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Abstract: A cheap, generic treatment used against herpes can also lower HIV viral load, researchers reported Wednesday. However, acyclovir works against HIV only in tissues that are also infected with herpes. The findings could help explain why some studies have shown that patients taking acyclovir have a lower HIV viral load, w ...
http://www.aegis.org/news/ads/2008/ad081742.html
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Abstract: TY - ABST PB - XVII International AIDS Conference. 3-8 August 2008, Mexico City, Mexico SN - 978-92-95069-05-3 U1 - WEPE0248 T1 - Strengthening HIV prevention by adding acyclovir roll-out strategy through the STI (sexually transmitted infection) control programme in Botswana p>b>ISSUES<b> HIV preval ...
http://www.aegis.org/conferences/iac/2008/abs03048.txt
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Abstract: Les personnes infectées par le VIH peuvent aussi être infectées par d'autres microbes tels que ceux qui sont responsables de l'herpès. Quand ces coinfections font rage, elles peuvent accroître la production de VIH, et peut-être ainsi accélérer le déclin du système immunitaire. ...
http://www.aegis.org/pubs/catie/1998/catf8504.html
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Abstract: People infected with HIV may also be co-infected with other microbes such as those that cause herpes. When these co-infections flare, they can increase production of HIV, perhaps leading to faster destruction of the immune system. So some doctors think that regular use of anti-herpes drugs may keep these viruses from b ...
http://www.aegis.org/pubs/catie/1998/cate8504.html
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Abstract: Background ...
http://www.aegis.org/pubs/catie/1996/cate7406.html
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Abstract: Acyclovir or similar agents with activity against Epstein-Barr virus (EBV) theoretically may prevent non-Hodgkin s lymphoma (NHL) in AIDS. A case-control study of 29 patients with AIDS-related NHL and 58 matched control subjects assessed the ...
http://www.aegis.org/aidsline/2000/oct/a00a0345.html
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Abstract: Neurological damage in Herpes simplex type 1 encephalitis results from neuronal cell death secondary to viral invasion, and from inflammatory changes and cerebral oedema secondary to the immune response to the virus. Corticosteroids could have an important role in the management of Herpes simplex encephalitis because ...
http://www.aegis.org/aidsline/2000/aug/a0080674.html
File Name: a0080674.html, Size: 11KB, Last Modified: Monday, August 28, 2000 at 8:12:04 PM
Abstract: OBJECTIVE: To report the epidemiological and clinical features of acyclovir-resistant herpes zoster and to evaluate the efficacy of foscarnet. DESIGN AND METHODS: Retrospective study of all consecutive cases of acyclovir-resistant herpes zoster. Herpes zoster was confirmed by isolation of VZV in culture. ...
http://www.aegis.org/aidsline/1998/dec/m98c3627.html
File Name: m98c3627.html, Size: 10KB, Last Modified: Tuesday, December 29, 1998 at 6:29:23 AM
Abstract: Acyclovir-Resistant Genital Herpes Found in Person with Healthy Immune System. News from NIAID - December 8, 1993 by National Institute of Allergy and Infectious Diseases, National Institutes of Health Researchers at theNational Institute of Allergy and Infectious Diseases. NIAID. report the first document ...
http://www.aegis.org/news/nih/1993/nih93095.html
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Abstract: Acyclovir-Resistant Genital Herpes Found in Person with Healthy Immune System. News from NIAID - December 8, 1993 National Institute of Allergy and Infectious Diseases, National Institutes of HealthResearchers at the. National Institute of Allergy. and Infectious Diseases (. NIAID. ...
http://www.aegis.org/news/niaid/1993/cdc93095.html
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Abstract: <p><b>OBJECTIVE:</b> To report the epidemiological and clinical features of acyclovir-resistant herpes zoster and to evaluate the efficacy of foscarnet. DESIGN AND </p> <p><b>METHODS:</b> Retrospective study of all consecutive cases of acyclovir-resistant herpes zoster. Herpes zoster was confirmed by isolation o ...
http://www.aegis.org/conferences/iac/1998/32269.html
File Name: 32269.html, Size: 7KB, Last Modified: Sunday, June 28, 1998 at 8:12:04 PM
Abstract: A 5-year-old girl with a kidney transplant developed post-transplant Epstein-Barr virus-induced lymphoproliferative disease. ...
http://www.aegis.org/pubs/medline/1998/jan/m9819293.html
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Abstract: Objective: To evaluate the effect of acyclovir use on survival in HIV seropositive persons enrolled in an observational study by 17 units conducting community-based clinical trials in the United States . Design: Analyses were conducted on 2,368 HI ...
http://www.aegis.org/aidsline/1996/nov/m96b0441.html
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Abstract: Herpes simplex virus (HSV) infections are very common in the general population and can be treated with the nucleoside analogue acyclovir. Acyclovir is initially phosphorylated intracellularly in HSV-infected cells by a viral-specific thymidine kinase to acyclovir-monophosphate. ...
http://www.aegis.org/aidsline/1996/apr/m9640260.html
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Abstract: Use of acyclovir was not associated with improved survival in this large cohort of 2,368 HIV-infected patients, and our findings suggest that intermittent use of acyclovir may be associated with an increased risk of death. Selection biases could have a marked effect on these findings as well as findings from other obse ...
