer G;;;; Department of Internal Medicine, University of Cologne, Germany
Previous studies have shown that treatment changes occur frequently in patients initiating HAART for the first time. We were interested in the relationship between treatment changes and virological outcome of these patients. Methods: Prospective observational study of all patients treated in two outpatient c
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10600)
Rosso R, Ferrazin A, Cassottana P, Di Biagio A, Ferrando S, Dentone C, Bassetti M, Chierchia S, Bassetti D;;;; Infectious Diseases Clinic, University of Genoa, S. Martino Hospital, Genoa, Italy
Children born from HIV+ mothers (pts) can develop cardiovascular abnormalities, which may arise from exposure to HIV and/or from ART. We evaluated possible cardiovascular involvement in long-term treated pts. Methods: Quantitative M-mode-2D-Doppler CW-PW-color trans-thoracic echocardiogram (TTE) was perform
As compared to the transfusional practice of Western countries, in Russia blood products per patient are used several times more. A reason for this lies in existence of prescriptions for use of blood products on a scale which may be considered excessive (Molchanov, 1999). In our region, an increase in numbe
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10608)
Bearz A, Vaccher E, Spazzapan S, Berretta M, Spina M, Tirelli U;;;; National Cancer Institute, Aviano (PN), Italy
Lung cancer, one of the most frequent non-AIDS-defining tumors, showed aggressive clinical course in the pre-HAART era. To assess the influence of HAART on HIV-related lung cancer, we retrospectively analyzed 61 cases collected on behalf of GICAT (Italian Cooperative Group on AIDS and Tumors)Clinical data of HIV-infect
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10612)
Adje-Toure CA, Fassinou P, Borget MY, Barouan MC, Diomande F, Maurice C, Nolan M, Nkengasong JN;;;; Projet RETROCI, 01 BP1712 ABJ 01, Cote d'Ivoire
To determine the prevalence of HIV-1 antiretroviral genotypic drug-resistant strains among children receiving antiretroviral therapy (ART) for approximately 1 year in Cote d Ivoire . Methods: Between August 1998 and September 2002, 260 HIV-infected children (age, 0-15 years) received ART in Abidjan. We teste
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10616)
Rosso R, Ferrando S, Dentone C, Di Biagio A, Ferrazin A, Beltrame A, Bassetti M, Bassetti D;;;; Infectious Diseases Clinic, University of Genoa, S. Martino Hospital, Genoa, Italy
Protease inhibitors (PIs) have been associated with metabolic complications in children and adolescent HIV positive patients (pts). Replacement of PIs by efavirenz (EFZ) has been attempted to reduce these toxicities. We analyze the efficacy and evolution of lipid profile after replacing PIs by EFZ in pts be
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10620)
Rafique MA;;;; Vision, Lahore, Pakistan
According to a situational needs assessment commissioned by World Bank and DIFID in Pakistan along with National AIDS Control Program in Pakistan and carried out by Vision Lahore in collaboration with Naz Foundation International in United Kingdom in year 2001, it was discovered that majority of the street
PMTCT program initiated in 1996 led to many orphans after their parents passed away. MTCT-Plus program was set up to provide supports in order to give their parents opportunities to live with their children. Not only medical care, usually only ARV, but also comprehensive care should be provided to them. Every a
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10628)
Kironde S, Munisi W, Ntyangiri E, Msaky H, Wilfert C, Masuki G, Mlay V, Saba J;;;; Axios , Kampala, Uganda
In 2002, PMTCT services were only available at 5 tertiary hospitals in Tanzania and only 30% of antenatal attendees where actually getting counseling and HIV testing. In 2003, the district health authorities, with funding from the Elizabeth Glaser Pediatric AIDS Foundation and technical assistance from Axio
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10632)
Rodriguez C, Sobrino P, Vall M, Alastrue I, Camara MM, Bru F, Varela JA, Junquera ML, del Romero J, Castilla J; Centro Sanitario Sandoval, Madrid, Spain
Vaccination against Hepatitis B virus (HBV) is specially indicated for individuals presenting parenteral or sexual risks. Vaccination coverage and serological situation have been evaluated for various risk population groups. Methods: Transversal study of first time HIV testers in 8 clinics in
