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Abstract: BACKGROUND: COBAS AMPLICOR system has played a major role in routine molecular diagnostics in Thailand since 1997. Now COBAS AmpliPrep® machine has been introduced in October 2002 and used for automated specimen preparation followed by COBAS Amplicor for amplification and detection process. OBJECTIVE: We compared ...
http://www.aegis.org/conferences/iac/2004/b12625.html
File Name: b12625.html, Size: 6KB, Last Modified: Monday, May 11, 2009 at 10:19:10 PM
Abstract: A modified version of the AMPLICOR HIV-1 MONITOR version 1.5 can detect HIV RNA at previously undetectable levels. ...
http://www.aegis.org/pubs/aidswkly/2003/aw030911.html
File Name: aw030911.html, Size: 9KB, Last Modified: Monday, January 05, 2009 at 9:58:30 PM
Abstract: PLEASANTON, Calif.--(BUSINESS WIRE)--Jan. 30, 2001--Roche Molecular Systems announced today that its new automated, viral load in vitro diagnostic test for HIV-1 has been accepted for review by the U.S. Food and Drug Administration ( FDA ). This assay, called the COBAS AMPLICOR HIV-1 MONITOR(TM) Test, version 1.5, uses ...
http://www.aegis.org/news/bw/2001/bw010110.html
File Name: bw010110.html, Size: 10KB, Last Modified: Tuesday, March 06, 2007 at 5:33:29 PM
Abstract: BRANCHBURG, N.J.--(BW HealthWire)--March 3, 1999-- Roche today received marketing approval from the U.S. Food and Drug Administration ( FDA ) for its AMPLICOR HIV-1 MONITOR UltraSensitive Method. This test is now the most sensitive means to measure levels of HIV circulating in an infected person s blood ( viral load ). ...
http://www.aegis.org/news/bw/1999/bw990302.html
File Name: bw990302.html, Size: 11KB, Last Modified: Tuesday, March 06, 2007 at 5:33:09 PM
Abstract: In our study, a statistically significant difference was found between the results of viral load measurements obtained using the NucliSens EasyQ assay and those obtained by Amplicor HIV-1 Monitor assay Version 1.5, in subtype-C-infected patients. This difference may have significant bearing on patient care. ...
http://www.aegis.org/conferences/croi/2005/736.html
File Name: 736.html, Size: 7KB, Last Modified: Tuesday, February 22, 2005 at 8:12:04 PM
Abstract: Introduction HIV-1 viral load is an important tool for monitoring of HIV-1 infection. In order to widely used in poor resource countries, we have developed the methods that simple and inexpensive for quantification HIV-1 RNA level. Methods HIV-1 RNA from plasma samples were co-extracted with BMV RNA for internal contro ...
http://www.aegis.org/conferences/iac/2004/mopeb3143.html
File Name: mopeb3143.html, Size: 6KB, Last Modified: Monday, July 12, 2004 at 6:29:23 AM
Abstract: We conclude that acute exercise is safe in people with HIV-1 infection because it does not increase HIV-1 viral load. These data are relevant in the perspective of future exercise strategies for the management of HAART-associated hyperlipidemia and lipodystrophy. ...
http://www.aegis.org/conferences/eacs/2001/posters/133.html
File Name: 133.html, Size: 9KB, Last Modified: Monday, January 05, 2004 at 7:10:11 PM
Abstract: AEGIS, 8th EUROPEAN CONFERENCE ON CLINIC ASPECTS AND TREATMENT OF HIV - INFECTION. Abstract Form. REFERENCE NUMBER : 166. ECCATH ID : P217. 8th EUROPEAN CONFERENCE ON CLINIC ASPECTS AND TREATMENT OF HIV - INFECTION. Location of research or project (country). USA. Thematic Areas:. 4.1. Pre-clinical development. Title. ...
