ALL AIDSLINE ASK THE DOC CONFERENCES --5th IAS HIV Pathog & Treat --4th IAS HIV Pathog & Treat --3rd IAS HIV Pathog & Treat --2nd IAS HIV Pathog & Treat --1st IAS HIV Pathog & Treat -Intl AIDS Conferences --17th Int Conf AIDS: Toronto (2006) --16th Int Conf AIDS: Toronto (2006) --15th Int Conf AIDS: Bangkok (2004) --14th Int Conf AIDS: Barcelona (2002) --13th Int Conf AIDS: Durban (2000) --12th Int Conf AIDS: Geneva (1998) --11th Int Conf AIDS: Vancouver --10th Int Conf AIDS: Yokohoma --9th Int Conf AIDS: Berlin --8th Int Conf AIDS: Amsterdam --7th Int Conf AIDS: Florence --6th Int Conf AIDS: San Franciso --5th Int Conf AIDS: Montreal --4th Int Conf AIDS: Stockholm --3rd Int Conf AIDS: Washington --2nd Int Conf AIDS: Paris --1st Int Conf AIDS: Atlanta --9th Intl Cong. Drug Therapy: Glasgow 2008 --8th Intl Cong. Drug Therapy: Glasgow 2006 --7th Intl Cong. Drug Therapy: Glasgow 2004 --6th Intl Cong. Drug Therapy: Glasgow 2002 --5th Intl Cong Drug Therapy: Glasgow 2000 --3rd Intl Cong Drug Therapy: Glasgow 1996 --2nd Intl Cong Drug Therapy: Glasgow 1994 --10th Lipo: London, UK --9th Lipo: Sydney, Australia --8th Lipo: San Francisco --7th Lipo: Dublin, Ireland --6th Lipo: Washington, DC --5th Lipo: Paris, France --4th Lipo: San Diego --3rd Lipo: Athens, Greece --2nd Lipo: Toronto, Canada --1st Lipo: San Diego --15th Conf Retroviruses Opportunistic Infect --14th Conf Retroviruses Opportunistic Infect --13th Conf Retroviruses Opportunistic Infect --12th Conf Retroviruses Opportunistic Infect --11th Conf Retroviruses Opportunistic Infect --10th Conf Retroviruses Opportunistic Infect --9th Conf Retroviruses Opportunistic Infect --8th Conf Retroviruses Opportunistic Infect --7th Conf Retroviruses Opportunistic Infect --6th Conf Retroviruses Opportunistic Infect --5th Conf Retroviruses Opportunistic Infect --4th Conf Retroviruses Opportunistic Infect --3rd Conf Retroviruses Opportunistic Infect --2nd Conf Retroviruses Opportunistic Infect --1st Conf Retroviruses Opportunistic Infect --2005 Natl HIV Prev Conf --2003 Natl HIV Prev Conf --1999 Natl HIV Prev Conf --18th Intl Wkshop HIV Drug Resistance --17th Intl Wkshop HIV Drug Resistance --16th Intl Wkshop HIV Drug Resistance --15th Intl Wkshop HIV Drug Resistance --14th Intl Wkshop HIV Drug Resistance --13th Intl Wkshop HIV Drug Resistance --12th Intl Wkshop HIV Drug Resistance --11th Intl Wkshop HIV Drug Resistance --3rd Intl Wkshop HIV Drug Resistance --5th Intl Wkshop on HIV Drug Resistance & Treatment Strategies --4th Intl Wkshop on HIV Drug Resistance & Treatment Strategies --1st Intl Wkshop on HIV Drug Resistance & Treatment Strategies --15th British HIV Ass'n Conf 2009 --14th British HIV Ass'n Conf 2008 --13th British HIV Ass'n Conf 2007 --12th British HIV Ass'n Conf 2006 --11th British HIV Ass'n Conf 2005 --10th British HIV Ass'n Conf 2004 -- 9th British HIV Ass'n Conf 2003 -- 8th British HIV Ass'n Conf 2002 -- 7th British HIV Ass'n Conf 2001 --9th European AIDS Conf. --8th European AIDS Conf. FACT SHEETS --AIDS Treatment Data Network LAW NEWS SERVICES --AIDS Daily Summary --Agence France-Presse --Asia Times --Associated Press --Bay Area Reporter --BBC On-Line --Bangkok Post --Business Wire --CATIE --Chicago Tribune --FDA News --Inter Press Service --Integrated Regional Information Network --Los Angeles Times --Mail & Guardian --Miami Herald --Newsday --New Vision --New York Times --OC Weekly --PRNewswire --Reuters --San Francisco Chronicle --San Francisco Examiner --Sunday Times --UNAIDS --United Press International --Voice of America --Wall Street Journal --Washington Blade PUBLICATIONS --ACRIA --AIDS Treatment News --AIDS Weekly Plus --amfAR --Being Alive --BETA --BMC AIDS Res Therapy --CATIE --Emerging Infectious Diseases --Gay Men's Health Crisis --HIV Education Project --HIV Treatment Bulletin --IAPAC --IAVI --MMWR --Project Inform PLOS --PLOS Biology --PLOS Medicine --PLOS One --PLOS Pathogens --RITA --Treatment Action Group --Women Alive TOPICS Your Search for adeno-associated virus matched 117 Documents (Page 1 of 4). Results Indexed by relevance.