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10636)
Pinho Neto OS, Frade JD, Madruga MF, Diniz MG, Oliveira IC, Chacon N, Medeiros F;;;; University Hospital Lauro Wanderley/Federal University of Paraaba, Joao Pessoa, Brazil
This study evaluated the success of service of specialized care (SAE) of University Hospital Lauro Wanderley has with recommendations of a National Program (PNDST/AIDS-MS) for the prevention of mother-to-child transmission (MTCT) of HIV in 46 mother-infant pairs from Joao Pessoa, Paraiba, Brazil . This population
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10640)
Babb DA, Pemba L, Seatlanyane P, Charalambous S, Churchyard GJ, Grant AD;;;; London School of Hygiene & Tropical Medicine, London, United Kingdom
Traditional medicine is widely used in southern Africa. We investigated the use of traditional medicines among HIV-infected individuals attending a workplace clinic in South Africa where an ART programme has recently been launched. Methods: We interviewed clinic attendees with moderate or advanced HIV disea
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10644)
Krain A, Daniel O, Ogun S, Odusoga O, Falola R, Kolapo K, Boyle B;;;; Weill Medical College of Cornell University, New York, United States
Nevirapine related toxicities, including rash and hepatotoxicity, are well described. To decrease the risk of toxicities a 14 day lead in period and careful monitoring are recommended. Increasing availability of nevirapine in countries with limited provider experience or where only fixed-dose drug combinations
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10648)
Hohl CA;;;; Boston Health Care for the Homeless Program, Boston, United States
In the US, urban homeless individuals have a higher prevalence of substance abuse, mental illness and exposure to violence than the general population, making them at increased risk for HIV and complicating management of the disease. Identifying homeless people infected with HIV is difficult but vital. Treatment
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10652)
Sanchez-Montero F, Pascua J, Costo A, Sanchez JF, Sanchez T, Martin C;;;; Hospital San Pedro Alcantara, Caceres, Spain
Chronic hepatitis C is a growing cause of morbi-mortality in HIV infected patients. Therapy of chronic hepatitis C has improved with the introduction of pegylated interferon and ribavirin. Currently, the sustained virologic response is 60% in HIV negative patients. We have evaluated the efficacy and safety
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10656)
McCaffrey M;;;; Kansas City Free Health Clinic, Kansas City, Missouri 64109, United States
After a client is engaged in care several factors can affect the outcome of treatment. they include adhering to antiretroviral therapy, keeping medical appointments, and communicating problems to providers. Linking patients with trained peer counselors can bridge this chasm to improve overall engagement to care
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10660)
Benetucci J, Oliva SM, Metta H;;;; Hospital de Infecciosas F. J. Muniz - FUNDAI, Buenos Aires, Argentina
To assess the clinical features of OE, the correct use of PEP and the evolution of the HCWs. Methods: Prospective study in 202 HCWs. Demografic characteristics, features of the exposures, rational use of PEP and the evolution of HCWs were studied. Results: From 1998 to 2003, 202 HCWs were reported. Women: 1
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10664)
Guelar A, Knobel H, Vallecillo G, Montero M, Gonzalez A, Saballs P, Gimeno JL, Lopez-Colomes JL;;;; Hospital del Mar, Barcelona, Spain
Objective. Limited in vitro data about the use of nevirapine + efavirenz reported controversial results. One clinical trial in naive patients suggests that combination of these drugs obtained poor results than the use of one of them alone, mainly because of adverse
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10668)
Menezes-Padua CA, Bonolo PF, Cesar CC, Guimaraes MD;;;; Universidade Federal de Minas Gerais, Minas Gerais, Brazil
Adverse reactions are frequently reported by HIV-infected patients on antiretroviral therapy (ARV) and they are one of the most common reasons for non-adherence and discontinuation of therapy. However, there is little information in Brazil , where HAART therapy is widely available, on adverse reactions amon
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10672)
