|   | ![]() Your Search for active immunization matched 135 Documents (Page 1 of 5). Results Indexed by relevance. |
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PROPHYLACTIC AND THERAPEUTIC IMMUNIZATION AGAINST AIDS: THEORETICAL CONSIDERATIONS UNDERLYING A MODIFIED NONINFECTIOUS WHOLE VIRUS APPROACH (100%) Abstract: Post-HIV infection events may be modulated by (1) prepriming the immune system by active immunization of HIV seronegatives, to respond anamnestically to subsequent HIV exposure, to prevent establishment of infection and/or disease or (2) through active and/or passive immunization of HIV seropositives, to prevent, arre ... http://www.aegis.org/aidsline/1991/dec/m91c4091.html File Name: m91c4091.html, Size: 11KB, Last Modified: Saturday, December 28, 1991 at 8:12:04 PM |
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Experimental immune-mediated blepharoconjunctivitis in rats induced by immunization with ragweed pollen. (70%) Abstract: BACKGROUND: A study was performed to compare the effects of immunization with ragweed pollen (RW) in two different adjuvants on the characteristics of a previously described model of experimental immune-mediated blepharoconjunctivitis (EC) in rats. METHODS: Lewis or Brown Norway (B ... http://www.aegis.org/aidsline/2000/nov/a00b0800.html File Name: a00b0800.html, Size: 11KB, Last Modified: Tuesday, November 28, 2000 at 8:12:04 PM |
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Autoimmune ovarian inflammation triggered by proinflammatory (Th1) T cells is compatible with normal ovarian function in mice. (70%) Abstract: The detection of noninfectious ovarian inflammation (oophoritis) and serum ovarian autoantibodies in a patient with premature ovarian failure is indicative of an autoimmune etiology. The mechanisms of autoimmune ovarian injury leading to loss of function are currently unknown. In this study we investigated the impact ... http://www.aegis.org/aidsline/1999/nov/a99b0223.html File Name: a99b0223.html, Size: 9KB, Last Modified: Sunday, November 28, 1999 at 8:12:04 PM |
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Anti-idiotype immunomodulation of experimental anti-phospholipid syndrome via effect on Th1/Th2 expression. (70%) Abstract: Mice with experimental anti-phospholipid syndrome (APS), induced by active immunization with a human anti-cardiolipin MoAb (H-3), were treated with mouse anti-idiotypic MoAb (anti-H3, named S2.9) and with an irrelevant anti-idiotype. The immunized mice produced high titres of mouse anti-cardiolipin antibodies along wi ... http://www.aegis.org/aidsline/1999/sep/a9990200.html File Name: a9990200.html, Size: 9KB, Last Modified: Tuesday, September 28, 1999 at 8:12:04 PM |
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Is immunotherapy of Pneumocystis carinii pneumonia (PCP) feasible? (70%) Abstract: PCP is a classic opportunistic infection which causes significant morbidity and mortality among immunocompromised patients, especially those with AIDS. Passive immunization has been successful in the prevention or treatment of several infections, including some in immunodeficient individuals. Active immunization to pri ... http://www.aegis.org/aidsline/1997/jul/m9770927.html File Name: m9770927.html, Size: 8KB, Last Modified: Monday, July 28, 1997 at 8:12:04 PM |
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Active immunization in HIV-infected patients. (70%) Abstract: Patients infected with human immunodeficiency virus (HIV) are at risk for various viral and bacterial infections. Active immunization with currently available vaccines may reduce the risk of some vaccine-preventable diseases in this population. Based on available data, most vaccines used in the ... http://www.aegis.org/aidsline/1997/jan/m9710404.html File Name: m9710404.html, Size: 8KB, Last Modified: Tuesday, January 28, 1997 at 8:12:04 PM |
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AEGiS-04CROI: Is immunotherapy of Pneumocystis carinii pneumonia (PCP) feasible? (70%) Abstract: PCP is a classic opportunistic infection which causes significant morbidity and mortality among immunocompromised patients, especially those with AIDS. Passive immunization has been successful in the prevention or treatment of several infections, including some in immunodeficient individuals. Active immunization to p ... http://www.aegis.org/conferences/croi/1997/s5.html File Name: s5.html, Size: 5KB, Last Modified: Wednesday, January 22, 1997 at 8:12:04 PM |
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Efficacy of experimental FIV vaccines. (70%) Abstract: Active immunization with inactivated whole infected cell or cell-free feline immunodeficiency virus (FIV) vaccines has protected > 90% of cats (55 of 58) against intraperitoneal challenge infection with a low dose (10 ID 50) of either homologous FIV or a heterologous FIV strain differing by 11% in outer envelope amino ... http://www.aegis.org/aidsline/1993/nov/m93b4201.html File Name: m93b4201.html, Size: 8KB, Last Modified: Sunday, November 28, 1993 at 8:12:04 PM |
