Your Search for AIDS dementia complex matched 1000 Documents (Page 1 of 34).
You may want to refine your search. Results Indexed by relevance.
Abstract: It has been hypothesized that didanosine has a low efficacy in the prevention and treatment of patients with the dementia complex of acquired immunodeficiency syndrome (AIDS) because ... the drug has not been detected in the cerebrospinal fluid. We investigated didanosine concentra ...
http://www.aegis.org/aidsline/1996/jun/m9660193.html
File Name: m9660193.html, Size: 9KB, Last Modified: Thursday, January 08, 2009 at 1:03:30 AM
Abstract: A common complication of acquired immunodeficiency syndrome (AIDS) is being increasingly recognized. Known as AIDS dementia complex, the disorder is characterized by global impairment of intellectual and cognitive functions, personality and behavioral disturbances, and motor dysfun ...
http://www.aegis.org/aidsline/1989/oct/m89a0230.html
File Name: m89a0230.html, Size: 8KB, Last Modified: Wednesday, January 07, 2009 at 5:29:48 AM
Abstract: The acquired immunodeficiency syndrome (AIDS) dementia complex is a frequent and devastating complication of infection with human immunodeficiency virus-type 1 (HIV-1). Features of the AIDS dementia complex include decreased memory, the inability to concentrate, apathy, and psychom ...
http://www.aegis.org/aidsline/1989/nov/m89b0069.html
File Name: m89b0069.html, Size: 9KB, Last Modified: Wednesday, January 07, 2009 at 5:28:35 AM
Abstract: Brain glucose metabolism was evaluated in four patients with acquired immunodeficiency syndrome (AIDS) dementia complex using [18F]fluorodeoxyglucose (FDG) and positron emission tomography (PET) scans at the beginning of therapy with 3 -azido-2 ,3 -dideoxythymidine ( ...
http://www.aegis.org/aidsline/1989/aug/m8980332.html
File Name: m8980332.html, Size: 10KB, Last Modified: Wednesday, January 07, 2009 at 5:22:51 AM
Abstract: Single photon emission computed tomography (SPECT) studies were performed in AIDS dementia complex using IMP in 12 patients (and HM-PAO in four of these same patients). In all patients, SPECT revealed either multiple or focal uptake defects, the latter corresponding with focal sign ...
http://www.aegis.org/aidsline/1988/nov/m88b0311.html
File Name: m88b0311.html, Size: 8KB, Last Modified: Wednesday, January 07, 2009 at 5:18:47 AM
Abstract: Infection with human immunodeficiency virus type 1 (HIV-1) is frequently complicated in its late stages by the AIDS dementia complex, a neurological syndrome characterized by abnormalities in cognition, motor performance, and behavior. This dementia is due partially or wholly to a ...
http://www.aegis.org/aidsline/1988/may/m8850189.html
File Name: m8850189.html, Size: 10KB, Last Modified: Wednesday, January 07, 2009 at 5:18:10 AM
Abstract: BACKGROUND: HIV-1 replication in the brain results in AIDS dementia complex in about 30% of AIDS patients. The mechanisms that lead to neuropathogenesis are unclear. Also it is not known whether neurotropic or neurovirulent HIV-1 variants are involved. Others reported HIV-1 isolates with enhanced tropism and fusigenici ...
http://www.aegis.org/conferences/croi/2004/460.html
File Name: 460.html, Size: 7KB, Last Modified: Sunday, February 08, 2004 at 8:12:04 PM
Abstract: AIDS Dementia Complex ( ADC ) is now also referred to as HIV-1-associated cognitive/motor complex and in its more severe form involving cognitive impairment as HIV-1-associated dementia . It was recognized early in the AIDS epidemic and there remains to be controversy in its nomenclature and formal diagnosis. ...
http://www.aegis.org/pubs/books/1997/bk970617.html
File Name: bk970617.html, Size: 8KB, Last Modified: Monday, April 01, 2002 at 11:23:30 PM
Abstract: This is the first issue of a new journal that will include articles on the practical clinical issues related to characterization, diagnosis and treatment of nervous system complications of HIV-1 infection as well as considerations of more basic issues related to the neurobiology, virology, immunology and pathogenesis o ...
http://www.aegis.org/pubs/books/1995/bk95c447.html
File Name: bk95c447.html, Size: 8KB, Last Modified: Monday, April 01, 2002 at 11:23:14 PM
Abstract: BACKGROUND: Recently, the incidence of AIDS dementia complex (ADC) has been found to have halved as a consequence of the introduction of highly active antiretroviral therapy (HAART) but it is unknown whether this can be maintained with long-term HAART. Moreover, it is not clear what factors are important in ADC develop ...