Kaddu M, Nabatanzi F;;;; Uganda Prisons Service, Kampala, Uganda
Humane custody as a component of the UPS Mission includes maintenance of an acceptable level of health. The Prisons Health Service is mandated with the control and management of HIV/AIDS. A prisons HIV/AIDS Control Programme (UPACP) was established in 1993 to reduce the spread of HIV/AIDS and addre
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10676)
Beltran MA, Nasiff V, Gil RA, Sanga N, Loza S;;;; Hospital San Isidro, San Isidro, Argentina
AIDS and HIV-1-seropositive patients from Argentina have free access to HAART since 1996. We assist patients from 1987 at our Service. Since march 2002 we included all our patients in a prospective follow-up cohort. We describe in this report events related to HAART during 12 months. to describe: 1- baseline
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10680)
Oswal JS, Lalwani SK, Kalrao VR;;;; Bharati Vidyapeeth Medical College, Pune, India
The HIV infection in children is still a major problem in developing countries like India . We studied clinical spectrum of HIV-infection in children at a tertiary care center. Methods: From October 2001 onwards, 45 HIV-infected children were referred to HIV clinic. All the children were thoroughly examined
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10684)
Sanmaneechai O, Puthanakit T, Louthrenoo O, Sirisanthana V;;;; chiang mai university, chiang mai, Thailand
Uninfected children born to HIV-seropositive mothers (HIV-affected children) are growing up in a non-nurturing environment. The study is aimed at determining the growth, developmental and behavioral outcomes of Thai HIV-affected preschool children. Methods: A cross-sectional study of 30 HIV-affected childre
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10688)
Kasai T, Togawa M, Ohba T, Kunikata T, Ozaki Y, Takayama N, Imura S, Kita T, Taniguchi H, Hayashi K, Tsukahara Y, Wada Y, Minoura S, Abe S, Sakumoto K, Takano M, Hasuo Y, Hayakawa S, Kitamura K, Yoshino N, Inaba J, Totani R, Inaba N;;;; Department of Pediatrics, Iwate Medical University, Morioka, Japan
Our study purpose is to clarify and describe mother-to-child transmission (MTCT) of HIV-1 in Japan . Method: Clinical information regarding 193 live births born from HIV-1 positive mothers from 1984 through to 2002 was analyzed retrospectively. Results: MTCT rate was 15.5% (30/193) in total. According to th
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10692)
Oparaugo CT, Idigbe EO, Onyewuche JI, Adetiloye EB;;;; Nigerian Institute of Medical Research , Yaba, Lagos, Nigeria
This study was carried out between January and December 2002 to determine the prevalence of Salmonella and Shigella species in the stool of HIV positive patients with diarrhoea in Lagos, Nigeria . Method: Stool samples of 116 confirmed HIV positive patients with diarrhoea were collected and screened for Sal
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10696)
Alaei K, Alaei A, Saeydi M, Mansoori D, Vaziri S;;;; HIV/STI/IDU Counseling & Care center, Kermanshah, Islamic Republic of Iran
One of the main barriers for starting HAART for HIV/IDUs is the misbeleif that they have less adherence to HAART. Methods: In this study 27 HIV infected cases with CD4
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10700)
Lemanska LM, Jankowska JM, Smiatacz ST, Trocha TH;;;; Medical University of Gdansk, Department of Infectious Diseases, Gdansk, Poland
Background : To study the effectiveness of HAART in observed HIV-infected patients. Material and methods : The study included 131 HIV- infected patients receiving HAART in the Department of Infectious Diseases Medical University of Gdansk between 2001 and 2003. The analysis was performed on patients being under regular
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10704)
Mussini C, Bedini A, Borghi V, Cossarizza A, Esposito R;;;; Clinic of Infectious Diseases, Modena, Modena, Italy
In clinical practice it seems that the tolerability, the incidence of side effects and the reason for discontinuation of NNRTIs could be higher than described in the literature. Methods: Retrospective cohort study. An accurate chart review was conducted to evaluate the onset of any side effect related to tr
Metabolic side effects are common with several anti-HIV drugs. Tenofovir disoproxil fumarate (TDF), a non-nucleotide reverse-transcriptase inhibitor, seems to be free of significant toxicity of that kind, although data are scant.