1.	Dual-target inhibition of HIV-1 in vitro by means of an adeno-associated virus antisense vector. (100%) Abstract: An adeno-associated virus vector encoding an antisense RNA was used to transduce stable intracellular resistance to human immunodeficiency virus-1 (HIV-1) in human hemopoietic and non-hemopoietic cell lines. The antisense targets are present in all HIV-1 transcripts and include the TAR sequence, which is critical for ... http://www.aegis.org/aidsline/1993/feb/m9320068.html File Name: m9320068.html, Size: 9KB, Last Modified: Sunday, February 28, 1993 at 8:12:04 PM
2.	AEGiS-PRn: Targeted Genetics to Present at the 7th Annual Meeting of the American Society of Gene Therapy (88%) Abstract: -- Presentations Demonstrate Broad Potential of Company s AAV Technology SEATTLE, May 26 /PRNewswire-FirstCall/ -- Targeted Genetics Corporation s (Nasdaq: TGEN) technology assets will be highlighted in 12 presentations during the 7th Annual Meeting of the American Society of Gene Therapy. The meeting will take place J ... http://www.aegis.org/news/pr/2004/pr040541.html File Name: pr040541.html, Size: 11KB, Last Modified: Wednesday, May 26, 2004 at 3:00:00 PM
3.	AEGiS-14IAC: Oral administration of recombinant adeno-associated virus elicits protective immunity against HIV-1. (70%) Abstract: <p><b>BACKGROUND:</b> To study the ability of an adeno-associated virus vector expressing the env gene from HIV-1 (AAV-HIV) to induce a protective mucosal immune response when administered orally was studied. </p> <p><b>METHODS:</b> A single dose of 1010 particle AAV-HIV vector was orally administered into BALB/c mi ... http://www.aegis.org/conferences/iac/2002/a10144.html File Name: a10144.html, Size: 7KB, Last Modified: Monday, July 08, 2002 at 6:29:23 AM
4.	AEGiS-13IAC: Adeno-associated Virus Vector-Based Vaccine Induces Long-term Humoral and Cell-Mediated Immunity against Human Immunodeficiency Virus. (70%) Abstract: <p><b>BACKGROUND:</b> Adeno-associated virus (AAV) vector has been widely used for gene therapy in a variety of preclinical studies. The virus has infected most of the population and never shown any pathogenic effects in humans. AAV vector which can integrate into the cellular DNA has been shown to confer long-term g ... http://www.aegis.org/conferences/iac/2000/tuora289.html File Name: tuora289.html, Size: 8KB, Last Modified: Sunday, July 09, 2000 at 8:12:04 PM
5.	Recombinant adeno-associated virus expressing human papillomavirus type 16 E7 peptide DNA fused with heat shock protein DNA as a potential vaccine for cervical cancer. (70%) Abstract: In this study, we explore a potential vaccine for human papillomavirus (HPV)-induced tumors, using heat shock protein as an adjuvant, a peptide vaccine for safety, and adeno-associated virus (AAV) as a gene delivery vector. The tumor vaccine was devised by constructing a chimeric gene which contained HPV type 16 E7 cy ... http://www.aegis.org/aidsline/2000/jun/a0061654.html File Name: a0061654.html, Size: 10KB, Last Modified: Wednesday, June 28, 2000 at 8:12:04 PM
