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1. (ATN) Pneumocystis Prophylaxis Overview (100%)
Abstract: Introduction In spite of recent improvements in treatment, pneumocystis pneumonia remains the most frequent cause of death in people with HIV infection. In addition, all currently available treatments have potentially serious toxicities associated with them. Therefore, the best approach to dealing with pneumocystis is ...
http://www.aegis.org/pubs/atn/1990/atn11401.html
File Name: atn11401.html, Size: 40KB, Last Modified: Monday, January 12, 2009 at 9:56:48 PM

2. Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome: pathophysiology, therapy, and prevention. (100%)
Abstract: The continuing growth of the acquired immunodeficiency syndrome (AIDS) epidemic has caused a parallel increase in patients with Pneumocystis carinii pneumonia (PCP). PCP has a wide spectrum of severity, from mild disease to severe parenchymal lung damage. Outcome is determined by severity of lung injury, the underlyin ...
http://www.aegis.org/aidsline/1989/oct/m89a0176.html
File Name: m89a0176.html, Size: 9KB, Last Modified: Wednesday, January 07, 2009 at 5:29:45 AM

3. Aerosolized pentamidine in HIV. Promising new treatment for Pneumocystis carinii pneumonia. (100%)
Abstract: Pneumocystis carinii pneumonia is the most common life-threatening disease diagnosed in patients infected with the human immunodeficiency virus (HIV). Patients treated for their initial episode are at risk for recurrence of the disease. HIV-positive patients with low T4 lymphocyte counts are also at risk. Conventional ...
http://www.aegis.org/aidsline/1989/nov/m89b0242.html
File Name: m89b0242.html, Size: 9KB, Last Modified: Wednesday, January 07, 2009 at 5:28:46 AM

4. Aerosolized pentamidine as second line therapy in patients with AIDS and Pneumocystis carinii pneumonia. (100%)
Abstract: The use of aerosolized pentamidine was investigated in ten patients with the acquired immunodeficiency syndrome (AIDS) and Pneumocystis carinii pneumonia (PCP) who had previous or concurrent severe adverse reactions or contraindications to trimethoprim-sulfamethoxazole or parenteral pentamidine. A dose of 600 mg penta ...
http://www.aegis.org/aidsline/1989/jul/m8970269.html
File Name: m8970269.html, Size: 9KB, Last Modified: Wednesday, January 07, 2009 at 5:25:47 AM

5. "Aerosolized Pentamidine Available Free in New Study" (100%)
Abstract: AEGIS, AIDS Daily Summary, HIV, AIDS, HIV infection, opportunistic infections. var gaJsHost = (https: = document.location.protocol) ? "https:ssl. : "http:www. document.write(unescape(3Cscript src= + gaJsHost + "google-analytics.com/ga.js' type=text/javascript'3E%3C/script%3E"ion" CONTENT=A new progra ...
http://www.aegis.org/news/ads/1988/ad881178.html
File Name: ad881178.html, Size: 13KB, Last Modified: Sunday, January 04, 2009 at 6:30:32 PM

6. "Blue Cross to Cover Aerosolized Pentamidine" (100%)
Abstract: AEGIS, AIDS Daily Summary, HIV, AIDS, HIV infection, opportunistic infections. var gaJsHost = (https: = document.location.protocol) ? "https:ssl. : "http:www. document.write(unescape(3Cscript src= + gaJsHost + "google-analytics.com/ga.js' type=text/javascript'3E%3C/script%3E"ion" CONTENT=Bowing to pr ...
http://www.aegis.org/news/ads/1988/ad880906.html
File Name: ad880906.html, Size: 14KB, Last Modified: Sunday, January 04, 2009 at 6:30:12 PM

7. AEGiS-FDA: Pentamidine (100%)
Abstract: The Food and Drug Administration today granted permission for the expanded distribution of an experimental, aerosolized version of the drug pentamidine to help prevent Pneumocystis carinii pneumonia, a potentially life-threatening infection that often afflicts AIDS patients. Under the conditions of the FDA-approved pro ...
http://www.aegis.org/news/fda/1989/fd890201.html
File Name: fd890201.html, Size: 10KB, Last Modified: Tuesday, March 06, 2007 at 5:40:11 PM