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10712)
Panpanich R, Leuseree T, Rumakom P, Baker S;;;; Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
In the upper north of Thailand , the Access to Care project for provision of antiretroviral therapy was launched in the year 2001. The first cohort took place in 54 hospitals with 819 PLHA. The evaluation study was conducted one year after the ATC project started in 15 hospitals of 5 provinces in N
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10716)
Deng XW, Terunuma H, Munkanta M, Jin HF, Gondwe C, Yamashita A, Kasai H, Kato S, Saito Y, Takashima Y, Hanabusa H, Fujii T, Ishikawa M, Sakai M, Shirahata S, Oka S, Takahashi S, Ikeda S, Miura T, Matuda J, Ito M, Mimaya J;;;; Department of Alternative medicine, University of Yamanashi, Yamanashi, Japan
Aim: The dynamics of HIV-1 in the peripheral blood from LTNP to AIDS is unknown. We investigated it with three methods, trying to evaluate the relationship of HIV-1 viral replication with disease progression. Methods: In this study a cohort of 64 Japanese hemophiliacs with HIV-1 infection were divided into 6 groups. 15
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10720)
Eremin VF, Gasich EL, Blashkevich NV, Barisenko ZI;;;; Research Institute for Epidemiology & Microbiology, Minsk, Belarus
To study hepatitis B , C spreading among young HIV infected IDUs in Belarus . Methods: EIA on HBsAg, anti-HCV, HIV Ag/Ab, Western blot, PCR, RT-PCR, epidemiologycal, statistical. Results: In the beginning of January 2004 cumulative number of HIV-infected patients has reached 5485 (713 new HIV cas
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10724)
Sallet J, Nqini N, Olaosebikan AA;;;; Management Sciences for Health, Boston, United States
The national HIV prevalence among antenatal clinic attendees in South Africa has shown an increase from 0.75% in 1990 to 24.8% in 2001 (Eastern Cape - 21.7 in 2001). To address this burden the PMTCT programme was piloted while at the same time addressing operational challenges inherent with introduction of anti
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10728)
Hancart Petitet P;;;; Laboratoire d'Ecologie Humaine et d' Anthropologie, Aix en Provence, France
In some part of India , women of remote rural areas still deliver at home with Traditional Birth Attendant. PMTCT programs are available only in a few health care services. Women delivering at home should also benefit of preventive measures regarding HIV transmission. Prevention should then be adapted to lo
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10732)
Awori Oketch M, Moss V, Sims R, Eriki M, Pearson N;;;; Mildmay Internationa, Jajja's Home, Kampala, Uganda
Issue : Palliative care is effective in children living with HIV/AIDS but unavailable in many resource limited settings (RLS). Description : This paper describes the observed benefits of palliative care for children with AIDS in a RLS. Jajja s Home is a day care centre for children living with AIDS; a model project dev
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10736)
De Leon M, Gimenez V, Gutierrez S, Gutierrez G, Cunetti L, Quian J;;;; Centro de Referencia Nacional Materno-Infantil HIV-SIDA/Hospital Pereira Rossell / Universidad de la Republica, Montevideo, Uruguay
Nutritional status is frequently affected in HIV-infected children, particularly the height/age ratio but there are today only a limited number of studies defining growth parameters and nutritional status for HIV children under antiretroviral therapy. To evaluate the effect of antiretroviral therapy (ARV-T)
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10740)
Hancart Petitet P;;;; Laboratoire d'Ecologie Humaine et d' Anthropologie, Aix en Provence, France
In Southern India , HIV MTCT programs have been started in some governmental hospitals and by some NGOs but it exist neither in private clinics nor in rural areas. In such context, the distance that separates HIV MTCT recommendations of International Health Organizations from the actual delivery practices may be viewed
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10744)
Garcia EG, Delbon FD;;;; UNIFESP, Sao Paulo, Brazil
According to the Sao Paulo Health Secretariat, HIV rates among youth who use crack-cocaine are rising. Usually, to maintain their drug using habits, youth are thieves and/or engaged in commercial sex. 56% of youth engaged in commercial sex never use condoms, and 46% engage in homosexual relationships. According
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10748)
Del Bianco R, Dantas S, Seabra JN, Kenj G, Zambone G, Bismarck G, Degni N, Flores O;;;; Hospital Emilio Ribas, Sao Paulo, Brazil
One of the greatest achievements in the prevention of HIV vertical transmission in the last ten years was antiretroviral therapy. The study investigated HIV counseling and the women s acceptance to perform the HIV rapid test, the use of HIV tests in the antenatal and labor periods, and the prevalence of HIV in pregnant
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10752)
Zeitlin GA, Handel JL, Greene JB;;;; Physician, New York, NY, United States
HAART efficacy is determined by quantitative plasma HIV-1 RNA. In a large HIV practice the observed rate of virologic failure (>400 cpml) fell dramatically when PPT were replaced by EDTAT for plasma collection. This study sought to compare the consistency of PCR results between these two collection methods.