6.	Involvement of protein-DNA interaction in adeno-associated virus Rep78-mediated inhibition of HIV-1. (70%) Abstract: OBJECTIVE: It has been well documented by several laboratories that adeno-associated virus (AAV) is able to inhibit HIV-1 replication and gene expression. This effect has been mapped to the AAV-encoded Rep78 protein. However, the mechanism by which Rep78 is able to inhibit HIV-1 is unclear. As Rep78 is a DNA binding t ... http://www.aegis.org/aidsline/1999/jul/a9971133.html File Name: a9971133.html, Size: 10KB, Last Modified: Wednesday, July 28, 1999 at 8:12:04 PM
7.	Transduction of primitive human marrow and cord blood-derived hematopoietic progenitor cells with adeno-associated virus vectors. (70%) Abstract: We evaluated the capacity of adeno-associated virus (AAV) vectors to transduce primitive human myeloid progenitor cells derived from marrow and cord blood in long-term cultures and long-term culture-initiating cell (LTC-IC) assays. Single-colony analyses showed that AAV vectors transduced CD34(+) and CD34(+)38(-) clon ... http://www.aegis.org/aidsline/1999/jun/a9960996.html File Name: a9960996.html, Size: 10KB, Last Modified: Monday, June 28, 1999 at 8:12:04 PM
8.	Efficient gene transfer into primary and immortalized human fetal glial cells using adeno-associated virus vectors: establishment of a glial cell line with a functional CD4 receptor. (70%) Abstract: Adeno associated virus (AAV) is a non-pathogenic dependent parvovirus with a broad host range, capable of high levels of transduction and stable integration into the host cell genome. We have investigated the potential for using AAV as a vector for gene transfer into glial cells of the human fetal nervous system. Reco ... http://www.aegis.org/aidsline/1998/mar/m9831218.html File Name: m9831218.html, Size: 9KB, Last Modified: Sunday, March 29, 1998 at 6:29:23 AM
9.	Recombinant adeno-associated virus (rAAV) vectors for somatic gene therapy: recent advances and potential clinical applications. (70%) Abstract: Adeno-associated virus (AAV) is a single-stranded DNA dependovirus of the family of Parvoviridae that has promising features as a vector for somatic gene therapy. Different recombinant (r) AAV vectors have been generated that seem to have some advantages compared with other vector systems, such as the transduction of ... http://www.aegis.org/aidsline/1998/feb/m9820485.html File Name: m9820485.html, Size: 10KB, Last Modified: Sunday, March 01, 1998 at 6:29:23 AM
10.	Adeno-associated viral vectors: background and technical aspects. (70%) Abstract: There are several obstacles that prevent the successful clinical application of gene therapy. ... http://www.aegis.org/pubs/medline/1998/jan/m9819768.html File Name: m9819768.html, Size: 4KB, Last Modified: Saturday, January 31, 1998 at 10:00:00 PM
11.	Adeno-associated virus type 2-mediated gene transfer: correlation of tyrosine phosphorylation of the cellular single-stranded D sequence- binding protein with transgene expression in human cells in vitro and murine tissues in vivo. (70%) Abstract: Although the adeno-associated virus type 2 (AAV)-based vector system has gained attention as a potentially useful alternative t ... http://www.aegis.org/pubs/medline/1998/jan/m9812297.html File Name: m9812297.html, Size: 8KB, Last Modified: Saturday, January 31, 1998 at 10:00:00 PM
12.	Gene transfer into vascular cells using adeno-associated virus (AAV) vectors. (70%) Abstract: OBJECTIVES: Recombinant viral vectors based on the nonpathogenic parvovirus, adeno-associated virus (AAV), have a number of att ... http://www.aegis.org/pubs/medline/1998/jan/m9811336.html File Name: m9811336.html, Size: 5KB, Last Modified: Saturday, January 31, 1998 at 10:00:00 PM
13.	Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions. (70%) Abstract: The human parvovirus adeno-associated virus (AAV) infects a broad range of cell types, including human, nonhuman primate, canin ... http://www.aegis.org/pubs/medline/1998/jan/m9812313.html File Name: m9812313.html, Size: 6KB, Last Modified: Saturday, January 31, 1998 at 10:00:00 PM
