Your Search for AACTG or Adult AIDS Clinical Trials Group matched 167 Documents (Page 1 of 6).
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Abstract: MMAS may be superior to AACTG, due to less internal attrition. Association between MMAS and viral load was found, but not for AACTG, possibly due to lack of power. AACTG may be too complicated for this unselected HIV-infected population, and the item wording may have encouraged social desirability explaining the higher ...
http://www.aegis.org/conferences/hiv-glasgow/2006/p174.html
File Name: p174.html, Size: 6KB, Last Modified: Sunday, November 12, 2006 at 8:12:04 PM
Abstract: aids, hiv, AIDS, HIV, hiv/aids, gmhc, GMHC, Gay Men's Health Crisis, Treatment Issues, ti, TI, treatment, strategies. Important note: Information in this article was accurate in May 2001. The state of the art may have changed since the publication date.EDITORIAL: It's Time for New Leadership at the AACTG. ...
http://www.aegis.org/pubs/gmhc/2001/gm150506.html
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Abstract: PITTSBURGH, Jan. 18 /PRNewswire/ -- The University of Pittsburgh has been awarded a major AIDS research grant to become part of the Adult AIDS Clinical Trials Group (AACTG), the world s largest clinical trials network, which is sponsored by the National Institutes of Health s National Institute of Allergy and Infectiou ...
http://www.aegis.org/news/pr/2000/pr000113.html
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Abstract: Introduction: Inadequate adherence is the most important factor predicting failure to HAART in HIV-infected subjects. With the recently implemented government-funded antiretroviral program in Mexico , use of HAART is now widespread in this country, however the prevalence of non-adherence and the optimal instruments hav ...
http://www.aegis.org/conferences/iac/2004/b12476.html
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Abstract: This paper describes the AACTG Adherence Instruments, which are comprised of two self-report questionnaires for use in clinical trials conducted by the Adult AIDS Clinical Trials Group (AACTG). The questionnaires were administered to 75 patients at ten AACTG sites in the USA. All patients were taking combination antir ...
http://www.aegis.org/aidsline/2000/nov/a00b0936.html
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Abstract: Although U.S. government clinical trials for AIDS were once at the forefront of HIV treatment research, during the past few years pharmaceutical sponsors have taken over the job of conducting the most important studies of new anti-HIV medications. ...
http://www.aegis.org/pubs/gmhc/2001/gm150501.html
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Abstract: Dyslipidaemia is a common problem affecting HIV-infected patients receiving antiretroviral therapy. Since publication of preliminary guidelines in 2000, numerous studies have addressed the risk of cardiovascular disease, the mechanisms of dyslipidaemia, drug interactions, and the treatment of lipid disorders in HIV-inf ...
http://www.aegis.org/pubs/i-base/2003/ib030408-18.html
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Abstract: The AACTG NeuroScreen is a brief, simple and low-cost global screening tool that provides acceptable diagnostic efficiency in HIV neurological disease. Serial NeuroScreen assessments in A5001 and A362 will permit estimation of the prevalence and course of neurocognitive impairment and DSPN in over 3000 individuals. Bec ...
http://www.aegis.org/conferences/croi/2004/493.html
File Name: 493.html, Size: 8KB, Last Modified: Sunday, February 08, 2004 at 8:12:04 PM
Abstract: Genetic variants may predict virologic failure and/or emergence of drug-resistant HIV. "Efavirenz and nelfinavir are metabolized by cytochrome P-450 (CYP) 2B6 and CYP2C19, respectively, with some involvement by CYP3A. Nelfinavir is a substrate for P-glycoprotein, which is encoded by MDR1. The present study examined ass ...
http://www.aegis.org/pubs/aidswkly/2006/aw060104.html
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Abstract: <p><b>BACKGROUND:</b> Defining immunologic, virologic, and host factors that influence response to Antiretroviral Therapy (ART), and their impact on long-term outcomes is key to individualizing therapy for HIV + pts. </p> <p><b>METHODS:</b> We analyzed baseline (BL) factors associated with ART response in HIV + , ART- ...
