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Abstract: The disorder, benign transient hyperphosphatasia, has been defined previously as a condition occurring in a normal child with spontaneous, transient elevation of alkaline phosphatase. We report three cases of hyperphosphatasia in patients with congenital HIV infection and underlying liver disease which appear to satis ...
http://www.aegis.org/aidsline/1989/jul/m8970249.html
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Abstract: Simple and sensitive methods to directly detect the human immunodeficiency virus (HIV) are needed for routine use in the clinical laboratory. In this study, we compared DNA probes prepared by: (1) nick translation with biotinylated dATP; (2) direct covalent biotinylation with photobiotin; (3) direct covalent reaction ...
http://www.aegis.org/aidsline/1988/oct/m88a0626.html
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Abstract: To assess the spectrum of hepatic abnormalities in acquired immune deficiency syndrome (AIDS), we reviewed clinical, biochemical, and pathological material in 32 patients with AIDS. Eight-four percent of AIDS cases had a history of intravenous drug abuse. Ninety percent of AIDS patients has some liver biochemical abno ...
http://www.aegis.org/aidsline/1987/jun/m8760296.html
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Abstract: AEGIS, AIDS Daily Summary, HIV, AIDS, HIV infection, opportunistic infections. var gaJsHost = (https: = document.location.protocol) ? "https:ssl. : "http:www. document.write(unescape(3Cscript src= + gaJsHost + "google-analytics.com/ga.js' type=text/javascript'3E%3C/script%3E"ion" CONTENT=A lymphocyte ...
http://www.aegis.org/news/ads/1994/ad941941.html
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Abstract: Vitamin D deficiency should be considered and ruled out in pateints presenting with a low phosphate and raised alkaline phosphatase. ...
http://www.aegis.org/conferences/bhiva/2008/p83.html
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Abstract: BACKGROUND: Disseminated infection with Histoplasma capsulatum and Mycobacterium avium complex (MAC) in patients with AIDS are frequently difficult to distinguish clinically. METHODS: We retrospectively compared demographic information, other opportunistic infections, medications, symptoms, physical examination findin ...
http://www.aegis.org/aidsline/2000/oct/a00a1055.html
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Abstract: AEGiS, 2nd LIPO, 2nd International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, Lipodystrophy, Adverse Drug Reactions, HIV, AIDS. 2nd International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV 13-15 September 2000, Toronto, CanadaSERUM AND URINE MARKERS OF BONE MINERAL METABOLISM ...
http://www.aegis.org/conferences/lipo/2000/o29.html
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Abstract: Zidovudine and stavudine had different effects on metabolism in mice, indicating these agents affect distinct metabolic pathways. Moreover, ascorbate and tocopherol reversed various effects of stavudine, indicating some metabolic changes associated with NRTIs may be due to increased oxidative stress. ...
http://www.aegis.org/conferences/lipo/2000/o8.html
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Abstract: HCMV infection can evoke the broad spectrum of symptoms, which may be caused by the responsible infection of many cell types. It is important to identify the cell types to be infected and replicated with HCMV infection for characterizing the property of HCMV infection and symptoms. Bone marrow stroma consists of heter ...
http://www.aegis.org/aidsline/2000/jul/a0070715.html
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Abstract: A 73-year-old man had fever, lymphadenopathy, granulocytopenia, thrombocytopenia, ascites, pleural effusion, liver injury, and an allergic-like skin rash. Autoantibodies, such as anti-nuclear antibody, were shown, and there were lactate dehydrogenase and alkaline phosphatase anomalies and platelet-associated IgG. His ...
http://www.aegis.org/aidsline/2000/mar/a0030870.html
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Abstract: All proteins which accumulate in the vacuolar space surrounding the obligate intracellular protozoan parasite Toxoplasma gondii are derived from parasite dense granules. To determine the signals for protein delivery to these secretory granules, and for subsequent secretion into the vacuolar space, T. gondii was stably ...
http://www.aegis.org/aidsline/1998/aug/m9880130.html
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Abstract: We are using viral oncogene probes to study the pathways by which osteoblast-specific gene expression is induced in ascorbic ac ...