http://www.aegis.org/conferences/croi/1996/367.html
File Name: 367.html, Size: 8KB, Last Modified: Sunday, January 28, 1996 at 8:12:04 PM
Abstract: Two reports submitted at the Second National Conference on Human Retroviruses reignited the controversy surrounding acyclovir s potential effect on survival in HIV-infected persons. One study found no differences in survival between those using acyclovir and those not using the drug, however, it is argued that the stu ...
http://www.aegis.org/aidsline/1995/dec/m95c3146.html
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Abstract: Objective: To determine if P24 antigenaemia conversion was different in patients receiving AZT versus AZT/ Acyclovir . Methods: Sample consisted of 68 HIV seropositive subjects who were participating in the 3rd ye ...
http://www.aegis.org/aidsline/1995/dec/m95c1711.html
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Abstract: For several years there has been confusion over the possibility that the anti-herpes drug acyclovir can prolong the survival of people with AIDS. Three studies published in recent years have suggested that the drug does improve the life expectancy of people with low CD4 counts, but a further two studies reported last m ...
http://www.aegis.org/pubs/atu/1995/atu2701.html
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Abstract: OBJECTIVE: To examine the effect of acyclovir use on disease progression and survival in zidovudine treated HIV + individuals. METHODS: Prospective cohort study of gay and bisexual men seen semiannually. Intent to treat Cox models were fit to determine the relationship between use of acyclovir (modelled as a time depet ...
http://www.aegis.org/aidsline/1994/dec/m94c3621.html
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Abstract: OBJECTIVE: To determine the efficacy of high-dose oral acyclovir in preventing cytomegalovirus ( CMV ) and other herpesvirus disease in patients with advanced HIV disease and to evaluate its effect on patient survival. DESIGN: ...
http://www.aegis.org/aidsline/1994/nov/m94b0367.html
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Abstract: The delivery of increased plasma acyclovir concentrations following oral valaciclovir is achieved in advanced HIV, BMT, liver disease and ESRD patients. This should enable effective oral treatment and suppression of herpes viruses including CMV in a range of patient populations. ...
http://www.aegis.org/conferences/hiv-glasgow/1994/p59.html
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Abstract: The acyclic nucleoside phosphonate (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) was used topically for the treatment of persistent mucocutaneous infections in two cases. One patient with AIDS suffered from a perineal lesion due to infection with herpes simplex virus type 2 (HSV-2) and did not respond to ...
http://www.aegis.org/aidsline/1994/oct/m94a0262.html
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Abstract: OBJECTIVE: To examine the effect of acyclovir use on disease progression and survival in human immunodeficiency virus (HIV)-seropositive persons treated with zidovudine. SETTING: Four university-based or -affiliated clinics. DESIGN: Prospective cohort study of homosexual and bis ...
http://www.aegis.org/aidsline/1994/sep/m9490226.html
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Abstract: <p><b>OBJECTIVE</b>: To examine the effect of acyclovir use on disease progression and survival in zidovudine treated HIV + individuals.</p> <p><b>METHODS</b>: Prospective cohort study of gay and bisexual men seen semiannually. Intent to treat Cox models were fit to determine the relationship between use of acyclovi ...
http://www.aegis.org/conferences/iac/1994/060b.html
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Abstract: Infection with herpes simplex viruses (HSVs) resistant to treatment with acyclovir (9-[(2-hydroxyethoxy)-methyl]guanine, Zovirax ) is a growing clinical problem in patients with AIDS and other immunosuppressed states. Most virus isolates resistant to acyclovir are deficient or de ...
http://www.aegis.org/aidsline/1994/mar/m9430294.html
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Abstract: Valaciclovir (BW256U87) is an L-valyl ester of acyclovir , which is extensively and almost completely converted to acyclovir. In healthy human volunteers, single valaciclovir doses of 100-1000 mg resulted in dose-proportional increases in acyclovir area under the curve (AUC). The ...
http://www.aegis.org/aidsline/1994/mar/m9430852.html
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Abstract: Acyclovir was approved over a decade ago by the FDA as a treatment for herpes. It has proven to be an excellent anti-herpes drug, but its role in fighting HIV has not yet been firmly established. CMV is one of the opportunistic infections for which we have not developed an effective prophylaxis. Since CMV is a cousin t ...
http://www.aegis.org/pubs/bala/1994/ba940301.html
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Abstract: Agents available to treat herpesvirus infections include idoxuridine, trifluridine, vidarabine and acyclovir for the topical treatment of herpetic eye infections; vidarabine and acyclovir for the systemic (intravenous) treatment of herpes encephalitis; acyclovir for the topical ...
http://www.aegis.org/aidsline/1994/jan/m9410555.html
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Abstract: Acyclovir-Resistant Genital Herpes Found in Person with Healthy Immune System. News from NIAID - December 8, 1993 National Institute of Allergy and Infectious Diseases, National Institutes of HealthResearchers at the National Institute of Allergy and Infectious Diseases (. NIAID. ...
http://www.aegis.org/pubs/cdc_fact_sheets/1993/cdc93095.html
File Name: cdc93095.html, Size: 7KB, Last Modified: Saturday, January 08, 1994 at 10:00:00 PM
Abstract: OBJECTIVES: To evaluate the efficacy and safety of high dose acyclovir as prophylaxis against CMV disease in HIV seropositives with low CD4 positive cell (CD4) counts and to ascertain any survival benefit. METHODS: Three h ...
http://www.aegis.org/aidsline/1992/dec/m92c5336.html
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