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AEGiS-09IAC: Efficacy of experimental FIV vaccines. (70%) Abstract: Active immunization with inactivated whole infected cell or cell-free feline immunodeficiency virus (FIV) vaccines has protected > 90% of cats (55 of 58) against intraperitoneal challenge infection with a low dose (10 ID 50) of either homologous FIV or a heterologous FIV strain differing by 11% in outer envelope amino ... http://www.aegis.org/conferences/iac/1993/wsa235.html File Name: wsa235.html, Size: 5KB, Last Modified: Sunday, June 06, 1993 at 8:12:04 PM |
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Active immunization of recombinant gp160/p24 vaccine (VAXSYN(R)) in HIV-infected individuals: a community-based phase I/II trial of toxicity and immunogenicity. (70%) Abstract: OBJECTIVE: To evaluate the toxicity and immunogenicity of recombinant gp160 envelope precursor and p24 core proteins in HIV-infected individuals. METHODS: Patient Selection: 30 individuals with HIV infection were randomly immunized regardless of CD4 cell count, with baculovirus expressed gp160 and p24 vaccines. (VAXSY ... http://www.aegis.org/aidsline/1991/dec/m91c3615.html File Name: m91c3615.html, Size: 10KB, Last Modified: Saturday, December 28, 1991 at 8:12:04 PM |
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AEGiS-07IAC: Active immunization of recombinant gp160/p24 vaccine (VAXSYN(R)) in HIV-infected individuals: a community-based phase I/II trial of toxicity and immunogenicity. (70%) Abstract: <p><b>OBJECTIVE</b>: To evaluate the toxicity and immunogenicity of recombinant gp160 envelope precursor and p24 core proteins in HIV-infected individuals.</p> <p><b>METHODS</b>: Patient Selection: 30 individuals with HIV infection were randomly immunized regardless of CD4 cell count, with baculovirus expressed gp16 ... http://www.aegis.org/conferences/iac/1991/ma1343.html File Name: ma1343.html, Size: 5KB, Last Modified: Sunday, June 16, 1991 at 8:12:04 PM |
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1990 progress report on clinical trial phase 1 concerning the preparation a vaccine against AIDS. (70%) Abstract: In the previous annual reports (1, 2, 3) we presented the experimental results of an active immunization against HIV based on priming with recombinant vaccine (rV) expressing HIV gp160 with analogous lymphocytes infected with rV and subsequently fixed. We showed that this immunization led to an in vitro protective imm ... http://www.aegis.org/aidsline/1990/dec/m90c1100.html File Name: m90c1100.html, Size: 9KB, Last Modified: Friday, December 28, 1990 at 8:12:04 PM |
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Active immunization of recombinant produced GP 160 in patients with early HIV infection: phase 1 trial immunogenicity and toxicity. (70%) Abstract: OBJECTIVE: To evaluate the immunogenicity and toxicity of recombinant GP 160 vaccine in patients with early HIV infection. METHODS: Patient Selection: Walter Reed Stage 1 and 2 HIV infection were immunized with a baculovirus expressed gp 160 vaccine (MGS). Vaccine Schedule: Patients were randomized into 6 different gr ... http://www.aegis.org/aidsline/1990/dec/m90c1658.html File Name: m90c1658.html, Size: 10KB, Last Modified: Friday, December 28, 1990 at 8:12:04 PM |
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THE EPIDEMIOLOGY OF AIDS: IMMUNIZATION (70%) Abstract: Immunization against HIV-1 can take three forms: (1) pre-exposure, active immunization; (2) post-exposure, active immunization; and (3) post-exposure, passive immunization. Progress in each of these areas is discussed. Vaccine development has been slowed by the limited understanding of the natural history of HIV-1 inf ... http://www.aegis.org/aidsline/1990/dec/m90c3724.html File Name: m90c3724.html, Size: 9KB, Last Modified: Friday, December 28, 1990 at 8:12:04 PM |
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AEGiS-06IAC: 1990 progress report on clinical trial phase 1 concerning the preparation a vaccine against AIDS. (70%) Abstract: In the previous annual reports (1, 2, 3) we presented the experimental results of an active immunization against HIV based on priming with recombinant vaccine (rV) expressing HIV gp160 with analogous lymphocytes infected with rV and subsequently fixed. We showed that this immunization led to an in vitro protective immu ... http://www.aegis.org/conferences/iac/1990/1145.html File Name: 1145.html, Size: 5KB, Last Modified: Wednesday, June 20, 1990 at 8:12:04 PM |