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10756)
Bustos R, Collins J, Salazar R;;;; HIV / AIDS Unit, Psychology Branch. G. Almenara Hospital, Lima, Peru
Most studies on personality of HIV-infected patients have been partial evaluations. We aimed to determine the frequency and types of personality disorders in HIV - infected patients. Methods: Descriptive study of all HIV-infected patients evaluated between September 1999 and February 2000 at our psychology
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10760)
Branch SL, Broome H, Abayomi A;;;; Ladymeade reference Unit Laboratory, St Michael, Barbados
Normal lymphocyte subset ranges have been established for Caucasian populations, and have formed the basis of cut off points on which clinical management of HIV and AIDS are made. The Caribbean heritage is predominantly African and there is a scarcity of published ranges for this racial group. As 93% of the
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10764)
Chokephaibulkit K, Vanprapar N, Pongsamart W, Plipat N, Sutthent R;;;; Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
An appropriate treatment strategy for HIV-infected infants in resource-limited settings, where HAART is generally not affordable, is still unclear. Initiation with dual NRTI may be an appropriate option for those with less advanced disease. This study aimed to evaluate feasibility, duration of efficacy, and
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10768)
Collins J, Bustos R, Salazar R;;;; HIV / AIDS Unit, Psychology Branch. G. Almenara Hospital, Lima, Peru
There is little information about the potential role of personality disorders of HIV-infected patients on antiretroviral therapy failure. We aimed to determine the association among personality disorders of HIV-infected patients and HAART failure. Methods: Cross sectional study of a consecutive sample of HI
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10772)
Torres R, Cervero M, Jusdado J, Del Alamo M, Solis J;;;; H. Severo Ochoa, Madrid, Spain
Treatment interruptions is an strategy in the management of HIV-infected patients. A predictive model of factors associated with failure TI, could be interesting to support this practice. Methods: We conducted in Spain a follow-up study on 44 patients. We made a multivariate regression analysis to examine p
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10776)
Collins J, Bustos R, Salazar R;;;; HIV / AIDS Unit, Clinical Branch. G. Almenara Hospital, Lima, Peru
The potential role of personality disorders of HIV-infected patients in relation to risk of death has been little studied. We aimed to determine the association among personality disorders of HIV-infected patients and risk of death. Methods: Retrospective cohort of a consecutive sample of HIV-infected patie
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10780)
Mhuriyengwe L, Dube N, Wilson D, Muyambo R, Taudzayi T;;;; Institution-Project Support Group, Harare, Zimbabwe
The study sought to ascertain the use of peer education in PPT compliance. Methods: The study was conducted among female sex workers working in seven sites in Zimbabwe . Women were defined as sex workers if they reported accepting money or gifts in exchange for sex. At enrolment, 380 women consented to part
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10784)
Collins JA, Vizcardo R, Rodriguez L, Vega J, Sotelo C, Gutierrez L;;;; Department of Internal Medicine, Division of HIV / AIDS. G. Almenara Hospital, Lima, Peru
The HIV-related PCL is an entity little described in less developed regions. We aimed to determine the imaging features and the rhythm of growth of HIV-related PCL. Methods: Consecutive series of patient with evidence of HIV-related PCL. A radiologist revised the previous Computed Tomography (CT) or Magneti
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10788)
Jupimai T, Wicharuk S, Ananworanich J, Siangphoe U, Apateerapong W, Mekmullica J, Sosothikul D, Chomchey N, Koekkoek S, Eggermont L, Cheunyam T, Phanuphak P, Pancharoen C;;;; The HIV Netherlands Australia Thailand Research Collaboration (HIV-NAT), The Thai Red Cross AIDS Research Center (TRCARC), Bangkok, Thailand