14.	Transduction of the human immunodeficiency virus type 1 promoter into human chromosomal DNA by adeno-associated virus: effects on promoter activity. (70%) Abstract: Transcription of the human immunodeficiency virus type 1 (HIV-1) genome takes place after integration of the provirus into human chromosomal DNA. HIV transcription is known to be modulated by viral and cellular factors but the influence of flanking chromosomal sequences on proviral gene expression has not been well de ... http://www.aegis.org/aidsline/1997/oct/m97a0029.html File Name: m97a0029.html, Size: 9KB, Last Modified: Tuesday, October 28, 1997 at 8:12:04 PM
15.	Potent inhibition of human immunodeficiency virus type 1 in primary T cells and alveolar macrophages by a combination anti-Rev strategy delivered in an adeno-associated virus vector. (70%) Abstract: The rate of viral replication appears to play a pivotal role in human immunodeficiency virus type 1 (HIV-1) pathogenesis and disease progression as it outstrips the capacity of the immune system to respond. Important cellular sites for HIV-1 production include T lymphocytes and tissue macrophages. Antiviral strategies ... http://www.aegis.org/aidsline/1997/jul/m9772014.html File Name: m9772014.html, Size: 10KB, Last Modified: Monday, July 28, 1997 at 8:12:04 PM
16.	The adeno-associated virus Rep78 major regulatory/transformation suppressor protein binds cellular Sp1 in vitro and evidence of a biological effect. (70%) Abstract: Adeno-associated virus (AAV) Rep78 is a multifunctional protein that is required for AAV transcriptional activity, AAV DNA replication, and possibly for site-specific integration of AAV into human chromosome 19. Rep78 is also able to inhibit a variety of heterologous promoters, including those of c-H-ras, human papill ... http://www.aegis.org/aidsline/1997/mar/m9731042.html File Name: m9731042.html, Size: 10KB, Last Modified: Friday, March 28, 1997 at 8:12:04 PM
17.	Identification of mutant adeno-associated virus Rep proteins which are dominant-negative for DNA helicase activity. (70%) Abstract: Adeno-associated virus type 2 (AAV) Rep proteins have been postulated to play a role in unwinding the 145-bp inverted terminal repeats during AAV DNA replication. Previous studies showed that AAV Rep78 and Rep68 could unwind a DNA partial duplex of 26 bp. In this work it is demonstrated that nuclear extracts of human ... http://www.aegis.org/aidsline/1996/sep/m9690519.html File Name: m9690519.html, Size: 9KB, Last Modified: Saturday, September 28, 1996 at 8:12:04 PM
18.	High efficiency genetic modification of unstimulated primary CD8+ and CD34- cells using adeno-associated virus plasmid liposome complexes (Meeting abstract). (70%) Abstract: The widespread clinical use of gene therapy for the modification of primary T lymphocytes and hematopoietic stem cells has been limited by the relatively low transfection/infection efficiencies of these cells using current vector systems. We have observed that the combination of cationic liposomes with plasmids contai ... http://www.aegis.org/aidsline/1996/aug/m9680046.html File Name: m9680046.html, Size: 11KB, Last Modified: Wednesday, August 28, 1996 at 8:12:04 PM
19.	High efficiency gene modification of primary tumor, effector CD8+ T lymphocytes and CD34+ cells using adeno-associated virus plasmid DNA: liposome complexes for human cancer gene therapy (Meeting abstract). (70%) Abstract: Strategies including gene modification of primary tumor cells for vaccination, effector T lymphocytes and hematopoietic stem cells depend in large part upon the development of vector systems to efficiently introduce DNA into these cells. We have used cationic liposomes to facilitate plasmid DNA containing the inverted ... http://www.aegis.org/aidsline/1996/may/m9650033.html File Name: m9650033.html, Size: 10KB, Last Modified: Tuesday, May 28, 1996 at 8:12:04 PM