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AEGiS-06IAC: Active immunization of recombinant produced GP 160 in patients with early HIV infection: phase 1 trial immunogenicity and toxicity. (70%) Abstract: <p><b>OBJECTIVE</b>: To evaluate the immunogenicity and toxicity of recombinant GP 160 vaccine in patients with early HIV infection.</p> <p><b>METHODS</b>: Patient Selection: Walter Reed Stage 1 and 2 HIV infection were immunized with a baculovirus expressed gp 160 vaccine (MGS). Vaccine Schedule: Patients were rand ... http://www.aegis.org/conferences/iac/1990/sb495.html File Name: sb495.html, Size: 6KB, Last Modified: Wednesday, June 20, 1990 at 8:12:04 PM |
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Effect of immunization on HTLV-I infection in rabbits. (35%) Abstract: Two groups of 3 rabbits, each immunized with heat-inactivated HTLV-I or a synthetic env peptide (env175-196), developed antibodies to viral proteins including gp68 and gp46. These immunized rabbits were then challenged with a transfusion of blood from HTLV-I-infected rabbits of the opposite sex. After transfusion chal ... http://www.aegis.org/aidsline/1989/nov/m89b0402.html File Name: m89b0402.html, Size: 9KB, Last Modified: Wednesday, January 07, 2009 at 5:29:02 AM |
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[AIDS: possibilities of active immunization] (35%) Abstract: The development of an AIDS vaccine represents a major challenge for medical research. Efforts are undertaken for the production of appropriate immunogens in sufficient quantity and purity, especially by the use of recombinant DNA technology. Unfortunately, all immunization experiments using chimpanzees were negative s ... http://www.aegis.org/aidsline/1989/mar/m8930177.html File Name: m8930177.html, Size: 8KB, Last Modified: Wednesday, January 07, 2009 at 5:27:20 AM |
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Active immunization against hepatitis B: immunogenicity of a recombinant DNA vaccine in females, heterosexual and homosexual males. (35%) Abstract: Three groups of subjects (58 females, 54 heterosexual males, and 50 homosexual males) received three doses of a recombinant DNA yeast-derived hepatitis B vaccine according to a 0, 1, and 6 month vaccination schedule. Local and general side effects were mild. Seroconversion rates after three injections were not signifi ... http://www.aegis.org/aidsline/1988/mar/m8830166.html File Name: m8830166.html, Size: 9KB, Last Modified: Wednesday, January 07, 2009 at 5:17:33 AM |
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[Transient HIV-antibody positive tests in heart transplantation patients after repeated administration of a CMV immune globulin preparation] (35%) Abstract: After repeated administration of relatively high doses of a cytomegalovirus immunoglobulin preparation to two patients after heart transplantation, both the ELISA and the immuno-blot tests became temporarily positive (for 21 and 41 days, respectively) to HIV antibodies. The ... http://www.aegis.org/aidsline/1987/may/m8750089.html File Name: m8750089.html, Size: 9KB, Last Modified: Wednesday, January 07, 2009 at 5:05:09 AM |
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AEGiS-11CROI: Use of Solvent Treated SIV to Induce/Augment SIV-specific CD4+ and CD8+ T Cell Memory Responses in Mice: A Model for a New Therapeutic Vaccination Strategy against HIV Infection. (35%) Abstract: BACKGROUND: Novel strategies need to be identified and studied for the immune reconstitution of HIV-infected humans to supplement HAART. Current chemotherapeutic strategies, while highly effective, are not without significant side effects, and are associated with increased risk of selection for multi-drug resistant HIV ... http://www.aegis.org/conferences/croi/2004/520.html File Name: 520.html, Size: 7KB, Last Modified: Sunday, February 08, 2004 at 8:12:04 PM |
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AEGiS-10CROI: CD4+ and CD8+ T-cell Responses are Induced in Chronically HIV-1 Infected Patients after Immunization by a Lipopeptide Vaccine. (35%) Abstract: <p><b>BACKGROUND:</b> We have shown previously that an anti-HIV lipopeptide vaccine using large peptides injected to HIV-uninfected volunteers is well tolerated and is able to induce specific CD4 + and CD8 + T-cell responses (ANRS, VAC 04 Trial). The same mixture of HIV-1 lipopeptide vaccine was injected in chronically ... http://www.aegis.org/conferences/croi/2003/643.html File Name: 643.html, Size: 7KB, Last Modified: Monday, February 10, 2003 at 8:12:04 PM |