http://www.aegis.org/conferences/eacs/2001/posters/283.html
File Name: 283.html, Size: 8KB, Last Modified: Monday, December 29, 2003 at 10:30:25 PM
Abstract: BASEL, Switzerland , April 11 /PRNewswire/ -- Roche today announced that it has received clearance from the U.S. Food and Drug Administration ( FDA ) for the Cobas Amplicor HIV-1 Monitor Test (version 1.5) an enhanced version of Roche s polymerase chain reaction (PCR) assay used to measure the amount of HIV-1 RNA (vira ...
http://www.aegis.org/news/pr/2003/pr030426.html
File Name: pr030426.html, Size: 10KB, Last Modified: Friday, April 11, 2003 at 3:00:00 PM
Abstract: Human immunodeficiency virus type 1 (HIV-1) RNA levels in female genital tract and peripheral blood samples were compared using two commercial amplification technologies: the Roche AMPLICOR HIV-1 MONITOR test and either the Organon Teknika nucleic acid sequence-based amplification (NASBA-QT) assay or the NucliSens ass ...
http://www.aegis.org/aidsline/2000/nov/a00b0785.html
File Name: a00b0785.html, Size: 10KB, Last Modified: Tuesday, November 28, 2000 at 8:12:04 PM
Abstract: As clinical trials continue to examine therapies which drive the plasma viral load to undetectable levels, other reservoirs of HIV-1 are of potential importance in determination of efficacy. Peripheral blood mononuclear cells (PBMCs) are an important reservoir of HIV-1 proviral DNA and viral RNA. Amplicor HIV-1 Monitor ...
http://www.aegis.org/conferences/iac/2000/mopea2133.html
File Name: mopea2133.html, Size: 8KB, Last Modified: Sunday, July 09, 2000 at 8:12:04 PM
Abstract: <p><b>BACKGROUND:</b> In HIV-1 infection, viral load monitoring is a standard clinical management tool. Recommendations to start or to change antiretroviral therapy are based on changes in the patients viral load. At the moment there are three different commercially available quantitative tests to measure HIV-load in ...
http://www.aegis.org/conferences/iac/2000/mopea2129.html
File Name: mopea2129.html, Size: 7KB, Last Modified: Sunday, July 09, 2000 at 8:12:04 PM
Abstract: The COBAS AMPLICOR HIV-1 MONITOR Test, v1.5 is an automated RT-PCR-based test for measurement of HIV-1 viral load. The sensitivity, linear range, performance on Group M subtypes of HIV-1, and correlation to the manual AMPLICOR HIV-1 MONITOR Test, v1.5 were determined in a multi-center trial. Blinded test panels were p ...
http://www.aegis.org/aidsline/2000/jun/a0060347.html
File Name: a0060347.html, Size: 9KB, Last Modified: Wednesday, June 28, 2000 at 8:12:04 PM
Abstract: The TaqMan assay provides real-time amplification and detection of PCR products. We have developed a TaqMan assay for HIV that has a detection range of 50-7x10<sup>5</sup> copies/mL when co-amplified with an internal quantitation standard (QS). The performance of this assay was compared with the AMPLICOR HIV-1 MONITOR ...
http://www.aegis.org/conferences/croi/2000/771.html
File Name: 771.html, Size: 5KB, Last Modified: Sunday, January 30, 2000 at 8:12:04 PM
Abstract: <p><b>Objective:</b> To demonstrate that the automated COBAS AMPLICOR HIV-1 MONITOR Test, Version 1.5 exhibits performance characteristics comparable to the AMPLICOR HIV-1 MONITOR Test, Version 1.5. Background: The COBAS AMPLICOR HIV-1 MONITOR Test, Version 1.5 is the first HIV-1 viral load test that fully automates am ...
http://www.aegis.org/conferences/croi/2000/772.html
File Name: 772.html, Size: 6KB, Last Modified: Sunday, January 30, 2000 at 8:12:04 PM
Abstract: OBJECTIVE: To assess the clinical significance of HIV-1 RNA levels detectable using the Amplicor HIV-1 Monitor method but ...