8. AEGiS-FDA: Second Aerosolized Pentamidine Approval (100%)
Abstract: HHS Secretary Louis W. Sullivan, M.D., today announced Food and Drug Administration approval of aerosolized pentamidine -- a drug inhaled into the lungs to help prevent a form of pneumonia that frequently threatens the lives of AIDS patients. Although many patients have already been receiving aerosolized pentamidine tr ...
http://www.aegis.org/news/fda/1989/fd890601.html
File Name: fd890601.html, Size: 11KB, Last Modified: Tuesday, March 06, 2007 at 5:40:11 PM

9. Simple Facts Sheets: preventing PCP (100%)
Abstract: a. Simple Facts Sheet. from the. AIDS Treatment Data Network. Preventing PCP. PCP stands for pneumocystis carinii pneumonia. This serious infection mainly affects the lungs, but it can also affect other organs, including the skin. Without preventive medication, over 80% of people with HIV will likely g ...
http://www.aegis.org/factshts/network/simple/pcp.html
File Name: pcp.html, Size: 6KB, Last Modified: Sunday, August 20, 2006 at 9:21:22 PM

10. Atovaquone suspension compared with aerosolized pentamidine for prevention of Pneumocystis carinii pneumonia in human immunodeficiency virus-infected subjects intolerant of trimethoprim or sulfonamides. (100%)
Abstract: Atovaquone suspensions (750 mg and 1500 mg once a day) were compared with aerosolized pentamidine (300 mg once a month) for the prevention of Pneumocystis carinii pneumonia (PCP) in subjects with human immunodeficiency virus (HIV) infection who were intolerant to trimethoprim or sulfonamides (or both). Median time usi ...
http://www.aegis.org/aidsline/1999/nov/a99b0710.html
File Name: a99b0710.html, Size: 10KB, Last Modified: Sunday, November 28, 1999 at 8:12:04 PM

11. Atovaquone Suspension Compared With Aerosolized Pentamidine for Prevention of Pneumocystis Carinii Pneumonia in Human Immunodeficiency Virus-Infected Subjects Intolerant of Trimethoprim or Sulfonamides (100%)
Abstract: Researchers from Toronto Hospital, Glaxo Wellcome , and elsewhere studied the efficacy of atovaquone suspensions versus aerosolized pentamidine for the prevention of Pneumocystis carinii pneumonia (PCP) in HIV-infected individuals who are intolerant to trimethoprim, sulfonamides, or both drugs. There were no significa ...
http://www.aegis.org/news/ads/1999/ad991305.html
File Name: ad991305.html, Size: 10KB, Last Modified: Tuesday, August 10, 1999 at 3:00:00 PM

12. (NIAID) TMP/SMX Better than Aerosolized Pentamidine for Preventing Recurrent PCP (100%)
Abstract: NIAID) TMP/SMX Better than Aerosolized Pentamidine for Preventing Recurrent PCP. National Institute of Allergy and Infectious Diseases, National Institutes of Health - December 23, 1992The oral drug trimethoprim-sulfamethoxazole (TMP/SMX) is better than aerosolized pentamidine for preventing a second episode ...
http://www.aegis.org/news/niaid/1992/na921201.html
File Name: na921201.html, Size: 8KB, Last Modified: Monday, September 21, 1998 at 12:59:19 PM

13. Opportunistic Infections & Other Complications: Pneumocystis Carinii Pneumonia (PCP) (100%)
Abstract: Opportunistic Infections & Other Complications: Pneumocystis Carinii Pneumonia (PCP). Seattle Treatment Education Project (STEP) Perspective, Vol. 5, No. 2 - July 1993 * 127 Broadway E. Ste 200 Seattle, WA 98102 Laury McKean, RNAlthough the incidence of Pneumocystis carinii pneumonia is declining due t ...
http://www.aegis.org/pubs/step/1993/step5208.html
File Name: step5208.html, Size: 6KB, Last Modified: Monday, September 21, 1998 at 12:53:11 PM