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AEGiS-10CROI: Dichotomy in Cross-clade Reactivity of Sera: Implications for the Development of Active and Passive Immunotherapy. (35%) Abstract: <p><b>BACKGROUND:</b> Using sera and virions from clade B infected individuals, we have shown previously that serum antibodies reactive with primary isolate virions correlates with virus neutralization and stable disease. While clade B is responsible for the vast majority of infections in North America and parts of Eur ... http://www.aegis.org/conferences/croi/2003/411.html File Name: 411.html, Size: 6KB, Last Modified: Monday, February 10, 2003 at 8:12:04 PM |
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AEGiS-9CROI: Impaired Responses to Immunization in HIV-Infection despite CD4+ T-Cell Restoration after Suppressive Antiretroviral Therapy. (35%) Abstract: BACKGROUND: Responses to immunization are indices of general immune competence requiring integrity of both afferent and efferent limbs of the immune system. This study was designed to examine the responses to immunization with recall and neo-antigens in persons with normal CD4<sup>+</sup> T-cell counts after successful ... http://www.aegis.org/conferences/croi/2002/504-m.html File Name: 504-m.html, Size: 7KB, Last Modified: Sunday, February 24, 2002 at 8:12:04 PM |
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[411] ACTIVE IMMUNIZATION AGAINST HIV-1 SPECIFIC ANTIGENS AND AGAINST HLA ALLOANTIGENS USING AN INACTIVATED HIV-1 IMMUNOGEN: IMPLICATION FOR PREVENTION AND TREATMENT OF HIV DISEASE (35%) Abstract: These findings indicates that therapeutic vaccination induces immune modulation and enhances both humoral and cellular HIV-1 specific immune responses and alloresponses, which may have practical significance ... http://www.aegis.org/conferences/iashivpt/2001/411.html File Name: 411.html, Size: 7KB, Last Modified: Monday, July 09, 2001 at 6:29:23 AM |
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[Risk of transmission of viral disease by needle punctures and cuts in hospital health care workers] (35%) Abstract: The accidental exposure of the health care workers (HCW) to blood and blood products constitutes a danger for transmission of blood-borne pathogens and the development of severe diseases. Most attention is focused on exposure to the viruses of hepatitis B, C and human immunodeficiency. The objectives of this prospectio ... http://www.aegis.org/aidsline/2000/nov/a00b1100.html File Name: a00b1100.html, Size: 10KB, Last Modified: Tuesday, November 28, 2000 at 8:12:04 PM |
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DNA vaccines for influenza virus: differential effects of maternal antibody on immune responses to hemagglutinin and nucleoprotein. (35%) Abstract: Maternal antibody is the major form of protection from disease in early life when the neonatal immune system is still immature; however, the presence of maternal antibody also interferes with active immunization, placing infants at risk for severe bacterial and viral infection. We tested the ability of intramuscular a ... http://www.aegis.org/aidsline/2000/nov/a00b0512.html File Name: a00b0512.html, Size: 10KB, Last Modified: Tuesday, November 28, 2000 at 8:12:04 PM |
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Persisting HIV-1 replication triggered by acute hepatitis A virus infection. (35%) Abstract: We report the case of two patients in whom acute hepatitis A was associated with a marked and prolonged increase in human immunodeficiency virus type 1 (HIV-1) viral load. Although in one patient the rise in HIV-1 RNA might also have been related to the interruption of antiretroviral therapy, we also observed a simila ... http://www.aegis.org/aidsline/2000/nov/a00b0220.html File Name: a00b0220.html, Size: 9KB, Last Modified: Tuesday, November 28, 2000 at 8:12:04 PM |
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Is there a role for immunotherapy in controlling HIV infection? (35%) Abstract: Although HAART restores immune function in patients with HIV infection, restoration is incomplete. Functional restoration is seen primarily in responses to antigens that are prevalent in HIV-infected persons. Immunization is required to restore responses to antigens that are not predictably present. As an exception, H ... http://www.aegis.org/aidsline/2000/sep/a0091110.html File Name: a0091110.html, Size: 9KB, Last Modified: Thursday, September 28, 2000 at 8:12:04 PM |
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Vaccine adverse events in the new millennium: is there reason for concern? (35%) Abstract: As more and more infectious agents become targets for immunization programmes, the spectrum of adverse events linked to vaccines has been widening. Although some of these links are tenuous, relatively little is known about the immunopathogenesis of even the best characterized vaccine-associated adverse events (VAAEs). ... http://www.aegis.org/aidsline/2000/jul/a0071429.html File Name: a0071429.html, Size: 9KB, Last Modified: Friday, July 28, 2000 at 8:12:04 PM |
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