http://www.aegis.org/aidsline/1999/dec/a99c0364.html
File Name: a99c0364.html, Size: 11KB, Last Modified: Tuesday, December 28, 1999 at 8:12:04 PM
Abstract: Accurate determination of plasma human immunodeficiency virus type 1 (HIV-1) RNA levels is critical for the effective management of HIV-1 disease. The AMPLICOR HIV-1 MONITOR Test, a reverse transcription-PCR-based test for quantification of HIV-1 RNA in plasma, was developed when little sequence information on HIV-1 i ...
http://www.aegis.org/aidsline/1999/oct/a99a0582.html
File Name: a99a0582.html, Size: 10KB, Last Modified: Thursday, October 28, 1999 at 8:12:04 PM
Abstract: We compared the QUANTIPLEX HIV-1 RNA 2.0 assay with the AMPLICOR HIV-1 MONITOR 1.0 assay for quantitation of human immunodeficiency virus type 1 (HIV-1) RNA in plasma in the Stadi trail, which evaluated a stavudine plus didanosine ...
http://www.aegis.org/aidsline/1999/feb/a9920523.html
File Name: a9920523.html, Size: 10KB, Last Modified: Sunday, February 28, 1999 at 8:12:04 PM
Abstract: OBJECTIVES: To compare the performance of the Roche Amplicor HIV-1 Monitor version 1.5 polymerase chain reaction (PCR) assay with that of the standard Roche Amplicor PCR assay for detection of HIV-1 DNA in samples from Tanzanian adults. METHODS: Blood samples from 106 HIV-1 seropositive and 23 HIV-1 seronegative pregn ...
http://www.aegis.org/aidsline/1998/dec/m98c2615.html
File Name: m98c2615.html, Size: 10KB, Last Modified: Tuesday, December 29, 1998 at 6:29:23 AM
Abstract: OBJECTIVES: To establish sensitive methods to monitor levels of HIV RNA in plasma, peripheral blood mononuclear cells (PBMC) and lymphoid tissues from HIV-infected subjects. DESIGN: Modified forms of the Amplicor HIV-1 Monitor test (Roche Diagnostic Systems) was used to examine specimens from plasma, PBMCs and lymphoi ...
http://www.aegis.org/aidsline/1998/dec/m98c2636.html
File Name: m98c2636.html, Size: 9KB, Last Modified: Tuesday, December 29, 1998 at 6:29:23 AM
Abstract: OBJECTIVES: To quantitate HIV-1 RNA in plasma from Ghanaian HIV seropositive patients and to assess any HIV-2 interference. METHODS: Plasma was obtained from patients in southern Ghana during 1996 and 1997. After screening for HIV-1 and HIV-2 antibodies with confirmation by PCR, 130 (including 18 known HIV-1 subtype A ...
http://www.aegis.org/aidsline/1998/dec/m98c0723.html
File Name: m98c0723.html, Size: 9KB, Last Modified: Tuesday, December 29, 1998 at 6:29:23 AM
Abstract: OBJECTIVE: To determine the linear range of the Amplicor HIV-1 Monitor Ultra Sensitive Specimen Preparation Protocol which increases the sensitivity of the FDA approved Amplicor HIV-1 Monitor assay 10-fold by decreasing the lower limit of detection to 40 copy/ml. METHODS: A clinical s ...
http://www.aegis.org/aidsline/1998/dec/m98c2623.html
File Name: m98c2623.html, Size: 10KB, Last Modified: Tuesday, December 29, 1998 at 6:29:23 AM
Abstract: OBJECTIVES: Determine the sensitivity, linear range, precision and performance on Group M subtypes of HIV-1 of the AMPLICOR HIV-1 MONITOR Test, version 1.5, and an automated version of the test, the COBAS AMPLICOR HIV-1 MONITOR Test. The HIV-1 MONITOR version 1.5 is an upgraded test with new PCR primers designed to yi ...