http://www.aegis.org/conferences/croi/2003/572.html
File Name: 572.html, Size: 7KB, Last Modified: Monday, February 10, 2003 at 8:12:04 PM
Abstract: CARLSBAD, Calif., and LA JOLLA, Calif., May 10 /PRNewswire/ -- The Immune Response Corporation (Nasdaq: IMNR) and Agouron Pharmaceuticals, Inc. today announced that a pivotal trial has been initiated to evaluate the safety and efficacy of the investigational product REMUNE(TM) (HIV-1 Immunogen) in increasing durability ...
http://www.aegis.org/news/pr/2000/pr000511.html
File Name: pr000511.html, Size: 12KB, Last Modified: Wednesday, May 10, 2000 at 3:00:00 PM
Abstract: Expected elevations of TC and TGC due to pregnancy were observed in both groups and declined after delivery. Fasting TC and TGC were higher in protease inhibitor treated patients in pregnancy. Increased LPD levels did not affect pregnancy outcome, but long term significance is unclear. LAC levels, even the few that wer ...
http://www.aegis.org/conferences/lipo/2006/64.html
File Name: 64.html, Size: 8KB, Last Modified: Monday, September 25, 2006 at 6:29:23 AM
Abstract: These results show that with a large enough dataset and adequate distribution of resistance levels, the performance of interpretation systems for identifying abacavir and ddI resistance can be evaluated and that several of these systems performed well. ...
http://www.aegis.org/conferences/hivdrw/2006/84.html
File Name: 84.html, Size: 6KB, Last Modified: Wednesday, June 14, 2006 at 6:29:23 AM
Abstract: Multilocus interactions involving genes important for T-cell expansion and survival may predict CD4 increases during ART. Further studies are warranted to validate these associations and define underlying mechanisms. ...
http://www.aegis.org/conferences/croi/2006/443.html
File Name: 443.html, Size: 7KB, Last Modified: Sunday, February 05, 2006 at 8:12:04 PM
Abstract: DAPD and MMF were safe and well tolerated. DAPD monotherapy had modest antiretroviral activity (–0.35 log10) in heavily pre-treated subjects with extensive NRTI resistance. In contrast to synergy observed in vitro, DAPD activity over 2 weeks was not increased by MMF (500 mg twice daily) in this study. Assays of DAPD an ...
http://www.aegis.org/conferences/croi/2006/517.html
File Name: 517.html, Size: 8KB, Last Modified: Sunday, February 05, 2006 at 8:12:04 PM
Abstract: These results raise the question of external validation of existing interpretation systems and emphasize the need for collaborative work to improve existing systems both by increasing the sample size and by developing innovative statistical approaches. ...
http://www.aegis.org/conferences/hivdrw/2005/9.html
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Abstract: Mitochondrial haplogroup T was more frequent in Caucasians who developed subjective peripheral neuropathy while on ddI/d4T during Study 384. The polymorphism that defines this haplogroup is located in the ND5 region of the mitochondrial gene encoding Complex I respiratory transport chain subunits and may point to varia ...
http://www.aegis.org/conferences/croi/2005/43.html
File Name: 43.html, Size: 8KB, Last Modified: Tuesday, February 22, 2005 at 8:12:04 PM
Abstract: AEGiS, 12th Conference on Retroviruses and Opportunistic Infections, San Francisco, HIV, AIDS,. 12th Conference on Retroviruses and Opportunistic Infections Boston, Massachusetts - February 22-25, 2005FACTORS ASSOCIATED WITH TIME TO CD4 COUNT < 350/mm3 AFTER A TREATMENT INTERRUPTION FOLLOWING EFFECTI ...
http://www.aegis.org/conferences/croi/2005/582.html
File Name: 582.html, Size: 8KB, Last Modified: Tuesday, February 22, 2005 at 8:12:04 PM
Abstract: Plasma F2-IsoP levels were unexpectedly high at baseline in cryopreserved specimens from these study subjects compared to levels from a previous study that included HIV-infected adults not receiving ART. This may reflect ex vivo auto-oxidation of some plasma specimens. Although F2-IsoP increases tended to be somewhat g ...
http://www.aegis.org/conferences/croi/2005/399.html
File Name: 399.html, Size: 9KB, Last Modified: Tuesday, February 22, 2005 at 8:12:04 PM
Abstract: Subjects with a variant T allele at CYP2B6 position 516 may be at increased risk for developing NNRTI-resistant HIV-1 when simultaneously stopping all drugs in EFV-containing regimens, although variability within genotypes is considerable. Risk is greatest in T/T homozygotes with prolonged medication discontinuation. T ...