14. TMP/SMX Better than Aerosolized Pentamidine for Preventing Recurrent PCP (100%)
Abstract: TMP/SMX Better than Aerosolized Pentamidine for Preventing Recurrent PCP. News from NIAID - December 23, 1992 National Institute of Allergy and Infectious Diseases, National Institutes of HealthThe oral drug trimethoprim-sulfamethoxazole (TMP/SMX) is better than aerosolized pentamidine for preventing a second episode ...
http://www.aegis.org/pubs/cdc_fact_sheets/1993/cdc93092.html
File Name: cdc93092.html, Size: 8KB, Last Modified: Monday, September 21, 1998 at 12:52:53 PM

15. AEGiS-12IAC: Atovaquone suspension (ATQ) for prophylaxis of Pneumocystis carinii pneumonia (PCP): effects of baseline prophylaxis on safety and efficacy. (100%)
Abstract: <p><b>BACKGROUND:</b> The impact of prior drug experience on the outcome of clinical trials with antiretroviral drugs is well known. The role of prior experience with drugs for PCP prophylaxis is less well appreciated. We report results from two studies of ATQ for PCP prophylaxis in which the effects of baseline use ...
http://www.aegis.org/conferences/iac/1998/22178.html
File Name: 22178.html, Size: 8KB, Last Modified: Sunday, June 28, 1998 at 8:12:04 PM

16. Bacterial infections in adult patients hospitalized with AIDS: case-control study of prophylactic efficacy of trimethoprim-sulfamethoxazole versus aerosolized pentamidine. (100%)
Abstract: To determine the association between trimethoprim-sulfamethoxazole (TMP-SMX) prophylaxis for Pneumocystis carinii pneumonia and risk of bacterial infections in persons with AIDS, we abstracted hospital records from 6496 adult admissions to 42 hospitals in western Washington state. Of these admissions, 570 involved 637 ...
http://www.aegis.org/aidsline/1998/jan/m9810957.html
File Name: m9810957.html, Size: 9KB, Last Modified: Thursday, January 29, 1998 at 6:29:23 AM

17. Meta-analysis of prophylactic treatments against Pneumocystis carinii pneumonia and toxoplasma encephalitis in HIV-infected patients. (100%)
Abstract: In a meta-analysis, we examined the efficacy of aerosolized pentamidine, trimethoprim-sulfamethoxazole, and dapsone or dapsone/pyrimethamine for the prevention of Pneumocystis carinii pneumonia and toxoplasma encephalitis in patients with HIV infection. Of 22 trials, 13 compared trimethoprim-sulfamethoxazole with aero ...
http://www.aegis.org/aidsline/1997/nov/m97b0971.html
File Name: m97b0971.html, Size: 9KB, Last Modified: Friday, November 28, 1997 at 8:12:04 PM

18. Comparison of trimethoprim-sulfamethoxazole, dapsone, and pentamidine in the prophylaxis of Pneumocystis carinii pneumonia. (100%)
Abstract: STUDY OBJECTIVE: To compare the incidence of Pneumocystis carinii pneumonia (PCP) in patients infected with the human immunodeficiency virus (HIV) receiving one of three prophylactic agents. DESIGN: Retrospective chart review. SETTING: A university-affiliated Department of Veterans Affairs medical center HIV clinic. ...
http://www.aegis.org/aidsline/1997/may/m9750105.html
File Name: m9750105.html, Size: 10KB, Last Modified: Wednesday, May 28, 1997 at 8:12:04 PM