http://www.aegis.org/aidsline/1998/dec/m98c2639.html
File Name: m98c2639.html, Size: 10KB, Last Modified: Tuesday, December 29, 1998 at 6:29:23 AM
Abstract: BACKGROUNDS: Comparison between plasma HIV RNA viral load results obtained using the Roche Amplicor HIV-1 Monitor assay version 1.0, same assay plus additional primer pair Add-in Primers distributed by Roche and Amplicor HIV-1 Monitor assay version 1.5. METHODS: Plasma Viral load of 176 HIV-1 infected patients enrol ...
http://www.aegis.org/aidsline/1998/dec/m98c2468.html
File Name: m98c2468.html, Size: 10KB, Last Modified: Tuesday, December 29, 1998 at 6:29:23 AM
Abstract: The performance of three versions of the AMPLICOR HIV-1 MONITOR Test (Roche Diagnostics) was evaluated on 96 patient samples of known subtype from Cameroon and France . All patients were African, or believed to be infected by African contacts. ...
http://www.aegis.org/aidsline/1998/jun/m9860631.html
File Name: m9860631.html, Size: 9KB, Last Modified: Monday, June 29, 1998 at 6:29:23 AM
Abstract: <p><b>OBJECTIVES:</b> Three versions of the AMPLICOR HIV-1 Monitor Test (v1.0, v1.0+ and v1.5) and a prototype automated version of the v1.5 test (Cobas Amplicor HIV-1 Monitor), with different gag primers, were evaluated for their ability to detect and quantify HIV-1 RNA from different genetic subtypes. </p> <p><b>M ...
http://www.aegis.org/conferences/iac/1998/41145.html
File Name: 41145.html, Size: 7KB, Last Modified: Sunday, June 28, 1998 at 8:12:04 PM
Abstract: <p><b>OBJECTIVES:</b> To compare the performance of the Roche Amplicor HIV-1 Monitor version 1.5 polymerase chain reaction (PCR) assay with that of the standard Roche Amplicor PCR assay for detection of HIV-1 DNA in samples from Tanzanian adults. </p> <p><b>METHODS:</b> Blood samples from 106 HIV-1 seropositive and ...
http://www.aegis.org/conferences/iac/1998/41155.html
File Name: 41155.html, Size: 7KB, Last Modified: Sunday, June 28, 1998 at 8:12:04 PM
Abstract: <p><b>OBJECTIVES:</b> To establish sensitive methods to monitor levels of HIV RNA in plasma, peripheral blood mononuclear cells (PBMC) and lymphoid tissues from HIV-infected subjects. <p><b>DESIGN:</b> Modified forms of the Amplicor HIV-1 Monitor test (Roche Diagnostic Systems) was used to examine specimens from pl ...
http://www.aegis.org/conferences/iac/1998/41133.html
File Name: 41133.html, Size: 7KB, Last Modified: Sunday, June 28, 1998 at 8:12:04 PM
Abstract: <p><b>OBJECTIVES:</b> To quantitate HIV-1 RNA in plasma from Ghanaian HIV seropositive patients and to assess any HIV-2 interference. </p> <p><b>METHODS:</b> Plasma was obtained from patients in southern Ghana during 1996 and 1997. After screening for HIV-1 and HIV-2 antibodies with confirmation by PCR, 130 (includi ...
http://www.aegis.org/conferences/iac/1998/60773.html
File Name: 60773.html, Size: 7KB, Last Modified: Sunday, June 28, 1998 at 8:12:04 PM
Abstract: <p><b>OBJECTIVE:</b> To determine the linear range of the Amplicor HIV-1 Monitor Ultra Sensitive Specimen Preparation Protocol which increases the sensitivity of the FDA approved Amplicor HIV-1 Monitor assay 10-fold by decreasing the lower limit of detection to 40 copy/ml. </p> <p><b>METHODS:</b> A clinical sample s ...
http://www.aegis.org/conferences/iac/1998/41146.html
File Name: 41146.html, Size: 7KB, Last Modified: Sunday, June 28, 1998 at 8:12:04 PM