: We hypothesize that HIV-infected children have more problems than children with other chronic diseases and normal children. Methods: : A cross-sectional study conducted between Apr-Nov 2003 involving caregivers of 3 groups of children ages 6-16 yrs: Gr 1: HIV-infected. Gr 2: Heme/Onc disease receiving blo
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10792)
Singh B, Kumar A;;;; University of West Indies & Queen Elizabeth Hospital, St. Michael, Barbados
In Barbados , voluntary counseling and testing (VCT) for HIV was commenced in early nineties and uptake of this service has been over ninety percent. One of the benefits of VCT, besides use of antiretroviral prophylaxis for prevention of perinatal transmission is to detect HIV infected women early in the co
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10796)
Vanprapar N, Sutthent R, Chokephaibulkit K, Phongsamart W, Chearskul P, Plipat N;;;; Pediatric Infectious Diseases unit, Department of Pediatrics, Siriraj Hospital Mahidol University, Bangkok, Thailand
Decisions to start ART and therapeutic responses are based on the amount of viral load. Ampiclor HIV-1 monitor is a gold standard test, but it is labor intensive, time consuming and expensive. The HIV-1 p24 antigen is not an expensive test, but is not sensitive enough for clinical application. The modified
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10800)
Paungtubtim W, Thaisri H, Vongsheree S, Sawanpanyalert P, Rojanawiwat A, Sri-ngam P, Jaisue R, Chadbanchachai C, Kongpromsook W, Lerwitworapong J;;;; National Institute of Health, Department of Medical Science, Ministry of Public Health, Nonthaburee, Thailand
High rates of hepatitis C virus (HCV) infection among inmates have been reported worldwide. However, less information on HCV infection and risk factors among inmates in Thailand is available. Method: A prospective cohort of 689 male inmates in a Bangkok central prison was studied during 2001-2
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10804)
Shang H, Han XX, Zhang M, Wang YN, Zhang ZN, Jiang YJ, Liu J;;;; AIDS Research Center, the First Affiliated Hospital, China Medical University, Shenyang Liaoning, China
The genetic diversity of HIV- pol gene and PI and RT resistance-associated mutations were studied in 54 seropositive treatment-naive residents of the northeast of China to examine the prevalence of drug resistance mutations in China. Methods: HIV-1 partial pol genes in infected plasma samples were amplified
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10808)
Massawe A, Karlsson K, Kilewo C, Swai A, Lyamuya E, Mhalu F, Biberfeld G;;;; 1Muhimbili University College for Health Sciences, Dar es Salaam, Tanzania
Background : The objective of this study was to analyse mortality in a cohort of children at the Dar es Salaam site of the UNAIDS multicentre Petra trial (a mother-to-child HIV-1 transmission intervention study using antiretroviral therapy). Antiretroviral treatment was not available in this setting apart from the shor
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10812)
Caplinskas S, Caplinskiene I, Nagys Z;;;; Lithuanian AIDS Centre, Vilnius, Lithuania
Background. Problem of premature sexual practices becomes more serious in Lithuania . Condom import doubled in the last 8 years (1995-2002). Condom issues are practically not included into school curricula because of objections of Ministry of Education and Science. Knowledge on safer sex is mainly available in the non-
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10816)
van der Ven A, Bleeker-Rovers CP, Zomer B, Koopmans P, de Geus-Oei LF, Oyen WJ;;;; Department of Internal Medicine, University Medical Center Nijmegen, Nijmegen, Netherlands
Lipodystrophy, an important complication of HAART, is a clinical diagnosis with early features often presenting 12-16 months after initiation of therapy. One hypothesis is that the pro-inflammatory response to HAART causes subcutaneous inflammation resulting in lipodystrophy. Since F-18-fluorodeoxyglucose (