http://www.aegis.org/conferences/croi/2002/61.html
File Name: 61.html, Size: 7KB, Last Modified: Sunday, February 24, 2002 at 8:12:04 PM
Abstract: BACKGROUND AND PURPOSE: Recent studies have reported the clinical improvement in patients with AIDS treated with a combination of antiretroviral regimens. The purpose of our study was to describe the effects of highly active antiretroviral therapy on MR images in patients with HIV encephalopathy and to compare the cli ...
http://www.aegis.org/aidsline/2000/sep/a0091195.html
File Name: a0091195.html, Size: 9KB, Last Modified: Thursday, September 28, 2000 at 8:12:04 PM
Abstract: <p><b>ISSUES:</b> The advent of combination therapy has led to an increasing number of clients with an amalgam of complex issues including AIDS Dementia Complex (ADC), psychiatric conditions, substance abuse issues and psychosocial issues. These clients pose significant challenges for HIV services and service provide ...
http://www.aegis.org/conferences/iac/2000/weped4514.html
File Name: weped4514.html, Size: 7KB, Last Modified: Sunday, July 09, 2000 at 8:12:04 PM
Abstract: AIDS dementia complex (ADC) is characterized by immune activation of glial cells, resulting in altered production of molecules with toxic or neuroprotective features. We indeed show an increased IL-1B expression in brain tissue of 7 clinically demented AIDS patients compared to 6 n ...
http://www.aegis.org/aidsline/2000/may/a0050415.html
File Name: a0050415.html, Size: 9KB, Last Modified: Sunday, May 28, 2000 at 8:12:04 PM
Abstract: The chemokine receptor CCR5 and to a lesser extent CCR2b and CCR3 have been shown to serve as coreceptors for HIV-1 entry into macrophages. Individuals that are homozygous for a defective CCR5 allele (DeltaCCR5) are highly, but not fully, resistant to infection with HIV-1. Here, we want to emphasize the importance of ...
http://www.aegis.org/aidsline/2000/mar/a0030533.html
File Name: a0030533.html, Size: 9KB, Last Modified: Tuesday, March 28, 2000 at 8:12:04 PM
Abstract: AIDS dementia complex (ADC) is characterized by immune activation of glial cells, resulting in altered production of molecules with toxic or neuroprotective features. We indeed show an increased IL-1beta expression in brain tissue of 7 clinically demented AIDS patients compared 6 n ...
http://www.aegis.org/aidsline/2000/jan/a0010112.html
File Name: a0010112.html, Size: 10KB, Last Modified: Friday, January 28, 2000 at 8:12:04 PM
Abstract: Neurotoxic factors released from macrophages and microglia are believed to play a central role in mediating neuronal damage in the AIDS dementia complex (ADC). A toxin involved in ADC pathogenesis should ideally fulfil a number of criteria. These criteria are production by macropha ...
http://www.aegis.org/aidsline/2000/jan/a0010067.html
File Name: a0010067.html, Size: 9KB, Last Modified: Friday, January 28, 2000 at 8:12:04 PM
Abstract: OBJECTIVES: To determine the protective efficacy of highly active antiretroviral therapy (HAART) against AIDS dementia complex (ADC) relative to other initial AIDS-defining illnesses (ADIs), Australian AIDS notification data over recent years were examined. METHODS: All initial ADI ...
http://www.aegis.org/aidsline/1999/nov/a99b0570.html
File Name: a99b0570.html, Size: 10KB, Last Modified: Sunday, November 28, 1999 at 8:12:04 PM
Abstract: Heterozygosity for a 32-bp deletion in the CCR5 gene (CCR5 Delta32), which encodes the coreceptor for macrophage-tropic non-syncytium-inducing (NSI) human immunodeficiency virus type 1 (HIV-1) variants, results in a lower CCR5 expression and reduced NSI HIV-1 replication. Because infection of macrophages and microglia ...
http://www.aegis.org/aidsline/1999/nov/a99b0108.html
File Name: a99b0108.html, Size: 9KB, Last Modified: Sunday, November 28, 1999 at 8:12:04 PM
Abstract: Although neurotrophic factors are currently considered as treatment for neurodegenerative diseases, little is still known about their presence in the central nervous system under pathological conditions. We investigated the expression of the neurotrophic molecules NGF, bFGF, BDNF and IGF-1 in brain tissue of patients ...
http://www.aegis.org/aidsline/1999/sep/a9990620.html
File Name: a9990620.html, Size: 10KB, Last Modified: Tuesday, September 28, 1999 at 8:12:04 PM
Abstract: Investigators reporting in the September issue of the Journal of Infectious Diseases suggest that the CCR5 delta 32 mutation may offer protection against AIDS dementia complex. According to the team, heterozygosity for CCR5 delta 32 is associated with limited cell surface expression of CCR5, reduced non- syncytium-indu ...