http://www.aegis.org/pubs/medline/1998/jan/m9814164.html
File Name: m9814164.html, Size: 7KB, Last Modified: Saturday, January 31, 1998 at 10:00:00 PM
Abstract: Bisphosphonates (BPs) are inhibitors of bone resorption and soft tissue calcification. ...
http://www.aegis.org/pubs/medline/1998/jan/m9814172.html
File Name: m9814172.html, Size: 7KB, Last Modified: Saturday, January 31, 1998 at 10:00:00 PM
Abstract: OBJECTIVE: The introduction of recombinant genes into endothelial cells provides a method to study specific gene products and t ...
http://www.aegis.org/pubs/medline/1998/jan/m9811335.html
File Name: m9811335.html, Size: 7KB, Last Modified: Saturday, January 31, 1998 at 10:00:00 PM
Abstract: A unique alkaline phosphatase isoform found in the serum of HIV-1 infected patients is thought to originate from CD4 lymphocytes. Destruction of activated CD4 lymphocytes after HIV-1 infection is probably responsible for the appearance of this isoform in circulation. This band-10 alkaline phosphatase isoform is thus u ...
http://www.aegis.org/aidsline/1997/may/m9751078.html
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Abstract: OBJECTIVE: The aim of this study was to examine the interaction between HIV and hepatitis C virus (HCV) in hemophiliacs coinfected with the viruses and to investigate the possible relationship between immunosuppression and liver failure. METHODS: To identify risk factors for impending liver failure in hemophiliacs coi ...
http://www.aegis.org/aidsline/1997/mar/m9730462.html
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Abstract: The human immunodeficiency virus type 1 (HIV-1) genes vpu, env, and nef have all been implicated in modulating the levels of cell surface CD4 on infected cells. To quantitatively assess the relative contribution of each gene product to the regulation of CD4 during HIV infection of Jurkat T cells and peripheral blood m ...
http://www.aegis.org/aidsline/1996/nov/m96b1471.html
File Name: m96b1471.html, Size: 11KB, Last Modified: Thursday, November 28, 1996 at 8:12:04 PM
Abstract: For autogenous and allogeneic bone grafts, heat treatment has been thought to kill malignant cells and viruses such as human immunodeficiency virus. It is unclear whether heat treatment could preserve bone-inductive activity. Cortical bones from 6-week-old rat femurs were heated in a water bath at a temperature of 50 ...
http://www.aegis.org/aidsline/1995/nov/m95b0455.html
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Abstract: Binding and signaling proteins based on Escherichia coli alkaline phosphatase (AP; EC 3.1.3.1) were designed for the detection of antibodies. Hybrid proteins were constructed by using wild-type AP and point mutants of AP [Asp-101 --> Ser (D101S) and Asp-153 > Gly (D153G)]. The binding function of the hybrid proteins i ...
http://www.aegis.org/aidsline/1995/oct/m95a0088.html
File Name: m95a0088.html, Size: 9KB, Last Modified: Saturday, October 28, 1995 at 8:12:04 PM
Abstract: We report here on the construction and use of a novel human immunodeficiency virus (HIV) type 1 reporter vector, HIV-AP, that encodes human placental alkaline phosphatase. Upon staining with chromogenic alkaline phosphatase substrates 24 to 36 h postinfection, cells infected with HIV-AP develop an intense purple color ...
http://www.aegis.org/aidsline/1995/sep/m9590726.html
File Name: m9590726.html, Size: 10KB, Last Modified: Thursday, September 28, 1995 at 8:12:04 PM
Abstract: We prospectively determined the value of liver biopsy for microbiological diagnosis of infection in patients infected with the human immunodeficiency virus (HIV) who had unexplained fever and whose serum levels of alkaline phosphatase or gamma-glutamyl transferase were at least 1.5 times the upper limit of normal. Fro ...
http://www.aegis.org/aidsline/1995/sep/m9590969.html
File Name: m9590969.html, Size: 10KB, Last Modified: Thursday, September 28, 1995 at 8:12:04 PM
Abstract: We report the utility of a possible lymphocyte fraction of alkaline phosphatase (ALP band-10) activity in serum to predict human immunodeficiency virus type 1 (HIV-1) infection in children born to HIV-1-seropositive mothers. The presence of ALP band 10 in serum consistently correlated with HIV-1 infection status as ju ...