http://www.aegis.org/conferences/croi/2005/651.html
File Name: 651.html, Size: 8KB, Last Modified: Tuesday, February 22, 2005 at 8:12:04 PM
Abstract: The comparison between double and single PI groups was limited by early termination of enrollment and the resulting small sample size. RNA and CD4+ cell responses did not differ significantly between groups in the ITT analyses and trends favored the double PI group in the AT analyses, although this should be interpret ...
http://www.aegis.org/conferences/croi/2005/577.html
File Name: 577.html, Size: 9KB, Last Modified: Tuesday, February 22, 2005 at 8:12:04 PM
Abstract: Treatment with EFV+2 NRTI led to lower rates of regimen failure than treatment with LPV/r+EFV, due to decreased toxicity and a trend toward reduced virologic failure. ...
http://www.aegis.org/conferences/croi/2005/162.html
File Name: 162.html, Size: 8KB, Last Modified: Tuesday, February 22, 2005 at 8:12:04 PM
Abstract: BACKGROUND: As HIV-related therapies and supportive services are provided in resource limited settings, it is crucial to have reliable evaluation methods. Aside from mortality, little data is collected on the human impact of HIV. Patient questionnaires can be used to assess therapies, care and services, and policies. W ...
http://www.aegis.org/conferences/iac/2004/e11602.html
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Abstract: Overall, the PI NFV and the NNRTI EFV appear to have comparable effects on fasting lipids, with a better total:HDL-C ratio with EFV. Lipids tended to be slightly more favorable with ZDV+3TC than ddI+d4T. HDL-C changes correlated with entry HIV disease status. Insulin resistance worsened in the group as a whole, but did ...
http://www.aegis.org/conferences/croi/2004/74.html
File Name: 74.html, Size: 9KB, Last Modified: Sunday, February 08, 2004 at 8:12:04 PM
Abstract: <p><b>BACKGROUND:</b> Published reports of the prevalence of asymptomatic hyperlactatemia among HIV-infected individuals have ranged from 4%-36%. The significance of these elevations in lactate in the absence of symptoms remains uncertain. In addition, the variability in the reported AH prevalence may reflect cohort di ...
http://www.aegis.org/conferences/croi/2003/761.html
File Name: 761.html, Size: 7KB, Last Modified: Monday, February 10, 2003 at 8:12:04 PM
Abstract: <p><b>BACKGROUND:</b> To inform adherence interventions with HIV+ mothers, we examined the association between mental health, substance abuse, and family factors, and medical treatment adherence. </p> <p><b>METHODS:</b> Self-report data were collected by individual interviews in a longitudinal study of psychosocial ...
http://www.aegis.org/conferences/iac/2002/thpee7809.html
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Abstract: John Barrow, M.D.. Dr. John Barrow received his doctorate degree from the University of South Florida. He has many years experience in the field of Pathology, the scientific study of the nature of disease and its causes, processes, development and consequences. He also earned a Bachelor of Science degree in Zoology an ...
http://www.aegis.org/askdoc/barrow.html
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Abstract: John Barrows, M.D.. Dr. John Barrows received his doctorate degree from the University of South Florida. He has many years experience in the field of Pathology, the scientific study of the nature of disease and its causes, processes, development and consequences. He also earned a Bachelor of Science degree in Zoology a ...
http://www.aegis.org/askdoc/barrows.html
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Abstract: Use of human immunodeficiency virus (HIV) drug-resistance testing in therapeutic decision making may be aided by understanding the relationship between results of genotypic and drug-susceptibility phenotypic assays. We investigated this relationship by applying 3 different statistical methods-cluster analysis, recursi ...
http://www.aegis.org/aidsline/2000/nov/a00b1056.html
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Abstract: OBJECTIVE: To determine the efficacy and safety of amphotericin B oral suspension (ABOS) for the treatment of fluconazole refractory oral candidiasis in persons with HIV infection. DESIGN AND SETTING: A prospective, multicenter, open label trial at 25 study centers within the AIDS Clinical Trials Group. PATIENTS AND M ...
http://www.aegis.org/aidsline/2000/oct/a00a0378.html
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