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Abstract: Seventy-four sequential lymph node biopsies from 30 acquired immunodeficiency syndrome (AIDS)/AIDS-related complex (ARC) patients showed temporal histologic progression from explosive follicular hyperplasia (EFH) to mixed follicular hyperplasia/involution (mixed) to follicular involution (FI) to lymphocyte depletion ( ...
http://www.aegis.org/aidsline/1989/sep/m8990677.html
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Abstract: Patients with acquired immune deficiency syndrome (AIDS) or AIDS-related complex (ARC) are subject to recurrent and severe infections due to organisms known to cause red blood cell membrane modifications. These red cell modifications include the exposure of novel carbohydrate cryptantigens that can react with naturall ...
http://www.aegis.org/aidsline/1989/sep/m8990303.html
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Abstract: STUDY OBJECTIVE: To determine alterations in serum thyroid hormone indices in patients with human immunodeficiency virus (HIV) infection. DESIGN: Prospective, single-blind study. SETTING: Large metropolitan hospital where 20% of all patients with the acquired immunodeficiency syndrome (AIDS) in Los Angeles are treated ...
http://www.aegis.org/aidsline/1989/sep/m8990058.html
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Abstract: Although the human immunodeficiency virus can induce cytopathic changes in human lymphocytes in vitro, the mechanism(s) underlying progressive lymphopenia in patients with AIDS and AIDS-related complex has not been elucidated. To investigate this issue, peripheral blood lymphocytes of AIDS and AIDS-related complex pat ...
http://www.aegis.org/aidsline/1989/sep/m8990025.html
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Abstract: The authors examined levels of psychosocial distress and well-being in 65 gay or bisexual men infected with the human immunodeficiency virus (HIV); 24 of these men had asymptomatic HIV infection, 22 had acquired immune deficiency syndrome (AIDS)-related complex, and 19 had AIDS. All of the men evidenced high levels of ...
http://www.aegis.org/aidsline/1989/oct/m89a0462.html
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Abstract: An enzyme-linked immunoassay (ELISA) using six recombinant proteins corresponding to large segments of the human immunodeficiency virus type 1 (HIV-1) gag, pol, and env gene products (HIVAGEN; SmithKline Bio-Science Laboratories, Van Nuys, Calif.) was developed to confirm the presence of antibodies to HIV-1 in sera re ...
http://www.aegis.org/aidsline/1989/oct/m89a0265.html
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Abstract: The value of differential cell counts in bronchoalveolar lavage fluid in patients who were serologically positive for the human immunodeficiency virus (HIV) was studied in 30 patients with classified into four groups according to the severity of illness: (1) seven subjects with the AIDS related complex without clinica ...
http://www.aegis.org/aidsline/1989/nov/m89b0274.html
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Abstract: We undertook a prospective study of IgG and IgM anticardiolipin antibodies (ACAs) to determine their clinical significance in patients with acquired immunodeficiency syndrome (AIDS). IgG ACAs were found in 24 (92.3%) of 26 patients with AIDS who were hospitalized for pulmonary complaints (group 1) and in 13 (93%) of 1 ...
http://www.aegis.org/aidsline/1989/nov/m89b0143.html
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Abstract: It is now recognized that HIV can (either directly or indirectly) affect nearly every organ system in the body and that a wide range of clinical manifestations can result from infection with this agent. Some of these appear to result directly from infection with the virus while others may result from the altered immun ...
http://www.aegis.org/aidsline/1989/may/m8950682.html
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Abstract: The authors describe their experience of the infection by the virus of the human immunodeficiency HIV-1 in Burundi . The acquired immunodeficiency syndrome was brought to light in 1983 by the emergence of cryptococcal meningitis, Kaposi s sarcomas, disseminated candidiasis. 109 cas ...
http://www.aegis.org/aidsline/1989/may/m8950479.html
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Abstract: We measured the neutrophil function of 6 patients with AIDS and Kaposi s sarcoma (KS); 22 patients with AIDS-related complex (ARC); and 28 healthy, heterosexual controls. Neutrophils from patients with ARC showed significantly less chemotaxis (P less than or equal to .025) than did those from patients with AIDS and KS ...
http://www.aegis.org/aidsline/1989/mar/m8930208.html
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Abstract: Two hundred eighty-one patients with the acquired immunodeficiency syndrome (AIDS) or advanced AIDS-related complex were enrolled in a double-blind, placebo-controlled trial of the efficacy and safety of orally administered zidovudine (azidothymidine or A ...
http://www.aegis.org/aidsline/1989/mar/m8930201.html
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Abstract: Zidovudine ( AZT ) is of some benefit for selected patients with AIDS-related complex (ARC) or AIDS treated for up to 24 weeks. The activity and toxicity of oral AZT, 200 mg 4-hourly when possible, was evaluated in 365 consecutive patients with ARC (80) ...
http://www.aegis.org/aidsline/1989/mar/m8930084.html
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Abstract: Due to the current absence of curative therapies, patients with AIDS or ARC (AIDS-Related Complex) rely on information to provide them with a sense of control over their lives [Institute of Medicine, National Academy of Sciences, Confronting AIDS: Directions for Public Health, Health Care and Research (1986)]. The pur ...
http://www.aegis.org/aidsline/1989/jun/m8960584.html
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Abstract: Although a variety of cardiac abnormalities have been described in AIDS patients, it is unclear whether these are incidental findings or they presage clinically important heart disease. Also, because AIDS-related complex (ARC) is, in general, a milder form of AIDS, we wondered if echocardiographic abnormalities would ...