19. Effect of long-term primary aerosolized pentamidine prophylaxis on breakthrough Pneumocystis carinii pneumonia. (100%)
Abstract: Aerosolized pentamide is a well-tolerated primary prophylaxis regimen for Pneumocystis carinii pneumonia (PCP) in human immunodeficiency virus (HIV)-infected patients. It is now commonly administered for prolonged periods. We therefore studied the effect of long-term inhalation on breakthrough PCP. We recorded clinica ...
http://www.aegis.org/aidsline/1997/feb/m9720965.html
File Name: m9720965.html, Size: 10KB, Last Modified: Friday, February 28, 1997 at 8:12:04 PM

20. Meta-analysis of prophylactic treatments against pneumocystis carinii pneumonia and toxoplasmic encephalitis in HIV-infected patients. (100%)
Abstract: Objective: In a systemtic overview we examined the efficacy of aerosolized pentamidine, trimethoprim-sulphamethoxazole and dapsone or dapsone/pyrimethamine for the prevention of Pneumocystis carinii pneumonia and toxoplasmic encephalitis in patients with HIV infection. Methods: We identified all randomized controlled ...
http://www.aegis.org/aidsline/1997/jan/m9714909.html
File Name: m9714909.html, Size: 11KB, Last Modified: Tuesday, January 28, 1997 at 8:12:04 PM

21. Strategies for prophylaxis against pneumocystis pneumonia in persons with AIDS who become sensitized to trimethoprim - sulfamethoxazole: a cost-effectiveness analysis. (100%)
Abstract: Objective: To determine the most cost - effective strategy of prophylaxis against pneumocystis pneumonia for persons with AIDS and a history of adverse events attributable to trimethoprim - sulfamethoxazole. Methods: Decision analysis is used to explore the option of rechallenge with trimethoprim - sulfamethoxazole ve ...
http://www.aegis.org/aidsline/1997/jan/m9715659.html
File Name: m9715659.html, Size: 10KB, Last Modified: Tuesday, January 28, 1997 at 8:12:04 PM

22. Risks and benefits of aerosolized pentamidine and cotrimoxazole in primary prophylaxis of Pneumocystis carinii pneumonia in HIV-1-infected patients: a two-year Italian multicentric randomized controlled trial. The Italian PCP Study Group. (100%)
Abstract: We randomized 220 HIV-1-infected subjects to receive aerosolized pentamidine (300 mg/4 weeks) or orally trimethoprim-sulfamethoxazole (320-1600 mg/day) for primary prophylaxis of Pneumocystis carinii pneumonia (PCP), and evaluated PCP and toxoplasmic encephalitis (TE) occurrence and survival. Patients developing toxic ...
http://www.aegis.org/aidsline/1996/nov/m96b1511.html
File Name: m96b1511.html, Size: 10KB, Last Modified: Thursday, November 28, 1996 at 8:12:04 PM

23. AEGiS-11IAC: Meta-analysis of prophylactic treatments against pneumocystis carinii pneumonia and toxoplasmic encephalitis in HIV-infected patients. (100%)
Abstract: In a systemtic overview we examined the efficacy of aerosolized pentamidine, trimethoprim-sulphamethoxazole and dapsone or dapsone/pyrimethamine for the prevention of Pneumocystis carinii pneumonia and toxoplasmic encephalitis in patients with HIV infection. <p><b>METHODS</b>: We identified all randomized controlled ...
http://www.aegis.org/conferences/iac/1996/tub2289.html
File Name: tub2289.html, Size: 7KB, Last Modified: Sunday, July 07, 1996 at 8:12:04 PM

24. AEGiS-11IAC: Strategies for prophylaxis against pneumocystis pneumonia in persons with AIDS who become sensitized to trimethoprim - sulfamethoxazole: a cost-effectiveness analysis. (100%)
Abstract: To determine the most cost - effective strategy of prophylaxis against pneumocystis pneumonia for persons with AIDS and a history of adverse events attributable to trimethoprim - sulfamethoxazole. <p><b>METHODS</b>: Decision analysis is used to explore the option of rechallenge with trimethoprim - sulfamethoxazole ve ...
http://www.aegis.org/conferences/iac/1996/moc1581.html
File Name: moc1581.html, Size: 6KB, Last Modified: Sunday, July 07, 1996 at 8:12:04 PM

