With the prolonged demise of HIV eradication hypotheses and the growing appreciation of the various unpleasant realities of lifelong HAART, the issue of the optimal time to initiate treatment with antiretroviral therapy in chronically HIV-infected individuals is enjoying something of a renaissance.
When it comes to bacterial and fungal infections, wherever there is treatment, we don't accept a little bit of positive blood cultures. We happily accept that with HIV. Where's the difference here?