20.	Negative regulation of the adeno-associated virus (AAV) P5 promoter involves both the P5 rep binding site and the consensus ATP-binding motif of the AAV Rep68 protein. (70%) Abstract: Transcript levels from the P5 promoter of adeno-associated virus type 2 (AAV) are negatively regulated by the AAV Rep78 and Rep68 proteins in the absence of helper virus. We have identified a Rep-responsive negative cis element of the P5 promoter between the P5 TATA box and transcription start site by using 5 and 3 ... http://www.aegis.org/aidsline/1996/feb/m9620404.html File Name: m9620404.html, Size: 11KB, Last Modified: Wednesday, February 28, 1996 at 8:12:04 PM
21.	Adeno-Associated Virus mediated delivery of anti-HIV-1 genes by transduction or transfection: integration and efficiency studies. (70%) Abstract: The ability of wild type Adeno-Associated Virus (AAV) to integrate site-specifically into chromosome 19 and its wide tissue tropism, make this agent a unique candidate for use in gene therapy of HIV-1 infection. To further investigate the utility of this delivery system, we studied the transduction and integration cha ... http://www.aegis.org/aidsline/1995/dec/m95c2636.html File Name: m95c2636.html, Size: 10KB, Last Modified: Thursday, December 28, 1995 at 8:12:04 PM
22.	Efficient gene transfer to primary human CD4+ T lymphocytes, monocyte-macrophages, and CD34+ hematopoietic stem cells mediated by adeno-associated virus-based vectors: prospects for the gene therapy of AIDS. (70%) Abstract: One promising approach to the potential treatment of AIDS involves the genetic modification of HIV-susceptible target cells rendering them resistant to subsequent infection. Either mature, differentiated targets of HIV-infection (CD4+ T lymphocytes, monocyte-macrophages) or their progenitors (hematopoietic stem cells) ... http://www.aegis.org/aidsline/1995/dec/m95c2635.html File Name: m95c2635.html, Size: 10KB, Last Modified: Thursday, December 28, 1995 at 8:12:04 PM
23.	AEGiS-PRn: Targeted Genetics Names Bruce H. Devens Director of Immunology (70%) Abstract: SEATTLE, Dec. 7 /PRNewswire/ -- Targeted Genetics Corporation (Nasdaq: TGEN) has named Bruce H. Devens, Ph.D. to the position of director of immunology. He will have responsibility for directing Targeted Genetics immunology department, and will play a critical role in directing the company s cytotoxic T lymphocyte (CTL ... http://www.aegis.org/news/pr/1995/pr951215.html File Name: pr951215.html, Size: 9KB, Last Modified: Thursday, December 07, 1995 at 3:00:00 PM
24.	Mutational analysis of adeno-associated virus Rep protein-mediated inhibition of heterologous and homologous promoters. (70%) Abstract: The four Rep proteins encoded by adeno-associated virus type 2 (AAV-2) inhibit transcription of their own promoters and of several heterologous promoters. To gain insight into the molecular mechanism of Rep-mediated transcription repression, we studied the effects of the four Rep proteins on the accumulation of mRNA t ... http://www.aegis.org/aidsline/1995/nov/m95b0376.html File Name: m95b0376.html, Size: 11KB, Last Modified: Tuesday, November 28, 1995 at 8:12:04 PM