http://www.aegis.org/aidsline/1994/dec/m94c0526.html
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Abstract: An epitope from the HIV-1 gp120 protein V3 loop has been inserted onto the surface of bacterial alkaline phosphatase at different positions in the vicinity of the enzyme active site, creating hybrid proteins that can bind to an anti-gp120 monoclonal antibody. One of the hybrid proteins, API1, has a 13 amino acid V3 lo ...
http://www.aegis.org/aidsline/1994/oct/m94a0030.html
File Name: m94a0030.html, Size: 9KB, Last Modified: Friday, October 28, 1994 at 8:12:04 PM
Abstract: <p><b>OBJECTIVE</b>: 1. To evaluate the clinical characteristics of the tuberculous acute abdomen. 2. To determine the importance of the elevation of alkaline phosphatase as a diagnostic element. 3. To define the time of response to the specific therapeutics. 4. To study the patients evolution. <p><b>MATERIAL AND M ...
http://www.aegis.org/conferences/iac/1994/pb0677.html
File Name: pb0677.html, Size: 6KB, Last Modified: Thursday, August 04, 1994 at 8:12:04 PM
Abstract: Rifabutin (RIF) has recently been approved for prevention of disseminated Mycobacterium avium Complex (MAC) disease in patients with advanced HIV infection. A population pharmacokinetic analysis of data from a phase II study was preformed to test the hypothesis that the apparent clearance CL/F) and apparent volume (V/ ...
http://www.aegis.org/aidsline/1993/nov/m93b3606.html
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Abstract: The use of unlabeled antibody bridging technique with alkaline phosphatase monoclonal anti-alkaline phosphatase (APAAP) complexes makes it possible to solve the problem of short durability of immunofluorescent staining and the problem of nonspecific endogenous enzyme interference of blood cells with immunoperoxidase m ...
http://www.aegis.org/aidsline/1993/oct/m93a0760.html
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Abstract: A DNA amplification procedure using a heat stable DNA Polymerase and the polymerase chain reaction is described for the detection of HIV-1. A set of primers was designed to obtain a 500 b.p. amplification product from the gag region of a plasmid containing an inactivated version of HIV-1. Using this set of primers in ...
http://www.aegis.org/aidsline/1993/sep/m9391156.html
File Name: m9391156.html, Size: 9KB, Last Modified: Tuesday, September 28, 1993 at 8:12:04 PM
Abstract: Rifabutin (RIF) has recently been approved for prevention of disseminated Mycobacterium avium Complex ( MAC ) disease in patients with advanced HIV infection. A population pharmacokinetic analysis of data from a phase II study was preformed to test the hypothesis that the apparent clearance (CL/F) and apparent volume ( ...
http://www.aegis.org/conferences/iac/1993/pob312221.html
File Name: pob312221.html, Size: 5KB, Last Modified: Sunday, June 06, 1993 at 8:12:04 PM
Abstract: The hybridization characteristics of oligonucleotide-alkaline phosphatase conjugate probes were examined in bead-based sandwich hybridization reactions using single-stranded nucleic acid targets and oligonucleotide-polystyrene capture beads. Enzymatic activity was monitored using a chemiluminescent substrate and calib ...
http://www.aegis.org/aidsline/1993/may/m9350027.html
File Name: m9350027.html, Size: 10KB, Last Modified: Friday, May 28, 1993 at 8:12:04 PM
Abstract: By means of an electrofocusing technique, the serum specimens of pregnant women routinely revealed three bands of alkaline phosphatase (ALP) that were released by placental syncytiotrophoblast, germ cell (ovary), and fetal intestine at pl of 4.73, 4.65, and 4.55, respectively. When defining reference ranges for ostens ...
http://www.aegis.org/aidsline/1993/jan/m9310280.html
File Name: m9310280.html, Size: 9KB, Last Modified: Thursday, January 28, 1993 at 8:12:04 PM