http://www.aegis.org/aidsline/1989/jun/m8960244.html
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Abstract: We performed ophthalmologic examinations on 127 subjects with or at risk for human immunodeficiency virus (HIV) infection over a one-year period to determine the prevalence and significance of retinal cotton-wool spots and hemorrhages (AIDS-related retinal microvasculopathy). Of 26 asymptomatic homosexual men, of whom ...
http://www.aegis.org/aidsline/1989/jun/m8960076.html
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Abstract: To investigate whether the human immunodeficiency virus (HIV) infection or the abuse of narcotic drugs or other viral infections may be responsible for immunologic abnormalities in parenteral drug abusers, sera from 168 consecutive individual patients were collected from 1985 to 1986. The sera were tested for antibody ...
http://www.aegis.org/aidsline/1989/jun/m8960052.html
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Abstract: Functional hyposplenia can be defined as decreased splenic phagocytosis. A case of functional hyposplenia is reported in a child with AIDS-related complex. ...
http://www.aegis.org/aidsline/1989/jul/m8970751.html
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Abstract: The ability of alveolar macrophages (AM) to release hydrogen peroxide (H2O2), an indicator of AM function, was studied in five children with the acquired immunodeficiency syndrome (AIDS) related complex and, for comparison, in 11 children without disorders of the lung parenchyma. In the AIDS-related complex group, pul ...
http://www.aegis.org/aidsline/1989/jul/m8970672.html
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Abstract: We have investigated up to the beginning of 1987 114 patients with congenital clotting disorders. 84 had received plasma and/or clotting factors concentrates. 18 out of 84 (21%) had leukopenia, thrombocytopenia, or both. 64 out of 84 (76%) had been infected by hepatitis B virus. The great majority of them (62 out 64) ...
http://www.aegis.org/aidsline/1989/jul/m8970013.html
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Abstract: We assessed the effect of antiviral therapy on serum human immunodeficiency virus core antigen (HIV-Ag) levels in patients enrolled in the phase II trial on zidovudine for acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. Human immunodeficiency virus core antigen was detected in 45% of subjects at en ...
http://www.aegis.org/aidsline/1989/jan/m8910227.html
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Abstract: AIDS patients often develop a conspicuous although functionally ineffective hypergammaglobulinaemia. We have treated four patients affected by AIDS or AIDS-related complex (ARC) with repeated courses of plasmaexchange coupled with immunoglobulin infusions. The schedule of each course was as follows: one plasmapheresis ...
http://www.aegis.org/aidsline/1989/feb/m8920470.html
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Abstract: The presence and specificity of anti-lymphocyte antibodies (ALA) was investigated in sera from male homosexuals with AIDS-Related Complex (ARC) as well as healthy homosexuals. Individuals in the healthy homosexual group had no detectable antibodies to human immunodeficiency virus (HIV). Antibodies reactive with normal ...
http://www.aegis.org/aidsline/1989/feb/m8920209.html
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Abstract: Sixty patients with acquired immune deficiency syndrome (AIDS) or AIDS-related complex were treated on a locked inpatient psychiatric unit over a 30-month period. The wide range of mental disorders exhibited by these patients, key aspects of patient management, and the difficulty in psychiatric differential diagnosis ...
http://www.aegis.org/aidsline/1989/dec/m89c0437.html
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Abstract: A cross-sectional study of 128 individuals infected with human immunodeficiency virus type 1 (HIV-1) was conducted to determine the correlation of reverse transcriptase-inhibiting (RTI) antibody to clinical disease. Thirty-two individuals were studied in each of four clinical groups: asymptomatic individuals, those wi ...
http://www.aegis.org/aidsline/1989/dec/m89c0022.html
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Abstract: Relatively low dose treatment (150 mg/kg, once per two weeks) of a intravenous immunoglobulin (IVI) preparation has shown a beneficial effect on CD4/CD8 ratio and CD4 cell counts in two patients with AIDS-related complex (ARC). Since ARC generally progresses to AIDS with a marked reduction of CD4 cells or a marked inv ...
http://www.aegis.org/aidsline/1989/aug/m8980724.html
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Abstract: Total immunoglobulin (Ig) and IgG subclass levels were measured in 72 patients with AIDS or AIDS-related complex (ARC). IgG2 subclass levels were found to be significantly decreased in the AIDS/ARC patients with pyogenic infections compared with both similar individuals without bacterial disease and the HIV-negative c ...
http://www.aegis.org/aidsline/1989/aug/m8980214.html
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Abstract: PURPOSE: In 1985, we reported that acquired immunodeficiency syndrome (AIDS) developed in 14 of 81 (17%) men with generalized lymphadenopathy followed prospectively for an average of 13 months. The presence of oral thrush or constitutional symptoms, or both, or severely impaire ...
http://www.aegis.org/aidsline/1989/aug/m8980068.html
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Abstract: Methylphenidate or dextroamphetamine was used to treat 17 of 32 patients with AIDS-related complex who were referred for neuropsychiatric evaluation of symptoms representative of cognitive and/or affective dysfunction. All 17 patients were found to have some degree of cognitive impairment. Psychiatric diagnoses includ ...
http://www.aegis.org/aidsline/1989/apr/m8940113.html
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Abstract: STUDY OBJECTIVE: To determine the safety and efficacy of dideoxycytidine in patients with the acquired immunodeficiency syndrome (AIDS) or advanced AIDS-related complex. DESIGN: A partially randomized phase I and II outpatient, dose-ranging study. SETTING: Four university medical centers involving government-supported ...
http://www.aegis.org/aidsline/1989/apr/m8940066.html
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