25.	Human herpesvirus 6A ts suppresses both transformation by H-ras and transcription by the H-ras and human immunodeficiency virus type 1 promoters. (70%) Abstract: Human herpesvirus 6 strain U1102 (HHV-6A) was shown to contain a 1,473-bp functional transformation suppressor gene (ts). ts exhibited 24% identity and 51% similarity to adeno-associated virus type 2 Rep68/78. Like adeno-associated virus type 2 Rep68/78, HHV-6A ts suppressed H-ras transformation of NIH 3T3 cells. Supp ... http://www.aegis.org/aidsline/1995/oct/m95a0386.html File Name: m95a0386.html, Size: 10KB, Last Modified: Saturday, October 28, 1995 at 8:12:04 PM
26.	The trans-inhibitory Rep78 protein of adeno-associated virus binds to TAR region DNA of the human immunodeficiency virus type 1 long terminal repeat. (70%) Abstract: The large rep gene products, Rep78 and Rep68, of adeno-associated virus (AAV) are pleiotropic effector proteins which are required for AAV DNA replication and the trans-regulation of AAV gene expression. Apart from these essential functions prerequisite for the life cycle of AAV, these rep products are able to inhibit ... http://www.aegis.org/aidsline/1995/oct/m95a0425.html File Name: m95a0425.html, Size: 10KB, Last Modified: Saturday, October 28, 1995 at 8:12:04 PM
27.	An improved system for packaging recombinant adeno-associated virus vectors capable of in vivo transduction. (70%) Abstract: Adeno-associated virus (AAV) vectors are potentially useful for gene therapy of a number of human diseases. However, the use of these vectors has been limited by the lack of stable vector-packaging cell lines. The difficulties in developing packaging cell lines relate to low levels of rep gene expression from the AAV- ... http://www.aegis.org/aidsline/1995/jul/m9570450.html File Name: m9570450.html, Size: 10KB, Last Modified: Friday, July 28, 1995 at 8:12:04 PM
28.	Human herpesvirus 6 (HHV-6) is a helper virus for adeno-associated virus type 2 (AAV-2) and the AAV-2 rep gene homologue in HHV-6 can mediate AAV-2 DNA replication and regulate gene expression. (70%) Abstract: We have previously described the apparent acquisition by human herpesvirus 6 (HHV-6) of the multifunctional rep gene of the helper-dependent human parvovirus adeno-associated virus type 2 (AAV-2). We report here that HHV-6 is a full helper virus for AAV-2 replication, suggesting a mechanism for transfer of the rep gen ... http://www.aegis.org/aidsline/1994/dec/m94c0210.html File Name: m94c0210.html, Size: 10KB, Last Modified: Wednesday, December 28, 1994 at 8:12:04 PM
29.	Efficient and sustained gene expression in primary T lymphocytes and primary and cultured tumor cells mediated by adeno-associated virus plasmid DNA complexed to cationic liposomes. (70%) Abstract: We have used cationic liposomes to facilitate adeno-associated virus (AAV) plasmid transfections of primary and cultured cell types. AAV plasmid DNA complexed with liposomes showed levels of expression several fold higher than those of complexes with standard plasmids. In addition, long-term expression (> 30 days) of ... http://www.aegis.org/aidsline/1994/jun/m9460211.html File Name: m9460211.html, Size: 11KB, Last Modified: Tuesday, June 28, 1994 at 8:12:04 PM
30.	Adeno-associated virus type 2 rep gene-mediated inhibition of basal gene expression of human immunodeficiency virus type 1 involves its negative regulatory functions. (70%) Abstract: Adeno-associated virus type 2 (AAV-2), a human parvovirus which is apathogenic in adults, inhibits replication and gene expression of human immunodeficiency virus type 1 (HIV-1) in human cells. The rep gene of AAV-2, which was shown earlier to be sufficient for this negative interference, also down-regulated the expre ... http://www.aegis.org/aidsline/1994/apr/m9440230.html File Name: m9440230.html, Size: 10KB, Last Modified: Thursday, April 28, 1994 at 8:12:04 PM
	1 2 3 4 Next
	AEGiS Search Engine. Status: The Index is up to date.