http://www.aegis.org/news/ads/1999/ad991380.html
File Name: ad991380.html, Size: 9KB, Last Modified: Thursday, August 19, 1999 at 3:00:00 PM
Abstract: Oxidative stress is suggested to be involved in several neurodegenerative diseases. One mechanism of oxidative damage is mediated by peroxynitrite, a neurotoxic reaction product of superoxide anion and nitric oxide. Expression of two cytokines and two key enzymes that are indicative of the presence of reactive oxygen ...
http://www.aegis.org/aidsline/1999/jul/a9970630.html
File Name: a9970630.html, Size: 10KB, Last Modified: Wednesday, July 28, 1999 at 8:12:04 PM
Abstract: Australian researchers report in the journal AIDS that highly active antiretroviral therapy (HAART) is less effective in preventing AIDS dementia complex than other AIDS-related conditions. Investigators followed patients receiving HAART from 1995 to 1997, and found that illnesses related to AIDS dementia complex rose ...
http://www.aegis.org/news/ads/1999/ad991158.html
File Name: ad991158.html, Size: 9KB, Last Modified: Wednesday, July 14, 1999 at 3:00:00 PM
Abstract: Prospective proton chemical shift imaging (CSI) of the brain was performed in 30 HIV- 1-seropositive patients and 11 healthy controls. Significant (P ...
http://www.aegis.org/aidsline/1999/jun/a9960209.html
File Name: a9960209.html, Size: 9KB, Last Modified: Monday, June 28, 1999 at 8:12:04 PM
Abstract: A number of studies have shown that HIV infection is associated with decreased olfactory ability. Additionally, it has been hypothesized that a reduced odorant identification may precede the advent of AIDS Dementia Complex (ADC). However, it is not known whether changes in olfactory ability are a manifestation of neur ...
http://www.aegis.org/aidsline/1999/mar/a9931026.html
File Name: a9931026.html, Size: 10KB, Last Modified: Sunday, March 28, 1999 at 8:12:04 PM
Abstract: OBJECTIVES: To study the biological properties and molecular architecture of HIV-1 strains implicated in AIDS dementia complex. (ADC) DESIGN: A systematic study to identify neurotropic variants of HIV-1 in the V3 region (a region important in viral tropism and neutralization) and t ...
http://www.aegis.org/aidsline/1998/dec/m98c4752.html
File Name: m98c4752.html, Size: 10KB, Last Modified: Tuesday, December 29, 1998 at 6:29:23 AM
Abstract: BACKGROUND: While standard neurological, psychiatric and neuropsychological tests provide a limited measure of viral influence in HIV, magnetic resonance spectroscopy (MRS) may provide a non-invasive biochemical measure of the metabolic alterations observed in a given region of the brain. This work seeks to assess met ...
http://www.aegis.org/aidsline/1998/dec/m98c6203.html
File Name: m98c6203.html, Size: 10KB, Last Modified: Tuesday, December 29, 1998 at 6:29:23 AM
Abstract: ISSUES: This paper describes the development, implementation and operation of an innovative community based housing project who are at risk with AIDS dementia complex. PROJECT: As a result of a crisis in care for a young man at high risk with AIDS dementia, a model of care was deve ...
http://www.aegis.org/aidsline/1998/dec/m98c1350.html
File Name: m98c1350.html, Size: 9KB, Last Modified: Tuesday, December 29, 1998 at 6:29:23 AM
Abstract: BACKGROUND: Limited treatment options currently exist for patients with AIDS dementia complex (ADC). Abacavir (ABC), a new nucleoside analogue, has been shown to have good CSF penetration. A randomised, double blin ...
http://www.aegis.org/aidsline/1998/dec/m98c3703.html
File Name: m98c3703.html, Size: 10KB, Last Modified: Tuesday, December 29, 1998 at 6:29:23 AM
Abstract: ISSUES: People diagnosed with AIDS dementia complex (ADC) are initially confronted by the term itself. Often the medical definition does not symbolically correlate with the meanings the person applies to his experiences. The fear, vulnerability and fragile sense of self forces the ...
http://www.aegis.org/aidsline/1998/dec/m98c4035.html
File Name: m98c4035.html, Size: 9KB, Last Modified: Tuesday, December 29, 1998 at 6:29:23 AM
Abstract: ...
http://www.aegis.org/aidsline/1998/aug/m9880275.html
File Name: m9880275.html, Size: 7KB, Last Modified: Saturday, August 29, 1998 at 6:29:23 AM