To explore personal and system-related barriers to adherence to anti-retroviral therapy amongst patients at Lighthouse Clinic. The Lighthouse, a comphrehensive HIV/AIDS non-government service provider which implements the Government of Malawi provision of ART at a cost of drugs to patients in Lilongwe. Meth
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10824)
Gruzdev BM, Kravchenko AV, Potekaev NN;;;; Moscow city AIDS Center, Moscow, 105275, Russian Federation
KS is the most common tumor in HIV-infected pts in Russia . The objective of this study was assessment of frequency of registration of KS in pts with HIV. Materials and methods: Pts with combined HIV-infection and KS, hospitalized in Infectious Clinical Hospital N2 of Moscow, have been examined over 16-yr p
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10828)
Alyaeva MD, Ermak TN, Kholodilova MA;;;; Russian Federal AIDS Centre, Moscow, Russian Federation
Cerebral toxoplasmosis -one from leading opportunistic infections. The purpose of our work was to study clinical data and toxoplasmosis status in the structure of opportunistic diseases in AIDS patients. Methods: Clinical analysis of all cases of toxoplasmosis among AIDS patients during last 5 year Epidemic
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10832)
Rjaplov Jury RJ;;;; Charity Foundation 'Anti-AIDS', Lugansk, Ukraine
HIV./A1DS/STO Prevention Among Intravenous Drug Users in LuganskAccording to the latest census there are 525 thousand people living in the city of Lugansk. As of 01.02. 2003., 5875 people who use psychotropic substances for non-medical purposes were registered at the regional narcological dispensary. According t
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10836)
Giovannini M, Salvini F, Zuccotti GV, Cucchi C, Gemmellaro L, Testolin C, Riva E;;;; Department of Paediatrics- San Paolo Hospital- University of Milan, Milan, Italy
In HIV infected children, CD45+CD4+ T lymphocytes reconstitution has been related to efficient thymopoiesis. Because human thymus undergoes spontaneous involution at a relatively young age, institution of antiretroviral therapy early in the course of infection has been recommended. Methods: in 12 HIV vertic
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10840)
Staszewski S, Dauer B, Carlebach A, Moesch M, Gute P, Klauke S, Stuermer M;;;; JW Goethe-Universitat, Frankfurt, Germany
week data from the initial cohort of the LOPSAQ study was previously reported. This is an extended analysis of the full cohort over 48 weeks. Methods: Cohort study of 163 heavily pre-treated patients who were experiencing treatment failure with an reverse transcriptase inhibitor (RTI)-containing regimen due
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10844)
Mian M, Kozlowska J, Hryniewicz H, Mikula T, Cianciara J;;;; Warsaw Medical University, Warsaw, Poland
To determine the liver status and its effect on the course of HIV infection we undertook an observation of 118 AIDS patients. Methods: A total number of 118 AIDS patients hospitalized in our department during the years 1999-2003 were analyzed (male 91, female 27, mean age 38,1 +/- 9,8, age range 22-70 years
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10848)
Marczynska MM, Palczewska I, Szilagyi-Pagowska I, Szczepanska-Putz M;;;; Department of Growth and Development of Chlidren and Youth, Institute of Mother and Child, Warsaw, Poland
Background. HIV infection influences somatic development. The introducing of HAART demonstrated clinical, immunological and survival benefits, but also problems with metabolic abnormalities and/or lipodystrophy occurred. The aim was to present anthropometric measurements and to evaluate somatic development of HIV infec
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10852)
Orani A, Perini P, Valota M, Castaldo G, Nigro M, Fossati M;;;; Ospedale 'A. Monxoni' - UO Malattie Infettive e tropicali, Lecco, Italy
The main aim of this study is to evaluate the efficacy and tolerability of combination therapy in HIV/HCV coinfected patients, especially those treated with HAART, using the stopping rule testing at 12 week (early virological response: HCV-RNA neg or drop >2 logs ); secondary objectives consider the opportunity