25. A meta-analysis of the relative efficacy and toxicity of Pneumocystis carinii prophylactic regimens. (100%)
Abstract: BACKGROUND: Finding the optimal strategy for Pneumocystis carinii prophylaxis in patients with human immunodeficiency virus infection can be problematic. Several prophylactic regimens are available, but their relative efficacy and tolerance are not well understood. METHODS: A meta-analysis overviewed 35 randomized tri ...
http://www.aegis.org/aidsline/1996/apr/m9640356.html
File Name: m9640356.html, Size: 11KB, Last Modified: Sunday, April 28, 1996 at 8:12:04 PM

26. Once-weekly administration of dapsone/pyrimethamine vs. aerosolized pentamidine as combined prophylaxis for Pneumocystis carinii pneumonia and toxoplasmic encephalitis in human immunodeficiency virus-infected patients. (100%)
Abstract: To evaluate combined prophylaxis for Pneumocystis carinii pneumonia (PCP) and toxoplasmic encephalitis, 533 patients with symptomatic human immunodeficiency virus infection and/or CD4 lymphocyte counts of ...
http://www.aegis.org/aidsline/1995/sep/m9590973.html
File Name: m9590973.html, Size: 11KB, Last Modified: Thursday, September 28, 1995 at 8:12:04 PM

27. Pentamidine aerosol versus trimethoprim-sulfamethoxazole for Pneumocystis carinii in acquired immune deficiency syndrome. (100%)
Abstract: Pneumocystis carinii pneumonia remains one of the most common opportunistic infections in patients with acquired immune deficiency syndrome (AIDS). Treatment with either intravenous pentamidine or trimethoprim-sulfamethoxazole (TMP-SMX) is frequently complicated by serious adverse reactions. This study was a prospecti ...
http://www.aegis.org/aidsline/1995/jul/m9570917.html
File Name: m9570917.html, Size: 11KB, Last Modified: Friday, July 28, 1995 at 8:12:04 PM

28. PCP Therapy: Aerosolized Pentamidine vs. TMP-SMX (100%)
Abstract: As part of a randomized study of treatments for Pneumocystis carinii pneumonia (PCP), researchers assigned 367 patients to 21 days of treatment with either aerosolized pentamidine or trimethoprim-sulfamethoxazole (TMP-SMX). Each group also received placebos imitating the opposite treatment. After 35 days, mortality in ...
http://www.aegis.org/news/ads/1995/ad951038.html
File Name: ad951038.html, Size: 9KB, Last Modified: Wednesday, June 07, 1995 at 3:00:00 PM

29. A Randomized Trial of Three Antipneumocystis Agents in Patients with Advanced Human Immunodeficiency Virus Infection (100%)
Abstract: Bozzette et al. evaluated the efficacy of three treatments for the prevention of a first episode of Pneumocystis carinii pneumonia (PCP) in HIV-infected patients. A combination of zidovudine and either trimethroprim-sulfamethoxazole, dapsone, or aerosolized pentamidine was given to 843 patients with HIV and CD4 counts ...
http://www.aegis.org/news/ads/1995/ad950559.html
File Name: ad950559.html, Size: 10KB, Last Modified: Monday, March 27, 1995 at 3:00:00 PM

30. Aerosolized pentamidine as primary prophylaxis for Pneumocystis carinii pneumonia: efficacy, mortality and morbidity [see comments] (100%)
Abstract: OBJECTIVE: Primary prophylaxis against Pneumocystis carinii pneumonia (PCP) for patients with HIV infection has been recommended by the Centers for Disease Control and Prevention. We evaluated alternatives to routine primary PCP prophylaxis with aerosolized pentamidine. METHODS: A total of 121 HIV-infected patients wi ...
http://www.aegis.org/aidsline/1995/feb/m9521003.html
File Name: m9521003.html, Size: 10KB, Last Modified: Tuesday, February 28, 1995 at 8:12:04 PM

 
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