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10856)
Torpey K, Asare R, Nyarko C, Agyeman P, Yanney J, Drah B, Essah K;;;; Family Health International, Accra, Ghana
The use of antiretroviral therapy is associated with a decline in morbidity and mortality and improvement in the quality of life. Antiretroviral drugs is, however, also associated with side effects and toxicity. Anaemia is one of the important side effects of Zidovudine. The W. H. O recommends the use of tw
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10860)
Portu J, Aldamiz-etxeberria M, Izagirre M, Tarabini P, Apraiz L, Pinedo A;;;; Hospital Txagorritxu, Vitoria-Gasteiz, Spain
Background : Pneumonia caused by Legionella pneumophila, a significant pathology in inmunosuppressed, has hardly been described in HIV patients. We will describe the pneumonia cases in a sample infected by HIV in a latent tuberculous infection treatment programme. Methods : The Legionella cases were diagnosed by: radio
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10864)
Durojaiye E, Awofodu B, Eziefule B, Atuma E;;;; Center for the Right to Health, Lagos, Nigeria
Many people living with HIV/AIDS in Nigeria are denied access to treatment mainly due to unavailability of drugs and discriminatory attitudes of health care workers. In addition non-respect for privacy and breach of confidentiality are rife in the health care sector. This situation often discourages PLWHA to see
Proviral HIV-1 DNA persists in peripheral blood mononuclear cells (PBMCs) and lymphoid tissue even in patients under HAART and is one of the major obstacles to the total eradication of the virus, even if treatment is initiated at an early stage. Monitoring of HIV-1 proviral DNA can be a very important tool
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10872)
Torpey K, Ampofo W, Nyarko C, Asare R, Antwi P, Essah K;;;; Family Health International, Accra, Ghana
The availability of antiretroviral drugs has converted HIV/AIDS from a terminal to a chronic disease. Antiretroviral drugs have been available in the past five years but the cost has been very prohibitive and unaffordable. Family Health International START program in partnership with the National AIDS Contr
Despite the iNtensive Condom Social Marketing in Katsina [ a core Muslim, Northern state of Nigeria , where the sharia legal system is enforced], as a barrier preventive method against HIV/AIDS, theere has been a very poor compliance/user rate, despite the incidence of the disease in the state. This study t
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10884)
Costa JA, Lima M, Figueiredo WS, Schraiber LB;;;; Specialized clinic of STD/AIDS Santana - Health Departament - Sao Paulo City council
Work aimed towards PLWA has brought in barriers in professional fields, among which is the difficulty relating to the use of drugs. The objective of this study was to understand how the notions and values among professionals has influenced their care of PLWA that are drug user (DU). Methods: This was a qual
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10888)
Bulla AK, Makandawire NE, Chilongozi DA, Martinson FE, Chasela CS, Manyera R, Salima CF, Wemba CS, Kamanga SE, Kumbanga FF, Dzinyemba WE, Joaki GR, Valentine M, Hoffman IF;;;; UNC Project, Lilongwe Central Hospital, Lilongwe, Malawi
Recruitment of subjects is one step to success in conducting HIV clinical trials in developing countries. Misconceptions about HIV research are common. Methods: A Phase III, randomized, placebo-controlled trial (HIVNET 024) to reduce chorioamnionitis-associated mother-to-child transmission of HIV was conduc
Int Conf AIDS 2004 Jul 11-16; 15:(abstract no. B10892)
Silva NE, Oliveira LA, Franca-Junior I;;;; Specialized clinic of STD/AIDS Santana - Health Departament - Sao Paulo City council
Even considering the importance of prophylaxis against vertical HIV transmission in countries like Brazil , the notion of epidemiological risk does not have the same significance for healthcare prof
